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Ubn2 ubinuclein 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 312248, updated on 11-Apr-2024

Summary

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Official Symbol
Ubn2provided by RGD
Official Full Name
ubinuclein 2provided by RGD
Primary source
RGD:1310722
See related
Ensembl:ENSRNOG00000005564 AllianceGenome:RGD:1310722
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1310722
Summary
Predicted to be involved in DNA replication-independent chromatin assembly. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Orthologous to human UBN2 (ubinuclein 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Adrenal (RPKM 90.8), Thymus (RPKM 78.7) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ubn2 in Genome Data Viewer
Location:
4q23
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (68130497..68218471)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (67165278..67251562)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (66164639..66254297)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene high-mobility group box 1, pseudogene 18 Neighboring gene zinc finger CCCH-type containing, antiviral 1 Neighboring gene high mobility group protein B1 pseudogene Neighboring gene intraflagellar transport 56 Neighboring gene large ribosomal subunit protein uL14-like Neighboring gene uncharacterized LOC134486759

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy. Pieragostino D, et al. Mol Biosyst, 2013 Jun. PMID 23580065
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in chromatin organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ubinuclein-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134553.1 → NP_001128025.1  ubinuclein-2

    See identical proteins and their annotated locations for NP_001128025.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473959
    UniProtKB/Swiss-Prot
    D4A666
    UniProtKB/TrEMBL
    A0A8I6A379
    Related
    ENSRNOP00000085092.1, ENSRNOT00000096491.1
    Conserved Domains (3) summary
    pfam05722
    Location:1017 → 1132
    Ustilago_mating; Ustilago B locus mating-type protein
    pfam08729
    Location:182 → 231
    HUN; HPC2 and ubinuclein domain
    pfam14075
    Location:442 → 648
    UBN_AB; Ubinuclein conserved middle domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    68130497..68218471
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006236311.5 → XP_006236373.1  ubinuclein-2 isoform X5

    UniProtKB/TrEMBL
    A0A8I6A379
    Conserved Domains (3) summary
    pfam05722
    Location:1019 → 1134
    Ustilago_mating; Ustilago B locus mating-type protein
    pfam08729
    Location:182 → 231
    HUN; HPC2 and ubinuclein domain
    pfam14075
    Location:442 → 650
    UBN_AB; Ubinuclein conserved middle domain

  2. XM_063285997.1 → XP_063142067.1  ubinuclein-2 isoform X4

  3. XM_006236306.5 → XP_006236368.1  ubinuclein-2 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A379, A0A8L2UN89
    Related
    ENSRNOP00000061860.2
    Conserved Domains (3) summary
    pfam05722
    Location:1019 → 1134
    Ustilago_mating; Ustilago B locus mating-type protein
    pfam08729
    Location:182 → 231
    HUN; HPC2 and ubinuclein domain
    pfam14075
    Location:442 → 650
    UBN_AB; Ubinuclein conserved middle domain

  4. XM_006236307.5 → XP_006236369.1  ubinuclein-2 isoform X2

    UniProtKB/TrEMBL
    A0A8I6A0V7, A0A8I6A379
    Related
    ENSRNOP00000083893.1
    Conserved Domains (3) summary
    pfam05722
    Location:1002 → 1117
    Ustilago_mating; Ustilago B locus mating-type protein
    pfam08729
    Location:182 → 231
    HUN; HPC2 and ubinuclein domain
    pfam14075
    Location:442 → 650
    UBN_AB; Ubinuclein conserved middle domain

  5. XM_006236308.5 → XP_006236370.1  ubinuclein-2 isoform X3

    UniProtKB/TrEMBL
    A0A8I6A379
    Conserved Domains (3) summary
    pfam05722
    Location:1000 → 1115
    Ustilago_mating; Ustilago B locus mating-type protein
    pfam08729
    Location:182 → 231
    HUN; HPC2 and ubinuclein domain
    pfam14075
    Location:442 → 648
    UBN_AB; Ubinuclein conserved middle domain

  6. XM_063285998.1 → XP_063142068.1  ubinuclein-2 isoform X6

  7. XM_063285999.1 → XP_063142069.1  ubinuclein-2 isoform X7

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
D4A666.1 GenPept UniProtKB/Swiss-Prot:D4A666

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