VN1R5 vomeronasal 1 receptor 5 (gene/pseudogene) [Homo sapiens (human)] - Gene

Summary

Official Symbol: VN1R5provided by HGNC
Official Full Name: vomeronasal 1 receptor 5 (gene/pseudogene)provided by HGNC
Primary source: HGNC:HGNC:19870
See related: Ensembl:ENSG00000197617 AllianceGenome:HGNC:19870
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: V1RL5
Summary: Predicted to enable pheromone receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and response to pheromone. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Annotation information: Annotation category: suggests misassembly; Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene.
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 1q44

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	GRCh38.p14 (GCF_000001405.40)	1	NC_000001.11 (247256072..247257145)
RS_2023_10	current	T2T-CHM13v2.0 (GCF_009914755.1)	1	NC_060925.1 (246689208..246690281)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	1	NC_000001.10 (247419374..247420447)

Chromosome 1 - NC_000001.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Phenotypes

Go to the top of the page Help

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

NoName (e-PCR)
- UniSTS:494906

NoName (e-PCR)
- UniSTS:484163

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables pheromone receptor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in response to pheromone	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: vomeronasal type-1 receptor 5

Names: G-protein coupled receptor GPCR26; V1R-like 5; V1r-like receptor 5; hGPCR26; pheromone receptor

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_173858.1 → NP_776257.1 vomeronasal type-1 receptor 5

See identical proteins and their annotated locations for NP_776257.1

Status: VALIDATED

Source sequence(s)

AY114735

UniProtKB/Swiss-Prot

A0AVG1, Q7Z5H4, Q8NEU5, Q8TDU3

Conserved Domains (1) summary

cd13949
Location:43 → 336

7tm_V1R_pheromone; vomeronasal organ pheromone receptor type-1 family, member of the seven-transmembrane G protein-coupled receptor superfamily

RNA

NR_160309.1 RNA Sequence

Status: VALIDATED

Description

Transcript Variant: This variant (1, non-coding) contains a polymorphic nt that creates an early termination codon compared to variant 1, coding. The resulting transcript is considered to be non-protein coding since it is a candidate for nonsense-mediated mRNA decay (NMD).

Source sequence(s)

AC104335

Related

ENST00000472952.3