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Svopl SV2 related protein homolog (rat)-like [ Mus musculus (house mouse) ]

Gene ID: 320590, updated on 5-Mar-2024

Summary

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Official Symbol
Svoplprovided by MGI
Official Full Name
SV2 related protein homolog (rat)-likeprovided by MGI
Primary source
MGI:MGI:2444335
See related
Ensembl:ENSMUSG00000029830 AllianceGenome:MGI:2444335
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9430071P14Rik
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in genitourinary system and nose. Orthologous to human SVOPL (SVOP like). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in kidney adult (RPKM 1.9), genital fat pad adult (RPKM 0.7) and 10 other tissues See more
Orthologs
human all
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Genomic context

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Location:
6 B1; 6 17.34 cM
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (37960674..38023944, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (37983739..38047009, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr6:37820554-37820855 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:37821510-37821693 Neighboring gene general transcription factor IIB pseudogene Neighboring gene STARR-seq mESC enhancer starr_15610 Neighboring gene tripartite motif-containing 24 Neighboring gene STARR-positive B cell enhancer mm9_chr6:37846121-37846422 Neighboring gene STARR-seq mESC enhancer starr_15611 Neighboring gene STARR-seq mESC enhancer starr_15612 Neighboring gene vomeronasal 2, receptor 121 pseudogene Neighboring gene predicted gene, 33494 Neighboring gene ATPase, H+ transporting, lysosomal V0 subunit A4 Neighboring gene predicted gene, 57763 Neighboring gene transmembrane protein 213

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family. Jacobsson JA, et al. Genomics, 2007 Nov. PMID 17714910
  2. Novel genes differentially expressed in cortical regions during late neurogenesis. Mühlfriedel S, et al. Eur J Neurosci, 2007 Jul. PMID 17614941
  3. Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. Gerber SD, et al. PLoS One, 2012. PMID 22432025, Free PMC Article
  4. Expression of metanephric nephron-patterning genes in differentiating mesonephric tubules. Georgas KM, et al. Dev Dyn, 2011 Jun. PMID 21491542, Free PMC Article
  5. Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment. Georgas K, et al. Dev Biol, 2009 Aug 15. PMID 19501082

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
putative transporter SVOPL
Names
SVOP-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177200.4 → NP_796174.2  putative transporter SVOPL

    See identical proteins and their annotated locations for NP_796174.2

    Status: VALIDATED

    Source sequence(s)
    BB627230, BC058741
    Consensus CDS
    CCDS20009.2
    UniProtKB/Swiss-Prot
    Q6PDF3, Q8BM44
    Related
    ENSMUSP00000093743.5, ENSMUST00000096040.11
    Conserved Domains (2) summary
    cd06174
    Location:51 → 482
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00895
    Location:34 → 456
    2A0115; benzoate transport

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    37960674..38023944 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011241386.4 → XP_011239688.1  putative transporter SVOPL isoform X1

    Conserved Domains (1) summary
    cd17442
    Location:49 → 482
    MFS_SVOPL; Synaptic vesicle 2 (SV2)-related protein-like (SVOPL) of the Major Facilitator Superfamily

  2. XM_017321644.2 → XP_017177133.1  putative transporter SVOPL isoform X2

    Conserved Domains (1) summary
    cl28910
    Location:49 → 225
    MFS; Major Facilitator Superfamily
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6PDF3.1 GenPept UniProtKB/Swiss-Prot:Q6PDF3

Gene LinkOut

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