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Xkr5 X-linked Kx blood group related 5 [ Mus musculus (house mouse) ]

Gene ID: 319581, updated on 4-Jan-2025

Summary

Official Symbol
Xkr5provided by MGI
Official Full Name
X-linked Kx blood group related 5provided by MGI
Primary source
MGI:MGI:2442327
See related
Ensembl:ENSMUSG00000039814 AllianceGenome:MGI:2442327
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
XRG5; 5430438H03Rik
Summary
Is active in plasma membrane. Orthologous to human XKR5 (XK related 5). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See Xkr5 in Genome Data Viewer
Location:
8 A1.3; 8 10.33 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (18974172..19001126, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (18924152..18951105, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr8:18846064-18846365 Neighboring gene STARR-seq mESC enhancer starr_20847 Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase 5 Neighboring gene STARR-seq mESC enhancer starr_20849 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:18899079-18899188 Neighboring gene predicted gene, 35934 Neighboring gene STARR-seq mESC enhancer starr_20852 Neighboring gene STARR-positive B cell enhancer ABC_E4991 Neighboring gene predicted gene, 40464 Neighboring gene defensin beta 40 Neighboring gene defensin beta 37 Neighboring gene predicted gene, 39138

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

Gene Ontology Provided by MGI

Component Evidence Code Pubs
is_active_in membrane  
is_active_in plasma membrane PubMed 

General protein information

Preferred Names
XK-related protein 5
Names
X Kell blood group precursor-related family, member 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001113350.2NP_001106821.1  XK-related protein 5 isoform a

    See identical proteins and their annotated locations for NP_001106821.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (a).
    Source sequence(s)
    AY534251
    Consensus CDS
    CCDS52495.1
    UniProtKB/Swiss-Prot
    Q5GH66
    Related
    ENSMUSP00000093089.4, ENSMUST00000095438.10
    Conserved Domains (1) summary
    pfam09815
    Location:16321
    XK-related; XK-related protein
  2. NM_001286469.1NP_001273398.1  XK-related protein 5 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. This encodes isoform c, which has a shorter and distinct N-terminus, compared to isoform a.
    Source sequence(s)
    AC119161, AK045098, AY534251
    UniProtKB/Swiss-Prot
    Q5GH66
    UniProtKB/TrEMBL
    Q8BG78
    Related
    ENSMUST00000144987.8
    Conserved Domains (1) summary
    pfam09815
    Location:11311
    XK-related; XK-related protein
  3. NM_176951.5NP_795925.1  XK-related protein 5 isoform b

    See identical proteins and their annotated locations for NP_795925.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. This encodes isoform b, which has a shorter N-terminus, compared to isoform a.
    Source sequence(s)
    AK045098, AY534251
    Consensus CDS
    CCDS40245.1
    UniProtKB/TrEMBL
    Q0VFY4, Q8BG78
    Related
    ENSMUSP00000061748.6, ENSMUST00000055503.12
    Conserved Domains (1) summary
    pfam09815
    Location:2155
    XK-related; XK-related protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    18974172..19001126 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006508818.5XP_006508881.1  XK-related protein 5 isoform X3

    Conserved Domains (1) summary
    pfam09815
    Location:16307
    XK-related; XK-related protein
  2. XM_006508817.4XP_006508880.1  XK-related protein 5 isoform X1

    See identical proteins and their annotated locations for XP_006508880.1

    UniProtKB/TrEMBL
    Q0VFY4, Q8BG78
    Conserved Domains (1) summary
    pfam09815
    Location:2155
    XK-related; XK-related protein
  3. XM_011242065.4XP_011240367.1  XK-related protein 5 isoform X2

    Conserved Domains (1) summary
    pfam09815
    Location:16307
    XK-related; XK-related protein
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