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Dgki diacylglycerol kinase, iota [ Mus musculus (house mouse) ]

Gene ID: 320127, updated on 21-Apr-2024

Summary

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Official Symbol
Dgkiprovided by MGI
Official Full Name
diacylglycerol kinase, iotaprovided by MGI
Primary source
MGI:MGI:2443430
See related
Ensembl:ENSMUSG00000038665 AllianceGenome:MGI:2443430
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
6430604M11Rik; C130010K08Rik
Summary
Enables GTPase inhibitor activity; diacylglycerol kinase activity; and small GTPase binding activity. Involved in regulation of synaptic vesicle exocytosis. Acts upstream of or within several processes, including chemical synaptic transmission; habituation; and modulation of chemical synaptic transmission. Located in Schaffer collateral - CA1 synapse; glutamatergic synapse; and perinuclear region of cytoplasm. Part of guanyl-nucleotide exchange factor complex. Is expressed in cerebral cortex; cerebral cortex mantle layer; and cerebral cortex marginal layer. Orthologous to human DGKI (diacylglycerol kinase iota). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in frontal lobe adult (RPKM 3.1), cortex adult (RPKM 2.4) and 8 other tissues See more
Orthologs
human all
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Genomic context

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Location:
6; 6 B1
Exon count:
37
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (36814316..37281034, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (36837381..37300955, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_15571 Neighboring gene predicted gene 2189 Neighboring gene STARR-seq mESC enhancer starr_15572 Neighboring gene pleiotrophin Neighboring gene predicted gene, 53282 Neighboring gene STARR-seq mESC enhancer starr_15573 Neighboring gene predicted gene, 52857 Neighboring gene STARR-seq mESC enhancer starr_15575 Neighboring gene predicted pseudogene 7452 Neighboring gene STARR-seq mESC enhancer starr_15579 Neighboring gene cAMP responsive element binding protein 3-like 2 Neighboring gene STARR-positive B cell enhancer mm9_chr6:37392120-37392421 Neighboring gene predicted gene, 33275 Neighboring gene predicted gene, 33318

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Enhanced histamine-induced itch in diacylglycerol kinase iota knockout mice. Bartsch VB, et al. PLoS One, 2019. PMID 31167004, Free PMC Article
  2. Mania- and anxiety-like behavior and impaired maternal care in female diacylglycerol kinase eta and iota double knockout mice. Bartsch VB, et al. Genes Brain Behav, 2020 Mar. PMID 30985063, Free PMC Article
  3. Exome Sequencing Identifies Genes and Gene Sets Contributing to Severe Childhood Obesity, Linking PHIP Variants to Repressed POMC Transcription. Marenne G, et al. Cell Metab, 2020 Jun 2. PMID 32492392, Free PMC Article
  4. Diacylglycerol kinase delta regulates protein kinase C and epidermal growth factor receptor signaling. Crotty T, et al. Proc Natl Acad Sci U S A, 2006 Oct 17. PMID 17021016, Free PMC Article
  5. Diacylglycerol kinase iota regulates Ras guanyl-releasing protein 3 and inhibits Rap1 signaling. Regier DS, et al. Proc Natl Acad Sci U S A, 2005 May 24. PMID 15894621, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Mania- and anxiety-like behavior and impaired maternal care in female diacylglycerol kinase eta and iota double knockout mice.
    Title: Mania- and anxiety-like behavior and impaired maternal care in female diacylglycerol kinase eta and iota double knockout mice.
  2. These data suggest Dgki regulates sensory neuron and behavioral responses to histamine.
    Title: Enhanced histamine-induced itch in diacylglycerol kinase iota knockout mice.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (1)  1 citation
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP-dependent diacylglycerol kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATP-dependent diacylglycerol kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables ATP-dependent diacylglycerol kinase activity ISO
Inferred from Sequence Orthology
more info
  
enables GTPase inhibitor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables GTPase inhibitor activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables small GTPase binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of Ras protein signal transduction IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in diacylglycerol metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in diacylglycerol metabolic process ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within excitatory postsynaptic potential IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within habituation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in lipid phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in lipid phosphorylation ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within neurotransmitter secretion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in phosphatidic acid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in phosphatidic acid biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of Ras protein signal transduction IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in presynaptic modulation of chemical synaptic transmission IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in presynaptic modulation of chemical synaptic transmission IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein kinase C-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of GTPase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of long-term synaptic depression IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of synaptic transmission, glutamatergic IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in Schaffer collateral - CA1 synapse IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in Schaffer collateral - CA1 synapse IMP
Inferred from Mutant Phenotype
more info
 PubMed 
located_in axon terminus ISO
Inferred from Sequence Orthology
more info
 PubMed 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 PubMed 
located_in dendritic spine ISO
Inferred from Sequence Orthology
more info
 PubMed 
located_in excitatory synapse ISO
Inferred from Sequence Orthology
more info
 PubMed 
is_active_in extrinsic component of postsynaptic density membrane ISO
Inferred from Sequence Orthology
more info
  
is_active_in extrinsic component of presynaptic active zone membrane ISO
Inferred from Sequence Orthology
more info
  
is_active_in glutamatergic synapse IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in glutamatergic synapse IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in glutamatergic synapse IMP
Inferred from Mutant Phenotype
more info
 PubMed 
is_active_in glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
  
part_of guanyl-nucleotide exchange factor complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
 PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  
located_in perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in postsynaptic density ISO
Inferred from Sequence Orthology
more info
 PubMed 
located_in presynapse IDA
Inferred from Direct Assay
more info
 PubMed 
located_in presynaptic active zone ISO
Inferred from Sequence Orthology
more info
 PubMed 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 PubMed 
located_in synapse ISO
Inferred from Sequence Orthology
more info
 PubMed 
located_in synaptic membrane ISO
Inferred from Sequence Orthology
more info
 PubMed 
is_active_in synaptic vesicle ISO
Inferred from Sequence Orthology
more info
  
located_in synaptic vesicle ISO
Inferred from Sequence Orthology
more info
 PubMed 

General protein information

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Preferred Names
diacylglycerol kinase iota
Names
DAG kinase iota
NP_001074675.1
NP_001334033.1
XP_006506321.1
XP_006506322.1
XP_011239687.1
XP_017177113.1
XP_017177114.1
XP_017177115.1
XP_017177116.1
XP_017177117.1
XP_017177118.1
XP_017177119.1
XP_017177121.1
XP_017177122.1
XP_030111313.1
XP_030111314.1
XP_036022113.1
XP_036022114.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081206.2 → NP_001074675.1  diacylglycerol kinase iota isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC154019, AC159480, AK081360
    Consensus CDS
    CCDS39459.1
    UniProtKB/Swiss-Prot
    D3YWQ0, D3Z2W1
    UniProtKB/TrEMBL
    D3Z519
    Related
    ENSMUSP00000099071.4, ENSMUST00000101532.10
    Conserved Domains (7) summary
    smart00045
    Location:521 → 678
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:373 → 494
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG0666
    Location:869 → 1068
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:966 → 997
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:936 → 1031
    Ank_2; Ankyrin repeats (3 copies)
    cd20850
    Location:163 → 235
    C1_DGKiota_rpt1; first protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase iota (DAG kinase iota) and similar proteins
    cd20896
    Location:244 → 318
    C1_DGKiota_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase iota (DAG kinase iota) and similar proteins

  2. NM_001347104.2 → NP_001334033.1  diacylglycerol kinase iota isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC114574, AC154019, AC159480, AC184160
    Consensus CDS
    CCDS85032.1
    UniProtKB/TrEMBL
    D3Z519
    Related
    ENSMUSP00000087788.5, ENSMUST00000090314.11

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    36814316..37281034 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006506259.5 → XP_006506322.1  diacylglycerol kinase iota isoform X8

    UniProtKB/TrEMBL
    D3Z519
    Conserved Domains (6) summary
    smart00045
    Location:516 → 673
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:368 → 489
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG0666
    Location:864 → 1063
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:961 → 992
    ANK; ANK repeat [structural motif]
    pfam00130
    Location:246 → 303
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam12796
    Location:931 → 1026
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_011241385.4 → XP_011239687.1  diacylglycerol kinase iota isoform X16

    UniProtKB/TrEMBL
    D3Z519
    Conserved Domains (6) summary
    smart00045
    Location:520 → 677
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:372 → 493
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG0666
    Location:832 → 1031
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:929 → 960
    ANK; ANK repeat [structural motif]
    pfam00130
    Location:246 → 303
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam12796
    Location:899 → 994
    Ank_2; Ankyrin repeats (3 copies)

  3. XM_006506258.5 → XP_006506321.1  diacylglycerol kinase iota isoform X7

    UniProtKB/TrEMBL
    D3Z519
    Conserved Domains (6) summary
    smart00045
    Location:520 → 677
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:372 → 493
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG0666
    Location:868 → 1067
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:965 → 996
    ANK; ANK repeat [structural motif]
    pfam00130
    Location:246 → 303
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam12796
    Location:935 → 1030
    Ank_2; Ankyrin repeats (3 copies)

  4. XM_030255453.2 → XP_030111313.1  diacylglycerol kinase iota isoform X9

    UniProtKB/TrEMBL
    D3Z519
    Conserved Domains (6) summary
    smart00045
    Location:521 → 678
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:373 → 494
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG0666
    Location:854 → 1053
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:951 → 982
    ANK; ANK repeat [structural motif]
    pfam00130
    Location:246 → 303
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam12796
    Location:921 → 1016
    Ank_2; Ankyrin repeats (3 copies)

  5. XM_017321628.3 → XP_017177117.1  diacylglycerol kinase iota isoform X5

    UniProtKB/TrEMBL
    D3Z519
    Conserved Domains (6) summary
    smart00045
    Location:561 → 718
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:413 → 534
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG0666
    Location:888 → 1087
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:985 → 1016
    ANK; ANK repeat [structural motif]
    pfam00130
    Location:246 → 303
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam12796
    Location:955 → 1050
    Ank_2; Ankyrin repeats (3 copies)

  6. XM_017321625.3 → XP_017177114.1  diacylglycerol kinase iota isoform X2

    Conserved Domains (6) summary
    smart00045
    Location:561 → 718
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:413 → 534
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG0666
    Location:909 → 1108
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:1006 → 1037
    ANK; ANK repeat [structural motif]
    pfam00130
    Location:246 → 303
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam12796
    Location:976 → 1071
    Ank_2; Ankyrin repeats (3 copies)

  7. XM_017321629.3 → XP_017177118.1  diacylglycerol kinase iota isoform X6

    UniProtKB/TrEMBL
    D3Z519
    Conserved Domains (6) summary
    smart00045
    Location:562 → 719
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:414 → 535
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG0666
    Location:874 → 1073
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:971 → 1002
    ANK; ANK repeat [structural motif]
    pfam00130
    Location:246 → 303
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam12796
    Location:941 → 1036
    Ank_2; Ankyrin repeats (3 copies)

  8. XM_017321627.3 → XP_017177116.1  diacylglycerol kinase iota isoform X4

    UniProtKB/TrEMBL
    D3Z519
    Conserved Domains (6) summary
    smart00045
    Location:562 → 719
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:414 → 535
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG0666
    Location:889 → 1088
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:986 → 1017
    ANK; ANK repeat [structural motif]
    pfam00130
    Location:246 → 303
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam12796
    Location:956 → 1051
    Ank_2; Ankyrin repeats (3 copies)

  9. XM_017321626.3 → XP_017177115.1  diacylglycerol kinase iota isoform X3

    Conserved Domains (6) summary
    smart00045
    Location:562 → 719
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:414 → 535
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG0666
    Location:895 → 1094
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:992 → 1023
    ANK; ANK repeat [structural motif]
    pfam00130
    Location:246 → 303
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam12796
    Location:962 → 1057
    Ank_2; Ankyrin repeats (3 copies)

  10. XM_017321624.3 → XP_017177113.1  diacylglycerol kinase iota isoform X1

    Conserved Domains (6) summary
    smart00045
    Location:562 → 719
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:414 → 535
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG0666
    Location:910 → 1109
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:1007 → 1038
    ANK; ANK repeat [structural motif]
    pfam00130
    Location:246 → 303
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam12796
    Location:977 → 1072
    Ank_2; Ankyrin repeats (3 copies)

  11. XM_036166220.1 → XP_036022113.1  diacylglycerol kinase iota isoform X13

    UniProtKB/TrEMBL
    D3Z519
    Conserved Domains (6) summary
    smart00045
    Location:226 → 383
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:78 → 199
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG0666
    Location:574 → 773
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:671 → 702
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:641 → 736
    Ank_2; Ankyrin repeats (3 copies)
    cl00040
    Location:1 → 23
    C1; protein kinase C conserved region 1 (C1 domain) superfamily

  12. XM_036166221.1 → XP_036022114.1  diacylglycerol kinase iota isoform X14

    UniProtKB/TrEMBL
    D3Z519
    Conserved Domains (5) summary
    smart00045
    Location:196 → 353
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:48 → 169
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG0666
    Location:544 → 743
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:641 → 672
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:611 → 706
    Ank_2; Ankyrin repeats (3 copies)

  13. XM_030255454.2 → XP_030111314.1  diacylglycerol kinase iota isoform X12

    UniProtKB/TrEMBL
    S4R2G0
    Conserved Domains (3) summary
    smart00045
    Location:516 → 673
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:368 → 489
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    pfam00130
    Location:246 → 303
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

  14. XM_017321632.3 → XP_017177121.1  diacylglycerol kinase iota isoform X11

    UniProtKB/TrEMBL
    S4R2G0
    Conserved Domains (3) summary
    smart00045
    Location:562 → 719
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:414 → 535
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    pfam00130
    Location:246 → 303
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

  15. XM_017321630.3 → XP_017177119.1  diacylglycerol kinase iota isoform X10

    UniProtKB/TrEMBL
    S4R2G0
    Related
    ENSMUSP00000138628.2, ENSMUST00000138286.8
    Conserved Domains (3) summary
    smart00045
    Location:562 → 719
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:414 → 535
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    pfam00130
    Location:246 → 303
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

  16. XM_017321633.3 → XP_017177122.1  diacylglycerol kinase iota isoform X15

    UniProtKB/TrEMBL
    S4R215
    Related
    ENSMUSP00000138457.2, ENSMUST00000150300.9
    Conserved Domains (3) summary
    smart00046
    Location:414 → 535
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    pfam00130
    Location:246 → 303
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    cl02440
    Location:562 → 624
    DAGK_acc; Diacylglycerol kinase accessory domain

RNA

  1. XR_004942967.1 RNA Sequence

  2. XR_004942966.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
D3YWQ0.1 GenPept UniProtKB/Swiss-Prot:D3YWQ0

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