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Fcgbpl1 Fc fragment of IgG binding protein like 1 [ Mus musculus (house mouse) ]

Gene ID: 319482, updated on 8-Feb-2024

Summary

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Official Symbol
Fcgbpl1provided by MGI
Official Full Name
Fc fragment of IgG binding protein like 1provided by MGI
Primary source
MGI:MGI:2442118
See related
Ensembl:ENSMUSG00000078776 AllianceGenome:MGI:2442118
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
FCGBP; 9530053A07Rik
Summary
Predicted to be active in extracellular matrix and extracellular space. Orthologous to human FCGBP (Fc fragment of IgG binding protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in colon adult (RPKM 46.8), large intestine adult (RPKM 37.9) and 4 other tissues See more
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Genomic context

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Location:
7 A3; 7 16.54 cM
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (27828891..27864236)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (28129466..28164811)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene Fc fragment of IgG binding protein Neighboring gene tectorin alpha pseudogene Neighboring gene predicted gene, 38976 Neighboring gene predicted gene, 24356 Neighboring gene STARR-seq mESC enhancer starr_18401 Neighboring gene STARR-seq mESC enhancer starr_18402 Neighboring gene STARR-positive B cell enhancer ABC_E6526 Neighboring gene predicted gene, 31024 Neighboring gene fibrillarin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp protein. Johansson ME, et al. J Proteome Res, 2009 Jul. PMID 19432394
  2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Fc fragment of IgG binding protein like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164655.1 → NP_001158127.1  Fc fragment of IgG binding protein like 1 precursor

    Status: PROVISIONAL

    Source sequence(s)
    AC141883, AC158220
    Consensus CDS
    CCDS52160.1
    UniProtKB/TrEMBL
    E9PVG8
    Related
    ENSMUSP00000056479.5, ENSMUST00000059886.12
    Conserved Domains (7) summary
    smart00216
    Location:828 → 988
    VWD; von Willebrand factor (vWF) type D domain
    smart00832
    Location:1033 → 1108
    C8; This domain contains 8 conserved cysteine residues
    pfam00094
    Location:56 → 212
    VWD; von Willebrand factor type D domain
    pfam01826
    Location:1916 → 1969
    TIL; Trypsin Inhibitor like cysteine rich domain
    pfam08742
    Location:644 → 714
    C8; C8 domain
    cl02516
    Location:2404 → 2558
    VWD; von Willebrand factor type D domain
    cl17735
    Location:773 → 827
    VWC; von Willebrand factor type C domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    27828891..27864236
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_176924.4: Suppressed sequence

    Description
    NM_176924.4: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version

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