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Ccdc171 coiled-coil domain containing 171 [ Mus musculus (house mouse) ]

Gene ID: 320226, updated on 5-Mar-2024

Summary

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Official Symbol
Ccdc171provided by MGI
Official Full Name
coiled-coil domain containing 171provided by MGI
Primary source
MGI:MGI:1922152
See related
Ensembl:ENSMUSG00000052407 AllianceGenome:MGI:1922152
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4930418J05Rik; 4930473A06Rik; A330015D16Rik
Summary
Is expressed in olfactory epithelium and trigeminal ganglion. Orthologous to human CCDC171 (coiled-coil domain containing 171). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis adult (RPKM 4.5), CNS E14 (RPKM 1.2) and 16 other tissues See more
Orthologs
human all
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Genomic context

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Location:
4 C3; 4 39.46 cM
Exon count:
29
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (83443649..83784380)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (83525409..83866143)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E10238 Neighboring gene ribosomal protein L34 pseudogene Neighboring gene predicted gene, 42308 Neighboring gene predicted gene, 25899 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:83213711-83213898 Neighboring gene DDB1 and CUL4 associated factor 12 pseudogene Neighboring gene chromobox 3, pseudogene 3 Neighboring gene predicted gene, 42309 Neighboring gene predicted gene 11415 Neighboring gene STARR-seq mESC enhancer starr_10651 Neighboring gene RIKEN cDNA 6030471H07 gene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
  2. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
  3. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Chemically induced (ENU) (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
coiled-coil domain-containing protein 171

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355378.1 → NP_001342307.1  coiled-coil domain-containing protein 171 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL928772, BB617255, BX682545, BX936355, BY715112, CD552966, CF915271, CJ055245
    Consensus CDS
    CCDS89772.1
    UniProtKB/Swiss-Prot
    E9Q1U1, Q8BLX2
    Related
    ENSMUSP00000155912.2, ENSMUST00000231339.2
    Conserved Domains (2) summary
    COG1196
    Location:464 → 1198
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:58 → 818
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  2. NM_001355549.1 → NP_001342478.1  coiled-coil domain-containing protein 171 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AK015563, AL928772, BB617255, BX682545, BX936355, CD552966, CF915271, CJ055245
    Conserved Domains (1) summary
    cl25732
    Location:8 → 648
    SMC_N; RecF/RecN/SMC N terminal domain

  3. NM_001369172.1 → NP_001356101.1  coiled-coil domain-containing protein 171 isoform 3

    Status: VALIDATED

    Source sequence(s)
    BX682545
    Conserved Domains (1) summary
    TIGR01843
    Location:33 → 149
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family

  4. NM_001369173.1 → NP_001356102.1  coiled-coil domain-containing protein 171 isoform 4

    Status: VALIDATED

    Source sequence(s)
    BX682545
    Consensus CDS
    CCDS89771.1
    UniProtKB/TrEMBL
    S4R1F3
    Related
    ENSMUSP00000138195.2, ENSMUST00000126429.8
    Conserved Domains (1) summary
    PRK09039
    Location:50 → 117
    PRK09039; hypothetical protein; Validated

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    83443649..83784380
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006537992.4 → XP_006538055.1  coiled-coil domain-containing protein 171 isoform X4

    UniProtKB/Swiss-Prot
    E9Q1U1, Q8BLX2
    Conserved Domains (2) summary
    COG1196
    Location:464 → 1198
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:58 → 731
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  2. XM_006537991.4 → XP_006538054.1  coiled-coil domain-containing protein 171 isoform X3

    UniProtKB/Swiss-Prot
    E9Q1U1, Q8BLX2
    Conserved Domains (2) summary
    COG1196
    Location:485 → 1204
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:58 → 818
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  3. XM_006537990.5 → XP_006538053.1  coiled-coil domain-containing protein 171 isoform X2

    UniProtKB/Swiss-Prot
    E9Q1U1, Q8BLX2
    Conserved Domains (2) summary
    COG1196
    Location:420 → 1154
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:58 → 774
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  4. XM_006537993.5 → XP_006538056.1  coiled-coil domain-containing protein 171 isoform X5

    Conserved Domains (2) summary
    COG1196
    Location:152 → 1032
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:64 → 213
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  5. XM_006537989.5 → XP_006538052.1  coiled-coil domain-containing protein 171 isoform X1

    See identical proteins and their annotated locations for XP_006538052.1

    UniProtKB/Swiss-Prot
    E9Q1U1, Q8BLX2
    Related
    ENSMUSP00000056520.7, ENSMUST00000053414.13
    Conserved Domains (2) summary
    COG1196
    Location:464 → 1198
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:58 → 818
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001081012.1: Suppressed sequence

    Description
    NM_001081012.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.

  2. NM_029117.1: Suppressed sequence

    Description
    NM_029117.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.

  3. NM_177108.2: Suppressed sequence

    Description
    NM_177108.2: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
E9Q1U1.1 GenPept UniProtKB/Swiss-Prot:E9Q1U1

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