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OR4C12 olfactory receptor family 4 subfamily C member 12 [ Homo sapiens (human) ]

Gene ID: 283093, updated on 10-Dec-2024

Summary

Official Symbol
OR4C12provided by HGNC
Official Full Name
olfactory receptor family 4 subfamily C member 12provided by HGNC
Primary source
HGNC:HGNC:15168
See related
Ensembl:ENSG00000221954 AllianceGenome:HGNC:15168
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR11-259
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR4C12 in Genome Data Viewer
Location:
11p11.12
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (49981473..49982535, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (50158767..50159829, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (50003009..50004071, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 4 subfamily R member 3 pseudogene Neighboring gene olfactory receptor family 4 subfamily C member 13 Neighboring gene olfactory receptor family 4 subfamily C member 48 pseudogene Neighboring gene olfactory receptor family 4 subfamily C member 45 (gene/pseudogene)

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity  
enables olfactory receptor activity  
Component Evidence Code Pubs
is_active_in plasma membrane  
located_in plasma membrane  

General protein information

Preferred Names
olfactory receptor 4C12
Names
olfactory receptor OR11-259
seven transmembrane helix receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_053127.1 RefSeqGene

    Range
    5001..6063
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001005270.4NP_001005270.3  olfactory receptor 4C12

    See identical proteins and their annotated locations for NP_001005270.3

    Status: REVIEWED

    Source sequence(s)
    AC110057
    Consensus CDS
    CCDS31496.1
    UniProtKB/Swiss-Prot
    B2RNF0, Q6IF49, Q96R67
    UniProtKB/TrEMBL
    A0A126GVI4
    Related
    ENSP00000334418.4, ENST00000335238.4
    Conserved Domains (2) summary
    pfam00001
    Location:39285
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:29303
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    49981473..49982535 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_017363816.1 Reference GRCh38.p14 PATCHES

    Range
    23101..24163 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    50158767..50159829 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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