U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Islr2 immunoglobulin superfamily containing leucine-rich repeat 2 [ Mus musculus (house mouse) ]

Gene ID: 320563, updated on 21-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
Islr2provided by MGI
Official Full Name
immunoglobulin superfamily containing leucine-rich repeat 2provided by MGI
Primary source
MGI:MGI:2444277
See related
Ensembl:ENSMUSG00000051243 AllianceGenome:MGI:2444277
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Linx; Mbu-3; mKIAA1465; B930052A04Rik
Summary
Involved in positive regulation of axon extension. Located in cell surface. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and sensory organ. Orthologous to human ISLR2 (immunoglobulin superfamily containing leucine rich repeat 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in whole brain E14.5 (RPKM 62.5), CNS E14 (RPKM 61.4) and 5 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
9 B; 9 31.63 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (58103580..58113563, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (58196297..58204319, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene immunoglobulin superfamily containing leucine-rich repeat Neighboring gene predicted gene, 39344 Neighboring gene ribosomal protein L17 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E10552 Neighboring gene microRNA 6385 Neighboring gene promyelocytic leukemia Neighboring gene STARR-positive B cell enhancer ABC_E2891 Neighboring gene stomatin-like 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Characterization of tissue-specific mbu-3 gene expression in the mouse central nervous system. Lee CJ, et al. BMB Rep, 2008 Dec 31. PMID 19123979
  2. The LRR and Ig domain-containing membrane protein SST273 is expressed on motoneurons. Gejima R, et al. Gene Expr Patterns, 2006 Mar. PMID 16378755
  3. Essential Role of Linx/Islr2 in the Development of the Forebrain Anterior Commissure. Abudureyimu S, et al. Sci Rep, 2018 May 8. PMID 29739947, Free PMC Article
  4. Linx mediates interaxonal interactions and formation of the internal capsule. Mandai K, et al. Neuron, 2014 Jul 2. PMID 24930700, Free PMC Article
  5. LIG family receptor tyrosine kinase-associated proteins modulate growth factor signals during neural development. Mandai K, et al. Neuron, 2009 Sep 10. PMID 19755105, Free PMC Article

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. These data suggest a role for Linx in the regulation of complex forebrain connectivity, and future identification of its extracellular ligand(s) will help clarify this function.
    Title: Essential Role of Linx/Islr2 in the Development of the Forebrain Anterior Commissure.
  2. we identify a novel role for the LRR receptor Islr2 in ensuring proper axon navigation at the optic chiasm of both zebrafish and mouse.
    Title: The LRR receptor Islr2 is required for retinal axon routing at the vertebrate optic chiasm.
  3. Linx guides the extension of thalamocortical axons in the ventral forebrain.
    Title: Linx mediates interaxonal interactions and formation of the internal capsule.
  4. These findings show that LIGs such as Linx physically interact with Trk receptor tyrosine kinases and modulate their activities to control axonal extension, guidance and branching
    Title: LIG family receptor tyrosine kinase-associated proteins modulate growth factor signals during neural development.
  5. During the embryonic stages, mbu-3 was localized to the central nervous system in the brain and spinal cord. In the early post-natal stages, the gene was evenly expressed in the brain.
    Title: Characterization of tissue-specific mbu-3 gene expression in the mouse central nervous system.
Submit: New GeneRIF Correction

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within nervous system development IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of axon extension IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of axon extension IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cell surface IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cell surface IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
immunoglobulin superfamily containing leucine-rich repeat protein 2
Names
leucine-rich repeat domain and immunoglobulin domain containing axon extension protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001161535.1 → NP_001155007.1  immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (a).
    Source sequence(s)
    BC096531
    Consensus CDS
    CCDS52812.1
    UniProtKB/TrEMBL
    E9Q9N7
    Related
    ENSMUSP00000130879.2, ENSMUST00000163200.3
    Conserved Domains (5) summary
    smart00082
    Location:225 → 273
    LRRCT; Leucine rich repeat C-terminal domain
    sd00033
    Location:80 → 96
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:144 → 183
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:164 → 227
    LRR_8; Leucine rich repeat
    pfam13895
    Location:288 → 417
    Ig_2; Immunoglobulin domain

  2. NM_001161536.1 → NP_001155008.1  immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform b precursor

    See identical proteins and their annotated locations for NP_001155008.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream translational start codon, compared to variant 1. The encoded isoform (b) is shorter than isoform a. Variants 2-8 encode the same isoform.
    Source sequence(s)
    BC096531, CA325040, CA328406
    Consensus CDS
    CCDS23238.1
    UniProtKB/Swiss-Prot
    C8XPY9, Q5RKR3, Q6ZPQ3
    Related
    ENSMUSP00000130322.2, ENSMUST00000163897.8
    Conserved Domains (6) summary
    TIGR00864
    Location:154 → 228
    PCC; polycystin cation channel protein
    sd00033
    Location:36 → 52
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:99 → 159
    LRR_8; Leucine rich repeat
    pfam13927
    Location:232 → 360
    Ig_3; Immunoglobulin domain
    cd00096
    Location:256 → 263
    Ig; Ig strand B [structural motif]
    cl11960
    Location:351 → 373
    Ig; Immunoglobulin domain

  3. NM_001161537.1 → NP_001155009.1  immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform b precursor

    See identical proteins and their annotated locations for NP_001155009.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream translational start codon, compared to variant 1. The encoded isoform (b) is shorter than isoform a. Variants 2-8 encode the same isoform.
    Source sequence(s)
    BC096531, CB526596
    Consensus CDS
    CCDS23238.1
    UniProtKB/Swiss-Prot
    C8XPY9, Q5RKR3, Q6ZPQ3
    Conserved Domains (6) summary
    TIGR00864
    Location:154 → 228
    PCC; polycystin cation channel protein
    sd00033
    Location:36 → 52
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:99 → 159
    LRR_8; Leucine rich repeat
    pfam13927
    Location:232 → 360
    Ig_3; Immunoglobulin domain
    cd00096
    Location:256 → 263
    Ig; Ig strand B [structural motif]
    cl11960
    Location:351 → 373
    Ig; Immunoglobulin domain

  4. NM_001161538.1 → NP_001155010.1  immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform b precursor

    See identical proteins and their annotated locations for NP_001155010.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream translational start codon, compared to variant 1. The encoded isoform (b) is shorter than isoform a. Variants 2-8 encode the same isoform.
    Source sequence(s)
    BC096531, CA750352
    Consensus CDS
    CCDS23238.1
    UniProtKB/Swiss-Prot
    C8XPY9, Q5RKR3, Q6ZPQ3
    Related
    ENSMUSP00000127228.2, ENSMUST00000170421.8
    Conserved Domains (6) summary
    TIGR00864
    Location:154 → 228
    PCC; polycystin cation channel protein
    sd00033
    Location:36 → 52
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:99 → 159
    LRR_8; Leucine rich repeat
    pfam13927
    Location:232 → 360
    Ig_3; Immunoglobulin domain
    cd00096
    Location:256 → 263
    Ig; Ig strand B [structural motif]
    cl11960
    Location:351 → 373
    Ig; Immunoglobulin domain

  5. NM_001161539.1 → NP_001155011.1  immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform b precursor

    See identical proteins and their annotated locations for NP_001155011.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream translational start codon, compared to variant 1. The encoded isoform (b) is shorter than isoform a. Variants 2-8 encode the same isoform.
    Source sequence(s)
    BC096531, CD350184
    Consensus CDS
    CCDS23238.1
    UniProtKB/Swiss-Prot
    C8XPY9, Q5RKR3, Q6ZPQ3
    Conserved Domains (6) summary
    TIGR00864
    Location:154 → 228
    PCC; polycystin cation channel protein
    sd00033
    Location:36 → 52
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:99 → 159
    LRR_8; Leucine rich repeat
    pfam13927
    Location:232 → 360
    Ig_3; Immunoglobulin domain
    cd00096
    Location:256 → 263
    Ig; Ig strand B [structural motif]
    cl11960
    Location:351 → 373
    Ig; Immunoglobulin domain

  6. NM_001161540.1 → NP_001155012.1  immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform b precursor

    See identical proteins and their annotated locations for NP_001155012.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream translational start codon, compared to variant 1. The encoded isoform (b) is shorter than isoform a. Variants 2-8 encode the same isoform.
    Source sequence(s)
    BC096531, BQ443868, BY111208
    Consensus CDS
    CCDS23238.1
    UniProtKB/Swiss-Prot
    C8XPY9, Q5RKR3, Q6ZPQ3
    Related
    ENSMUSP00000129328.2, ENSMUST00000165276.2
    Conserved Domains (6) summary
    TIGR00864
    Location:154 → 228
    PCC; polycystin cation channel protein
    sd00033
    Location:36 → 52
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:99 → 159
    LRR_8; Leucine rich repeat
    pfam13927
    Location:232 → 360
    Ig_3; Immunoglobulin domain
    cd00096
    Location:256 → 263
    Ig; Ig strand B [structural motif]
    cl11960
    Location:351 → 373
    Ig; Immunoglobulin domain

  7. NM_001161541.1 → NP_001155013.1  immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform b precursor

    See identical proteins and their annotated locations for NP_001155013.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream translational start codon, compared to variant 1. The encoded isoform (b) is shorter than isoform a. Variants 2-8 encode the same isoform.
    Source sequence(s)
    BB611833, BC096531
    Consensus CDS
    CCDS23238.1
    UniProtKB/Swiss-Prot
    C8XPY9, Q5RKR3, Q6ZPQ3
    Related
    ENSMUSP00000109781.3, ENSMUST00000114144.9
    Conserved Domains (6) summary
    TIGR00864
    Location:154 → 228
    PCC; polycystin cation channel protein
    sd00033
    Location:36 → 52
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:99 → 159
    LRR_8; Leucine rich repeat
    pfam13927
    Location:232 → 360
    Ig_3; Immunoglobulin domain
    cd00096
    Location:256 → 263
    Ig; Ig strand B [structural motif]
    cl11960
    Location:351 → 373
    Ig; Immunoglobulin domain

  8. NM_177193.5 → NP_796167.2  immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform b precursor

    See identical proteins and their annotated locations for NP_796167.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream translational start codon, compared to variant 1. The encoded isoform (b) is shorter than isoform a. Variants 2-8 encode the same isoform.
    Source sequence(s)
    BC059068, BY079125, CA328406
    Consensus CDS
    CCDS23238.1
    UniProtKB/Swiss-Prot
    C8XPY9, Q5RKR3, Q6ZPQ3
    Related
    ENSMUSP00000149095.2, ENSMUST00000215950.2
    Conserved Domains (6) summary
    TIGR00864
    Location:154 → 228
    PCC; polycystin cation channel protein
    sd00033
    Location:36 → 52
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:99 → 159
    LRR_8; Leucine rich repeat
    pfam13927
    Location:232 → 360
    Ig_3; Immunoglobulin domain
    cd00096
    Location:256 → 263
    Ig; Ig strand B [structural motif]
    cl11960
    Location:351 → 373
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    58103580..58113563 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036155062.1 → XP_036010955.1  immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform X1

    UniProtKB/Swiss-Prot
    C8XPY9, Q5RKR3, Q6ZPQ3
    Conserved Domains (6) summary
    TIGR00864
    Location:154 → 228
    PCC; polycystin cation channel protein
    sd00033
    Location:36 → 52
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:99 → 159
    LRR_8; Leucine rich repeat
    pfam13927
    Location:232 → 360
    Ig_3; Immunoglobulin domain
    cd00096
    Location:256 → 263
    Ig; Ig strand B [structural motif]
    cl11960
    Location:351 → 373
    Ig; Immunoglobulin domain

  2. XM_036155064.1 → XP_036010957.1  immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform X1

    UniProtKB/Swiss-Prot
    C8XPY9, Q5RKR3, Q6ZPQ3
    Conserved Domains (6) summary
    TIGR00864
    Location:154 → 228
    PCC; polycystin cation channel protein
    sd00033
    Location:36 → 52
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:99 → 159
    LRR_8; Leucine rich repeat
    pfam13927
    Location:232 → 360
    Ig_3; Immunoglobulin domain
    cd00096
    Location:256 → 263
    Ig; Ig strand B [structural motif]
    cl11960
    Location:351 → 373
    Ig; Immunoglobulin domain

  3. XM_036155061.1 → XP_036010954.1  immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform X1

    UniProtKB/Swiss-Prot
    C8XPY9, Q5RKR3, Q6ZPQ3
    Conserved Domains (6) summary
    TIGR00864
    Location:154 → 228
    PCC; polycystin cation channel protein
    sd00033
    Location:36 → 52
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:99 → 159
    LRR_8; Leucine rich repeat
    pfam13927
    Location:232 → 360
    Ig_3; Immunoglobulin domain
    cd00096
    Location:256 → 263
    Ig; Ig strand B [structural motif]
    cl11960
    Location:351 → 373
    Ig; Immunoglobulin domain

  4. XM_030244418.2 → XP_030100278.1  immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform X1

    UniProtKB/Swiss-Prot
    C8XPY9, Q5RKR3, Q6ZPQ3
    Conserved Domains (6) summary
    TIGR00864
    Location:154 → 228
    PCC; polycystin cation channel protein
    sd00033
    Location:36 → 52
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:99 → 159
    LRR_8; Leucine rich repeat
    pfam13927
    Location:232 → 360
    Ig_3; Immunoglobulin domain
    cd00096
    Location:256 → 263
    Ig; Ig strand B [structural motif]
    cl11960
    Location:351 → 373
    Ig; Immunoglobulin domain

  5. XM_006511230.3 → XP_006511293.1  immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006511293.1

    UniProtKB/Swiss-Prot
    C8XPY9, Q5RKR3, Q6ZPQ3
    Conserved Domains (6) summary
    TIGR00864
    Location:154 → 228
    PCC; polycystin cation channel protein
    sd00033
    Location:36 → 52
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:99 → 159
    LRR_8; Leucine rich repeat
    pfam13927
    Location:232 → 360
    Ig_3; Immunoglobulin domain
    cd00096
    Location:256 → 263
    Ig; Ig strand B [structural motif]
    cl11960
    Location:351 → 373
    Ig; Immunoglobulin domain

  6. XM_036155065.1 → XP_036010958.1  immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform X1

    UniProtKB/Swiss-Prot
    C8XPY9, Q5RKR3, Q6ZPQ3
    Conserved Domains (6) summary
    TIGR00864
    Location:154 → 228
    PCC; polycystin cation channel protein
    sd00033
    Location:36 → 52
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:99 → 159
    LRR_8; Leucine rich repeat
    pfam13927
    Location:232 → 360
    Ig_3; Immunoglobulin domain
    cd00096
    Location:256 → 263
    Ig; Ig strand B [structural motif]
    cl11960
    Location:351 → 373
    Ig; Immunoglobulin domain

  7. XM_006511229.4 → XP_006511292.1  immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006511292.1

    UniProtKB/Swiss-Prot
    C8XPY9, Q5RKR3, Q6ZPQ3
    Conserved Domains (6) summary
    TIGR00864
    Location:154 → 228
    PCC; polycystin cation channel protein
    sd00033
    Location:36 → 52
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:99 → 159
    LRR_8; Leucine rich repeat
    pfam13927
    Location:232 → 360
    Ig_3; Immunoglobulin domain
    cd00096
    Location:256 → 263
    Ig; Ig strand B [structural motif]
    cl11960
    Location:351 → 373
    Ig; Immunoglobulin domain

  8. XM_006511232.4 → XP_006511295.1  immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006511295.1

    UniProtKB/Swiss-Prot
    C8XPY9, Q5RKR3, Q6ZPQ3
    Conserved Domains (6) summary
    TIGR00864
    Location:154 → 228
    PCC; polycystin cation channel protein
    sd00033
    Location:36 → 52
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:99 → 159
    LRR_8; Leucine rich repeat
    pfam13927
    Location:232 → 360
    Ig_3; Immunoglobulin domain
    cd00096
    Location:256 → 263
    Ig; Ig strand B [structural motif]
    cl11960
    Location:351 → 373
    Ig; Immunoglobulin domain

  9. XM_030244417.1 → XP_030100277.1  immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform X1

    UniProtKB/Swiss-Prot
    C8XPY9, Q5RKR3, Q6ZPQ3
    Conserved Domains (6) summary
    TIGR00864
    Location:154 → 228
    PCC; polycystin cation channel protein
    sd00033
    Location:36 → 52
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:99 → 159
    LRR_8; Leucine rich repeat
    pfam13927
    Location:232 → 360
    Ig_3; Immunoglobulin domain
    cd00096
    Location:256 → 263
    Ig; Ig strand B [structural motif]
    cl11960
    Location:351 → 373
    Ig; Immunoglobulin domain

  10. XM_006511231.5 → XP_006511294.1  immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006511294.1

    UniProtKB/Swiss-Prot
    C8XPY9, Q5RKR3, Q6ZPQ3
    Conserved Domains (6) summary
    TIGR00864
    Location:154 → 228
    PCC; polycystin cation channel protein
    sd00033
    Location:36 → 52
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:99 → 159
    LRR_8; Leucine rich repeat
    pfam13927
    Location:232 → 360
    Ig_3; Immunoglobulin domain
    cd00096
    Location:256 → 263
    Ig; Ig strand B [structural motif]
    cl11960
    Location:351 → 373
    Ig; Immunoglobulin domain

  11. XM_006511234.5 → XP_006511297.1  immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006511297.1

    UniProtKB/Swiss-Prot
    C8XPY9, Q5RKR3, Q6ZPQ3
    Conserved Domains (6) summary
    TIGR00864
    Location:154 → 228
    PCC; polycystin cation channel protein
    sd00033
    Location:36 → 52
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:99 → 159
    LRR_8; Leucine rich repeat
    pfam13927
    Location:232 → 360
    Ig_3; Immunoglobulin domain
    cd00096
    Location:256 → 263
    Ig; Ig strand B [structural motif]
    cl11960
    Location:351 → 373
    Ig; Immunoglobulin domain

  12. XM_030244419.2 → XP_030100279.1  immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform X1

    UniProtKB/Swiss-Prot
    C8XPY9, Q5RKR3, Q6ZPQ3
    Conserved Domains (6) summary
    TIGR00864
    Location:154 → 228
    PCC; polycystin cation channel protein
    sd00033
    Location:36 → 52
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:99 → 159
    LRR_8; Leucine rich repeat
    pfam13927
    Location:232 → 360
    Ig_3; Immunoglobulin domain
    cd00096
    Location:256 → 263
    Ig; Ig strand B [structural motif]
    cl11960
    Location:351 → 373
    Ig; Immunoglobulin domain

  13. XM_036155063.1 → XP_036010956.1  immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform X1

    UniProtKB/Swiss-Prot
    C8XPY9, Q5RKR3, Q6ZPQ3
    Conserved Domains (6) summary
    TIGR00864
    Location:154 → 228
    PCC; polycystin cation channel protein
    sd00033
    Location:36 → 52
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:99 → 159
    LRR_8; Leucine rich repeat
    pfam13927
    Location:232 → 360
    Ig_3; Immunoglobulin domain
    cd00096
    Location:256 → 263
    Ig; Ig strand B [structural motif]
    cl11960
    Location:351 → 373
    Ig; Immunoglobulin domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5RKR3.1 GenPept UniProtKB/Swiss-Prot:Q5RKR3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous