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Catsperg1 cation channel sperm associated auxiliary subunit gamma 1 [ Mus musculus (house mouse) ]

Gene ID: 320225, updated on 11-Apr-2024

Summary

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Official Symbol
Catsperg1provided by MGI
Official Full Name
cation channel sperm associated auxiliary subunit gamma 1provided by MGI
Primary source
MGI:MGI:2443617
See related
Ensembl:ENSMUSG00000049676 AllianceGenome:MGI:2443617
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Catsperg; A230107C01Rik
Summary
Predicted to be located in membrane and sperm principal piece. Predicted to be integral component of membrane. Predicted to be part of CatSper complex. Predicted to be active in motile cilium. Orthologous to human CATSPERG (cation channel sperm associated auxiliary subunit gamma). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 64.0) and CNS E18 (RPKM 1.6) See more
Orthologs
human all
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Genomic context

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See Catsperg1 in Genome Data Viewer
Location:
7 B1; 7 16.94 cM
Exon count:
33
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (28880957..28915013, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (29181532..29215589, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene gametogenetin Neighboring gene STARR-positive B cell enhancer ABC_E1337 Neighboring gene proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 Neighboring gene STARR-positive B cell enhancer ABC_E10433 Neighboring gene STARR-positive B cell enhancer ABC_E4913 Neighboring gene STARR-seq mESC enhancer starr_18461 Neighboring gene potassium inwardly-rectifying channel, subfamily K, member 6 Neighboring gene STARR-positive B cell enhancer ABC_E544 Neighboring gene Yip1 interacting factor homolog B (S. cerevisiae) Neighboring gene RIKEN cDNA 2200002D01 gene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A novel, single, transmembrane protein CATSPERG is associated with CATSPER1 channel protein. Wang H, et al. Biol Reprod, 2009 Sep. PMID 19516020, Free PMC Article
  2. A novel gene required for male fertility and functional CATSPER channel formation in spermatozoa. Chung JJ, et al. Nat Commun, 2011 Jan 11. PMID 21224844, Free PMC Article
  3. A germline-specific class of small RNAs binds mammalian Piwi proteins. Girard A, et al. Nature, 2006 Jul 13. PMID 16751776
  4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
part_of CatSper complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in motile cilium IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in sperm principal piece IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cation channel sperm-associated protein subunit gamma 1
Names
cation channel, sperm-associated, gamma 1
catsper channel auxiliary subunit gamma 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164658.1 → NP_001158130.1  cation channel sperm-associated protein subunit gamma 1 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AK133307, AV277263, BB633050
    Consensus CDS
    CCDS52170.1
    UniProtKB/Swiss-Prot
    E9Q355
    Related
    ENSMUSP00000045233.7, ENSMUST00000047846.13
    Conserved Domains (1) summary
    pfam15064
    Location:13 → 919
    CATSPERG; Cation channel sperm-associated protein subunit gamma

  2. NM_001368407.1 → NP_001355336.1  cation channel sperm-associated protein subunit gamma 1 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC164564
    Consensus CDS
    CCDS90197.1
    UniProtKB/Swiss-Prot
    E9PW02, E9Q355, E9QAY8, Q3V0A1, Q8C9D6, Q8CAA4, Q8R5F0
    Conserved Domains (1) summary
    pfam15064
    Location:7 → 973
    CATSPERG; Cation channel sperm-associated protein subunit gamma

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    28880957..28915013 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006540090.4 → XP_006540153.1  cation channel sperm-associated protein subunit gamma 1 isoform X15

    Conserved Domains (1) summary
    pfam15064
    Location:59 → 1025
    CATSPERG; Cation channel sperm-associated protein subunit gamma

  2. XM_006540091.4 → XP_006540154.1  cation channel sperm-associated protein subunit gamma 1 isoform X16

    See identical proteins and their annotated locations for XP_006540154.1

    UniProtKB/Swiss-Prot
    E9PW02, E9Q355, E9QAY8, Q3V0A1, Q8C9D6, Q8CAA4, Q8R5F0
    Related
    ENSMUSP00000129837.2, ENSMUST00000169143.8
    Conserved Domains (1) summary
    pfam15064
    Location:7 → 973
    CATSPERG; Cation channel sperm-associated protein subunit gamma

  3. XM_006540094.4 → XP_006540157.1  cation channel sperm-associated protein subunit gamma 1 isoform X19

    Conserved Domains (1) summary
    pfam15064
    Location:7 → 806
    CATSPERG; Cation channel sperm-associated protein subunit gamma

  4. XM_006540080.2 → XP_006540143.1  cation channel sperm-associated protein subunit gamma 1 isoform X7

    Conserved Domains (2) summary
    pfam03157
    Location:150 → 677
    Glutenin_hmw; High molecular weight glutenin subunit
    pfam15064
    Location:733 → 1646
    CATSPERG; Cation channel sperm-associated protein subunit gamma

  5. XM_017322301.2 → XP_017177790.1  cation channel sperm-associated protein subunit gamma 1 isoform X2

    Conserved Domains (2) summary
    pfam03157
    Location:150 → 677
    Glutenin_hmw; High molecular weight glutenin subunit
    pfam15064
    Location:733 → 1681
    CATSPERG; Cation channel sperm-associated protein subunit gamma

  6. XM_006540083.2 → XP_006540146.1  cation channel sperm-associated protein subunit gamma 1 isoform X11

    Conserved Domains (2) summary
    pfam03157
    Location:150 → 677
    Glutenin_hmw; High molecular weight glutenin subunit
    pfam15064
    Location:733 → 1523
    CATSPERG; Cation channel sperm-associated protein subunit gamma

  7. XM_006540076.2 → XP_006540139.1  cation channel sperm-associated protein subunit gamma 1 isoform X3

    Conserved Domains (2) summary
    pfam03157
    Location:150 → 677
    Glutenin_hmw; High molecular weight glutenin subunit
    pfam15064
    Location:733 → 1679
    CATSPERG; Cation channel sperm-associated protein subunit gamma

  8. XM_030242677.1 → XP_030098537.1  cation channel sperm-associated protein subunit gamma 1 isoform X9

    Conserved Domains (2) summary
    pfam03157
    Location:150 → 677
    Glutenin_hmw; High molecular weight glutenin subunit
    pfam15064
    Location:733 → 1610
    CATSPERG; Cation channel sperm-associated protein subunit gamma

  9. XM_006540078.2 → XP_006540141.1  cation channel sperm-associated protein subunit gamma 1 isoform X5

    Conserved Domains (2) summary
    pfam03157
    Location:150 → 677
    Glutenin_hmw; High molecular weight glutenin subunit
    pfam15064
    Location:733 → 1663
    CATSPERG; Cation channel sperm-associated protein subunit gamma

  10. XM_006540081.3 → XP_006540144.1  cation channel sperm-associated protein subunit gamma 1 isoform X8

    Conserved Domains (2) summary
    pfam03157
    Location:150 → 677
    Glutenin_hmw; High molecular weight glutenin subunit
    pfam15064
    Location:733 → 1669
    CATSPERG; Cation channel sperm-associated protein subunit gamma

  11. XM_006540077.2 → XP_006540140.1  cation channel sperm-associated protein subunit gamma 1 isoform X4

    Conserved Domains (2) summary
    pfam03157
    Location:150 → 677
    Glutenin_hmw; High molecular weight glutenin subunit
    pfam15064
    Location:733 → 1699
    CATSPERG; Cation channel sperm-associated protein subunit gamma

  12. XM_006540074.2 → XP_006540137.1  cation channel sperm-associated protein subunit gamma 1 isoform X1

    Conserved Domains (2) summary
    pfam03157
    Location:150 → 677
    Glutenin_hmw; High molecular weight glutenin subunit
    pfam15064
    Location:733 → 1699
    CATSPERG; Cation channel sperm-associated protein subunit gamma

  13. XM_006540086.2 → XP_006540149.1  cation channel sperm-associated protein subunit gamma 1 isoform X13

    Conserved Domains (2) summary
    pfam03157
    Location:150 → 677
    Glutenin_hmw; High molecular weight glutenin subunit
    pfam15064
    Location:782 → 1479
    CATSPERG; Cation channel sperm-associated protein subunit gamma

  14. XM_006540085.2 → XP_006540148.1  cation channel sperm-associated protein subunit gamma 1 isoform X12

    Conserved Domains (2) summary
    pfam03157
    Location:150 → 677
    Glutenin_hmw; High molecular weight glutenin subunit
    pfam15064
    Location:733 → 1514
    CATSPERG; Cation channel sperm-associated protein subunit gamma

  15. XM_006540082.2 → XP_006540145.1  cation channel sperm-associated protein subunit gamma 1 isoform X10

    Conserved Domains (2) summary
    pfam03157
    Location:150 → 677
    Glutenin_hmw; High molecular weight glutenin subunit
    pfam15064
    Location:733 → 1532
    CATSPERG; Cation channel sperm-associated protein subunit gamma

  16. XM_006540079.3 → XP_006540142.1  cation channel sperm-associated protein subunit gamma 1 isoform X6

    Conserved Domains (2) summary
    pfam03157
    Location:150 → 677
    Glutenin_hmw; High molecular weight glutenin subunit
    pfam15064
    Location:733 → 1646
    CATSPERG; Cation channel sperm-associated protein subunit gamma

  17. XM_011250601.2 → XP_011248903.1  cation channel sperm-associated protein subunit gamma 1 isoform X14

    See identical proteins and their annotated locations for XP_011248903.1

    Conserved Domains (2) summary
    pfam03157
    Location:150 → 677
    Glutenin_hmw; High molecular weight glutenin subunit
    pfam15064
    Location:733 → 1593
    CATSPERG; Cation channel sperm-associated protein subunit gamma

  18. XM_011250600.2 → XP_011248902.1  cation channel sperm-associated protein subunit gamma 1 isoform X14

    See identical proteins and their annotated locations for XP_011248902.1

    Conserved Domains (2) summary
    pfam03157
    Location:150 → 677
    Glutenin_hmw; High molecular weight glutenin subunit
    pfam15064
    Location:733 → 1593
    CATSPERG; Cation channel sperm-associated protein subunit gamma

  19. XM_030242678.1 → XP_030098538.1  cation channel sperm-associated protein subunit gamma 1 isoform X18

    Conserved Domains (3) summary
    PRK12678
    Location:81 → 318
    PRK12678; transcription termination factor Rho; Provisional
    pfam08017
    Location:352 → 666
    Fibrinogen_BP; Fibrinogen binding protein
    pfam15064
    Location:733 → 964
    CATSPERG; Cation channel sperm-associated protein subunit gamma

  20. XM_006540092.5 → XP_006540155.1  cation channel sperm-associated protein subunit gamma 1 isoform X17

    See identical proteins and their annotated locations for XP_006540155.1

    Conserved Domains (3) summary
    PRK12678
    Location:81 → 318
    PRK12678; transcription termination factor Rho; Provisional
    pfam08017
    Location:352 → 666
    Fibrinogen_BP; Fibrinogen binding protein
    pfam15064
    Location:733 → 956
    CATSPERG; Cation channel sperm-associated protein subunit gamma

RNA

  1. XR_003946491.1 RNA Sequence

  2. XR_003946492.1 RNA Sequence

  3. XR_003946493.1 RNA Sequence

  4. XR_001785574.3 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001039721.2: Suppressed sequence

    Description
    NM_001039721.2: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
E9Q355.1 GenPept UniProtKB/Swiss-Prot:E9Q355

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