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Zfp212 Zinc finger protein 212 [ Rattus norvegicus (Norway rat) ]

Gene ID: 297066, updated on 11-Apr-2024

Summary

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Official Symbol
Zfp212provided by RGD
Official Full Name
Zinc finger protein 212provided by RGD
Primary source
RGD:1307836
See related
Ensembl:ENSRNOG00000006711 AllianceGenome:RGD:1307836
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Orthologous to human ZNF212 (zinc finger protein 212). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 120.9), Lung (RPKM 84.1) and 9 other tissues See more
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Genomic context

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Location:
4q24
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (78254582..78267017)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (76923638..76936076)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (77591880..77604307)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 398 Neighboring gene zinc finger protein 282 Neighboring gene ATP synthase subunit delta, mitochondrial pseudogene Neighboring gene zinc finger protein 956 Neighboring gene zinc finger protein 783 Neighboring gene transfer RNA cysteine (anticodon GCA) 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. A protein-protein interaction network of transcription factors acting during liver cell proliferation. Gao J, et al. Genomics, 2008 Apr. PMID 18255255
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
  
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
acts_upstream_of_or_within dendrite development ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within general adaptation syndrome, behavioral process ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within neuromuscular process controlling balance ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within neuron apoptotic process ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within response to alcohol ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within walking behavior ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger protein 212

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001100839.1 → NP_001094309.1  zinc finger protein 212

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000004
    UniProtKB/TrEMBL
    A6K0D6
    Conserved Domains (4) summary
    cd07765
    Location:142 → 180
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    COG5048
    Location:329 → 474
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:368 → 388
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:426 → 446
    zf-C2H2; Zinc finger, C2H2 type

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    78254582..78267017
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006236446.5 → XP_006236508.1  zinc finger protein 212 isoform X1

    See identical proteins and their annotated locations for XP_006236508.1

    UniProtKB/TrEMBL
    G3V6U6
    Related
    ENSRNOP00000009054.6
    Conserved Domains (5) summary
    cd07765
    Location:142 → 180
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    COG5048
    Location:318 → 473
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:367 → 387
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:425 → 445
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:437 → 462
    zf-H2C2_2; Zinc-finger double domain

  2. XM_039108653.2 → XP_038964581.1  zinc finger protein 212 isoform X2

    UniProtKB/TrEMBL
    Q52KK5
    Conserved Domains (4) summary
    cd07765
    Location:88 → 126
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    COG5048
    Location:275 → 420
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:314 → 334
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:372 → 392
    zf-C2H2; Zinc finger, C2H2 type
Nucleotide Protein Strain
Heading Accession and Version

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