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FAM156A family with sequence similarity 156 member A [ Homo sapiens (human) ]

Gene ID: 29057, updated on 3-Apr-2024

Summary

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Official Symbol
FAM156Aprovided by HGNC
Official Full Name
family with sequence similarity 156 member Aprovided by HGNC
Primary source
HGNC:HGNC:30114
See related
Ensembl:ENSG00000268350 AllianceGenome:HGNC:30114
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TMEM29; PRO0659
Summary
Predicted to enable methylated histone binding activity. Located in nuclear envelope. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in skin (RPKM 15.8), placenta (RPKM 14.5) and 25 other tissues See more
Orthologs
all
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Genomic context

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Location:
Xp11.22
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (52947254..52995472, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (52231792..52279984, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (52976462..53024651, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 156 member B Neighboring gene H3K27ac hESC enhancer GRCh37_chrX:52949629-52950232 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29646 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29647 Neighboring gene uncharacterized LOC124905190 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29648 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29649 Neighboring gene H3K27ac hESC enhancer GRCh37_chrX:52963212-52964184 Neighboring gene H3K27ac hESC enhancer GRCh37_chrX:52964185-52965156 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:53018839-53019418 Neighboring gene ReSE screen-validated silencer GRCh37_chrX:53045322-53045423 Neighboring gene G protein-coupled receptor 173 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:53100667-53101168 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29651 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20852 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20853 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20854 Neighboring gene TSPY like 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. The DNA sequence of the human X chromosome. Ross MT, et al. Nature, 2005 Mar 17. PMID 15772651, Free PMC Article
  2. Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. Wang AG, et al. Biochem Biophys Res Commun, 2006 Jul 7. PMID 16712791
  3. Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. Simpson JC, et al. EMBO Rep, 2000 Sep. PMID 11256614, Free PMC Article
  4. The LIFEdb database in 2006. Mehrle A, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381901, Free PMC Article
  5. From ORFeome to biology: a functional genomics pipeline. Wiemann S, et al. Genome Res, 2004 Oct. PMID 15489336, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • DKFZp686B22211

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables methylated histone binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in nuclear envelope IDA
Inferred from Direct Assay
more info
  

General protein information

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Preferred Names
protein FAM156A/FAM156B
Names
protein FAM156A
transmembrane protein 29
transmembrane protein 29/29B

NCBI Reference Sequences (RefSeq)

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NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001242489.2 → NP_001229418.1  protein FAM156A/FAM156B

    See identical proteins and their annotated locations for NP_001229418.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-10 encode the same protein.
    Source sequence(s)
    AK057692, BC000867, DA685609, DA849151
    Consensus CDS
    CCDS35297.1
    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    UniProtKB/TrEMBL
    A0A087WVC8
    Related
    ENSP00000479184.1, ENST00000615092.4
    Conserved Domains (1) summary
    pfam15549
    Location:1 → 170
    PGC7_Stella; PGC7/Stella/Dppa3 domain

  2. NM_001242490.2 → NP_001229419.1  protein FAM156A/FAM156B

    See identical proteins and their annotated locations for NP_001229419.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-10 encode the same protein.
    Source sequence(s)
    BC000867, BU192418, DA347198, DA572135
    Consensus CDS
    CCDS35297.1
    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    UniProtKB/TrEMBL
    A0A087WVC8
    Related
    ENSP00000477905.2, ENST00000622323.5
    Conserved Domains (1) summary
    pfam15549
    Location:1 → 170
    PGC7_Stella; PGC7/Stella/Dppa3 domain

  3. NM_001242491.1 → NP_001229420.1  protein FAM156A/FAM156B

    See identical proteins and their annotated locations for NP_001229420.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1-10 encode the same protein.
    Source sequence(s)
    AK057692, BC000867, DA371625
    Consensus CDS
    CCDS35297.1
    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    UniProtKB/TrEMBL
    A0A087WVC8
    Related
    ENSP00000481435.1, ENST00000617970.4
    Conserved Domains (1) summary
    pfam15549
    Location:1 → 170
    PGC7_Stella; PGC7/Stella/Dppa3 domain

  4. NM_001242492.2 → NP_001229421.1  protein FAM156A/FAM156B

    See identical proteins and their annotated locations for NP_001229421.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1-10 encode the same protein.
    Source sequence(s)
    BC000867, BC067819, BI829697, DA685609
    Consensus CDS
    CCDS35297.1
    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    UniProtKB/TrEMBL
    A0A087WVC8
    Related
    ENSP00000485247.1, ENST00000623782.3
    Conserved Domains (1) summary
    pfam15549
    Location:1 → 170
    PGC7_Stella; PGC7/Stella/Dppa3 domain

  5. NM_001242493.2 → NP_001229422.1  protein FAM156A/FAM156B

    See identical proteins and their annotated locations for NP_001229422.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. Variants 1-10 encode the same protein.
    Source sequence(s)
    BC000867, DA347198, DA572135, DA691898
    Consensus CDS
    CCDS35297.1
    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    UniProtKB/TrEMBL
    A0A087WVC8
    Related
    ENSP00000484967.2, ENST00000612083.5
    Conserved Domains (1) summary
    pfam15549
    Location:1 → 170
    PGC7_Stella; PGC7/Stella/Dppa3 domain

  6. NM_001242494.2 → NP_001229423.1  protein FAM156A/FAM156B

    See identical proteins and their annotated locations for NP_001229423.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 1. Variants 1-10 encode the same protein.
    Source sequence(s)
    BC000867, DA347198, DA685609
    Consensus CDS
    CCDS35297.1
    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    UniProtKB/TrEMBL
    A0A087WVC8
    Conserved Domains (1) summary
    pfam15549
    Location:1 → 170
    PGC7_Stella; PGC7/Stella/Dppa3 domain

  7. NM_001242495.2 → NP_001229424.1  protein FAM156A/FAM156B

    See identical proteins and their annotated locations for NP_001229424.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR compared to variant 1. Variants 1-10 encode the same protein.
    Source sequence(s)
    BC000867, BC067819, DA685609
    Consensus CDS
    CCDS35297.1
    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    UniProtKB/TrEMBL
    A0A087WVC8
    Related
    ENSP00000480518.1, ENST00000611661.4
    Conserved Domains (1) summary
    pfam15549
    Location:1 → 170
    PGC7_Stella; PGC7/Stella/Dppa3 domain

  8. NM_001242496.2 → NP_001229425.1  protein FAM156A/FAM156B

    See identical proteins and their annotated locations for NP_001229425.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9) differs in the 5' UTR compared to variant 1. Variants 1-10 encode the same protein.
    Source sequence(s)
    BC000867, BC067819, CB139342, DA572135
    Consensus CDS
    CCDS35297.1
    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    UniProtKB/TrEMBL
    A0A087WVC8
    Related
    ENSP00000484757.2, ENST00000619373.5
    Conserved Domains (1) summary
    pfam15549
    Location:1 → 170
    PGC7_Stella; PGC7/Stella/Dppa3 domain

  9. NM_001242497.2 → NP_001229426.1  protein FAM156A/FAM156B

    See identical proteins and their annotated locations for NP_001229426.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (10) differs in the 5' UTR compared to variant 1. Variants 1-10 encode the same protein.
    Source sequence(s)
    AF090943, DA368012, DA572135
    Consensus CDS
    CCDS35297.1
    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    UniProtKB/TrEMBL
    A0A087WVC8
    Related
    ENSP00000479338.2, ENST00000622732.5
    Conserved Domains (1) summary
    pfam15549
    Location:1 → 170
    PGC7_Stella; PGC7/Stella/Dppa3 domain

  10. NM_001377060.1 → NP_001363989.1  protein FAM156A/FAM156B

    Status: VALIDATED

    Source sequence(s)
    AC234031
    Consensus CDS
    CCDS35297.1
    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    UniProtKB/TrEMBL
    A0A087WVC8
    Related
    ENSP00000471676.1, ENST00000596733.7
    Conserved Domains (1) summary
    pfam15549
    Location:1 → 170
    PGC7_Stella; PGC7/Stella/Dppa3 domain

  11. NM_001377061.1 → NP_001363990.1  protein FAM156A/FAM156B

    Status: VALIDATED

    Source sequence(s)
    AC234031
    Consensus CDS
    CCDS35297.1
    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    UniProtKB/TrEMBL
    A0A087WVC8
    Related
    ENSP00000482562.2, ENST00000619518.5
    Conserved Domains (1) summary
    pfam15549
    Location:1 → 170
    PGC7_Stella; PGC7/Stella/Dppa3 domain

  12. NM_001377062.1 → NP_001363991.1  protein FAM156A/FAM156B

    Status: VALIDATED

    Source sequence(s)
    AC234031
    Consensus CDS
    CCDS35297.1
    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    UniProtKB/TrEMBL
    A0A087WVC8
    Conserved Domains (1) summary
    pfam15549
    Location:1 → 170
    PGC7_Stella; PGC7/Stella/Dppa3 domain

  13. NM_001377063.1 → NP_001363992.1  protein FAM156A/FAM156B

    Status: VALIDATED

    Source sequence(s)
    AC234031
    Consensus CDS
    CCDS35297.1
    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    UniProtKB/TrEMBL
    A0A087WVC8
    Related
    ENSP00000480373.1, ENST00000613284.1
    Conserved Domains (1) summary
    pfam15549
    Location:1 → 170
    PGC7_Stella; PGC7/Stella/Dppa3 domain

  14. NM_001387706.1 → NP_001374635.1  protein FAM156A/FAM156B

    Status: VALIDATED

    Source sequence(s)
    AC234031
    Consensus CDS
    CCDS35297.1
    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    UniProtKB/TrEMBL
    A0A087WVC8
    Related
    ENSP00000482142.1, ENST00000622447.5
    Conserved Domains (1) summary
    pfam15549
    Location:1 → 170
    PGC7_Stella; PGC7/Stella/Dppa3 domain

  15. NM_014138.5 → NP_054857.2  protein FAM156A/FAM156B

    See identical proteins and their annotated locations for NP_054857.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1-10 encode the same protein.
    Source sequence(s)
    AK057692, BC000867, DA256347, DA572135
    Consensus CDS
    CCDS35297.1
    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    UniProtKB/TrEMBL
    A0A087WVC8
    Related
    ENSP00000484167.1, ENST00000612915.4
    Conserved Domains (1) summary
    pfam15549
    Location:1 → 170
    PGC7_Stella; PGC7/Stella/Dppa3 domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    52947254..52995472 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017029457.1 → XP_016884946.1  protein FAM156A/FAM156B isoform X1

    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    UniProtKB/TrEMBL
    A0A087WVC8
    Conserved Domains (1) summary
    pfam15549
    Location:1 → 170
    PGC7_Stella; PGC7/Stella/Dppa3 domain

  2. XM_047442036.1 → XP_047297992.1  protein FAM156A/FAM156B isoform X1

    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49

  3. XM_047442034.1 → XP_047297990.1  protein FAM156A/FAM156B isoform X1

    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    Related
    ENSP00000482980.2, ENST00000618601.5

  4. XM_047442033.1 → XP_047297989.1  protein FAM156A/FAM156B isoform X1

    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    Related
    ENSP00000479348.2, ENST00000612846.5

  5. XM_047442037.1 → XP_047297993.1  protein FAM156A/FAM156B isoform X1

    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49

  6. XM_047442032.1 → XP_047297988.1  protein FAM156A/FAM156B isoform X1

    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
    Related
    ENSP00000479822.2, ENST00000619586.5

  7. XM_047442035.1 → XP_047297991.1  protein FAM156A/FAM156B isoform X1

    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    52231792..52279984 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054326919.1 → XP_054182894.1  protein FAM156A/FAM156B isoform X1

    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49

  2. XM_054326916.1 → XP_054182891.1  protein FAM156A/FAM156B isoform X1

    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49

  3. XM_054326917.1 → XP_054182892.1  protein FAM156A/FAM156B isoform X1

    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49

  4. XM_054326915.1 → XP_054182890.1  protein FAM156A/FAM156B isoform X1

    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49

  5. XM_054326920.1 → XP_054182895.1  protein FAM156A/FAM156B isoform X1

    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49

  6. XM_054326914.1 → XP_054182889.1  protein FAM156A/FAM156B isoform X1

    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49

  7. XM_054326918.1 → XP_054182893.1  protein FAM156A/FAM156B isoform X1

    UniProtKB/Swiss-Prot
    B3KQ92, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8NDB6.1 GenPept UniProtKB/Swiss-Prot:Q8NDB6

Gene LinkOut

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