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Tmed5 transmembrane p24 trafficking protein 5 [ Rattus norvegicus (Norway rat) ]

Gene ID: 289883, updated on 11-Apr-2024

Summary

Official Symbol
Tmed5provided by RGD
Official Full Name
transmembrane p24 trafficking protein 5provided by RGD
Primary source
RGD:1359437
See related
Ensembl:ENSRNOG00000000073 AllianceGenome:RGD:1359437
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
LRRG00120
Summary
Predicted to be involved in Golgi ribbon formation; endoplasmic reticulum to Golgi vesicle-mediated transport; and intracellular protein transport. Predicted to be located in cis-Golgi network and endoplasmic reticulum exit site. Predicted to be active in several cellular components, including COPII-coated ER to Golgi transport vesicle; Golgi apparatus; and endoplasmic reticulum-Golgi intermediate compartment. Orthologous to human TMED5 (transmembrane p24 trafficking protein 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Liver (RPKM 320.1), Thymus (RPKM 173.3) and 9 other tissues See more
Orthologs
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Genomic context

Location:
14p22
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (1752857..1763990)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (1607895..1619028)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (2613318..2624773)

Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene down-regulator of transcription 1 Neighboring gene coiled-coil domain containing 18 Neighboring gene adaptor related protein complex 2 subunit sigma 1, pseudogene 1 Neighboring gene metal response element binding transcription factor 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Clone Names

  • MGC95001

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables cargo receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in Golgi ribbon formation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in Golgi ribbon formation IEA
Inferred from Electronic Annotation
more info
 
involved_in Golgi ribbon formation ISO
Inferred from Sequence Orthology
more info
 
involved_in Golgi ribbon formation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in COPII-coated ER to Golgi transport vesicle IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cis-Golgi network IEA
Inferred from Electronic Annotation
more info
 
located_in cis-Golgi network ISO
Inferred from Sequence Orthology
more info
 
located_in cis-Golgi network ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum exit site IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum exit site ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum exit site ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum-Golgi intermediate compartment ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum-Golgi intermediate compartment ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in endoplasmic reticulum-Golgi intermediate compartment membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transmembrane emp24 domain-containing protein 5
Names
p24 family protein gamma-2
p24gamma2
transmembrane emp24 protein transport domain containing 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007619.1NP_001007620.1  transmembrane emp24 domain-containing protein 5 precursor

    See identical proteins and their annotated locations for NP_001007620.1

    Status: PROVISIONAL

    Source sequence(s)
    BC079452
    UniProtKB/Swiss-Prot
    Q6AXN3
    UniProtKB/TrEMBL
    A6KPG8
    Related
    ENSRNOP00000084338.1, ENSRNOT00000119350.1
    Conserved Domains (1) summary
    pfam01105
    Location:35222
    EMP24_GP25L; emp24/gp25L/p24 family/GOLD

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086032.1 Reference GRCr8

    Range
    1752857..1763990
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)