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Zmat4 zinc finger, matrin type 4 [ Mus musculus (house mouse) ]

Gene ID: 320158, updated on 5-Mar-2024

Summary

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Official Symbol
Zmat4provided by MGI
Official Full Name
zinc finger, matrin type 4provided by MGI
Primary source
MGI:MGI:2443497
See related
Ensembl:ENSMUSG00000037492 AllianceGenome:MGI:2443497
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9630048M01Rik
Summary
Predicted to enable identical protein binding activity. Predicted to be located in nucleus. Is expressed in jaw; nervous system; sensory organ; and urethra. Orthologous to human ZMAT4 (zinc finger matrin-type 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in cortex adult (RPKM 4.2), frontal lobe adult (RPKM 3.6) and 6 other tissues See more
Orthologs
human all
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Genomic context

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See Zmat4 in Genome Data Viewer
Location:
8 A2; 8 11.5 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (24137347..24553133)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (23647326..24063117)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene secreted frizzled-related protein 1 Neighboring gene RIKEN cDNA 4930413E20 gene Neighboring gene STARR-seq mESC enhancer starr_20923 Neighboring gene STARR-seq mESC enhancer starr_20924 Neighboring gene STARR-seq mESC enhancer starr_20925 Neighboring gene STARR-seq mESC enhancer starr_20926 Neighboring gene STARR-seq mESC enhancer starr_20927 Neighboring gene predicted gene, 30471 Neighboring gene STARR-seq mESC enhancer starr_20929 Neighboring gene STARR-seq mESC enhancer starr_20931 Neighboring gene STARR-seq mESC enhancer starr_20932 Neighboring gene STARR-seq mESC enhancer starr_20933 Neighboring gene predicted gene, 51564 Neighboring gene STARR-seq mESC enhancer starr_20934 Neighboring gene predicted gene, 57528 Neighboring gene STARR-seq mESC enhancer starr_20935 Neighboring gene STARR-seq mESC enhancer starr_20936 Neighboring gene predicted gene, 30633

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Sall1 balances self-renewal and differentiation of renal progenitor cells. Basta JM, et al. Development, 2014 Mar. PMID 24550112, Free PMC Article
  2. The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex. Schilling K, et al. Cerebellum, 2009 Dec. PMID 19554387
  3. Genomic analysis of mouse retinal development. Blackshaw S, et al. PLoS Biol, 2004 Sep. PMID 15226823, Free PMC Article
  4. A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Thompson CL, et al. Neuron, 2014 Jul 16. PMID 24952961, Free PMC Article
  5. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC90808

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger matrin-type protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001277239.1 → NP_001264168.1  zinc finger matrin-type protein 4 isoform 2

    See identical proteins and their annotated locations for NP_001264168.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an alternate internal exon compared to variant 1, that causes translation to begin from a downstream AUG. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AK036254, AK140413, BC079657, BQ174274
    Consensus CDS
    CCDS85514.1
    UniProtKB/Swiss-Prot
    Q8BZ94
    Related
    ENSMUSP00000146734.2, ENSMUST00000207301.2
    Conserved Domains (3) summary
    smart00451
    Location:73 → 107
    ZnF_U1; U1-like zinc finger
    COG5246
    Location:96 → 160
    PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
    sd00020
    Location:78 → 100
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. NM_177086.4 → NP_796060.1  zinc finger matrin-type protein 4 isoform 1

    See identical proteins and their annotated locations for NP_796060.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AK036254, AK140413, BQ174274
    Consensus CDS
    CCDS22192.1
    UniProtKB/Swiss-Prot
    Q3USG2, Q6AXC5, Q8BZ94
    Related
    ENSMUSP00000049430.5, ENSMUST00000042352.11
    Conserved Domains (3) summary
    smart00451
    Location:142 → 176
    ZnF_U1; U1-like zinc finger
    COG5246
    Location:165 → 229
    PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
    sd00020
    Location:147 → 169
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    24137347..24553133
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017312858.3 → XP_017168347.1  zinc finger matrin-type protein 4 isoform X2

    UniProtKB/Swiss-Prot
    Q3USG2, Q6AXC5, Q8BZ94
    Conserved Domains (3) summary
    smart00451
    Location:142 → 176
    ZnF_U1; U1-like zinc finger
    COG5246
    Location:165 → 229
    PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
    sd00020
    Location:147 → 169
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. XM_006509141.3 → XP_006509204.1  zinc finger matrin-type protein 4 isoform X2

    See identical proteins and their annotated locations for XP_006509204.1

    UniProtKB/Swiss-Prot
    Q3USG2, Q6AXC5, Q8BZ94
    Conserved Domains (3) summary
    smart00451
    Location:142 → 176
    ZnF_U1; U1-like zinc finger
    COG5246
    Location:165 → 229
    PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
    sd00020
    Location:147 → 169
    ZF_C2H2; C2H2 Zn finger [structural motif]

  3. XM_006509140.4 → XP_006509203.1  zinc finger matrin-type protein 4 isoform X2

    See identical proteins and their annotated locations for XP_006509203.1

    UniProtKB/Swiss-Prot
    Q3USG2, Q6AXC5, Q8BZ94
    Conserved Domains (3) summary
    smart00451
    Location:142 → 176
    ZnF_U1; U1-like zinc finger
    COG5246
    Location:165 → 229
    PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
    sd00020
    Location:147 → 169
    ZF_C2H2; C2H2 Zn finger [structural motif]

  4. XM_030243610.1 → XP_030099470.1  zinc finger matrin-type protein 4 isoform X1

    Conserved Domains (3) summary
    smart00451
    Location:156 → 190
    ZnF_U1; U1-like zinc finger
    COG5246
    Location:179 → 243
    PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
    sd00020
    Location:161 → 183
    ZF_C2H2; C2H2 Zn finger [structural motif]

  5. XM_011242142.3 → XP_011240444.1  zinc finger matrin-type protein 4 isoform X2

    See identical proteins and their annotated locations for XP_011240444.1

    UniProtKB/Swiss-Prot
    Q3USG2, Q6AXC5, Q8BZ94
    Conserved Domains (3) summary
    smart00451
    Location:142 → 176
    ZnF_U1; U1-like zinc finger
    COG5246
    Location:165 → 229
    PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
    sd00020
    Location:147 → 169
    ZF_C2H2; C2H2 Zn finger [structural motif]

  6. XM_011242141.3 → XP_011240443.1  zinc finger matrin-type protein 4 isoform X2

    See identical proteins and their annotated locations for XP_011240443.1

    UniProtKB/Swiss-Prot
    Q3USG2, Q6AXC5, Q8BZ94
    Conserved Domains (3) summary
    smart00451
    Location:142 → 176
    ZnF_U1; U1-like zinc finger
    COG5246
    Location:165 → 229
    PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
    sd00020
    Location:147 → 169
    ZF_C2H2; C2H2 Zn finger [structural motif]

  7. XM_006509139.5 → XP_006509202.1  zinc finger matrin-type protein 4 isoform X1

    Conserved Domains (3) summary
    smart00451
    Location:156 → 190
    ZnF_U1; U1-like zinc finger
    COG5246
    Location:179 → 243
    PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
    sd00020
    Location:161 → 183
    ZF_C2H2; C2H2 Zn finger [structural motif]

  8. XM_030243611.2 → XP_030099471.1  zinc finger matrin-type protein 4 isoform X1

    Conserved Domains (3) summary
    smart00451
    Location:156 → 190
    ZnF_U1; U1-like zinc finger
    COG5246
    Location:179 → 243
    PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
    sd00020
    Location:161 → 183
    ZF_C2H2; C2H2 Zn finger [structural motif]

  9. XM_006509142.5 → XP_006509205.1  zinc finger matrin-type protein 4 isoform X3

    Conserved Domains (3) summary
    smart00451
    Location:96 → 130
    ZnF_U1; U1-like zinc finger
    COG5246
    Location:119 → 183
    PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
    sd00020
    Location:101 → 123
    ZF_C2H2; C2H2 Zn finger [structural motif]

  10. XM_030243612.2 → XP_030099472.1  zinc finger matrin-type protein 4 isoform X4

    Conserved Domains (3) summary
    smart00451
    Location:73 → 107
    ZnF_U1; U1-like zinc finger
    COG5246
    Location:96 → 160
    PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
    sd00020
    Location:78 → 100
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BZ94.1 GenPept UniProtKB/Swiss-Prot:Q8BZ94

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