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Bricd5 BRICHOS domain containing 5 [ Mus musculus (house mouse) ]

Gene ID: 319259, updated on 5-Mar-2024

Summary

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Official Symbol
Bricd5provided by MGI
Official Full Name
BRICHOS domain containing 5provided by MGI
Primary source
MGI:MGI:2441766
See related
Ensembl:ENSMUSG00000045744 AllianceGenome:MGI:2441766
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9930021D14Rik
Summary
Predicted to be involved in regulation of cell population proliferation. Predicted to be active in extracellular space. Orthologous to human BRICD5 (BRICHOS domain containing 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thymus adult (RPKM 14.1), ovary adult (RPKM 13.9) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Bricd5 in Genome Data Viewer
Location:
17 A3.3; 17 12.39 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (24692858..24694443)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (24473487..24475471)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4833447I15 gene Neighboring gene STARR-positive B cell enhancer ABC_E7497 Neighboring gene STARR-positive B cell enhancer ABC_E5578 Neighboring gene phosphoglycolate phosphatase Neighboring gene MTOR associated protein, LST8 homolog (S. cerevisiae) Neighboring gene STARR-seq mESC enhancer starr_42087 Neighboring gene CASK interacting protein 1 Neighboring gene TNF receptor-associated factor 7 Neighboring gene STARR-positive B cell enhancer ABC_E33 Neighboring gene RAB26, member RAS oncogene family, opposite strand Neighboring gene small nucleolar RNA, C/D box 60

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. An SFTPC BRICHOS mutant links epithelial ER stress and spontaneous lung fibrosis. Katzen J, et al. JCI Insight, 2019 Mar 21. PMID 30721158, Free PMC Article
  2. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. An SFTPC BRICHOS mutant links epithelial ER stress and spontaneous lung fibrosis.
    Title: An SFTPC BRICHOS mutant links epithelial ER stress and spontaneous lung fibrosis.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in regulation of cell population proliferation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
BRICHOS domain-containing protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175682.3 → NP_783613.1  BRICHOS domain-containing protein 5

    See identical proteins and their annotated locations for NP_783613.1

    Status: PROVISIONAL

    Source sequence(s)
    AK079437
    Consensus CDS
    CCDS28483.1
    UniProtKB/TrEMBL
    F6RA38, Q4VAG0, Q8BV89
    Related
    ENSMUSP00000059792.4, ENSMUST00000054946.10
    Conserved Domains (1) summary
    smart01039
    Location:44 → 138
    BRICHOS; The BRICHOS domain is found in a variety of proteins implicated in dementia, respiratory distress and cancer

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    24692858..24694443
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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