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Lrrc58 leucine rich repeat containing 58 [ Mus musculus (house mouse) ]

Gene ID: 320184, updated on 5-Mar-2024

Summary

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Official Symbol
Lrrc58provided by MGI
Official Full Name
leucine rich repeat containing 58provided by MGI
Primary source
MGI:MGI:2443542
See related
Ensembl:ENSMUSG00000034158 AllianceGenome:MGI:2443542
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1810012N18Rik; C330018J07Rik
Summary
Orthologous to human LRRC58 (leucine rich repeat containing 58). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 37.6), subcutaneous fat pad adult (RPKM 32.2) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
16 B3; 16 26.49 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (37688762..37709219)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (37868400..37888857)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene follistatin-like 1 Neighboring gene STARR-seq mESC enhancer starr_40798 Neighboring gene predicted gene, 41452 Neighboring gene butyrophilin-like 12 Neighboring gene VISTA enhancer mm1361 Neighboring gene actin, beta, cytoplasmic (Actb) pseudogene Neighboring gene STARR-seq mESC enhancer starr_40799 Neighboring gene G protein-coupled receptor 156 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:37963429-37963630 Neighboring gene predicted gene, 36225 Neighboring gene predicted gene, 25140 Neighboring gene STARR-seq mESC enhancer starr_40800 Neighboring gene RIKEN cDNA 4930542C21 gene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt. Murn J, et al. Genes Dev, 2015 Mar 1. PMID 25737280, Free PMC Article
  2. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
leucine-rich repeat-containing protein 58

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177093.3 → NP_796067.2  leucine-rich repeat-containing protein 58

    See identical proteins and their annotated locations for NP_796067.2

    Status: VALIDATED

    Source sequence(s)
    AC161268, AK049274
    Consensus CDS
    CCDS37340.1
    UniProtKB/Swiss-Prot
    B2RU81, Q3UGP9, Q8BX06
    Related
    ENSMUSP00000077779.7, ENSMUST00000078717.7
    Conserved Domains (3) summary
    cd00116
    Location:54 → 206
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:65 → 87
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:161 → 219
    LRR_8; Leucine rich repeat

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    37688762..37709219
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3UGP9.1 GenPept UniProtKB/Swiss-Prot:Q3UGP9

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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