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Zfp385c zinc finger protein 385C [ Mus musculus (house mouse) ]

Gene ID: 278304, updated on 11-Apr-2024

Summary

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Official Symbol
Zfp385cprovided by MGI
Official Full Name
zinc finger protein 385Cprovided by MGI
Primary source
MGI:MGI:3608347
See related
Ensembl:ENSMUSG00000014198 AllianceGenome:MGI:3608347
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Znf385c; A930006D11Rik
Summary
Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to be active in nucleus. Orthologous to human ZNF385C (zinc finger protein 385C). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 25.5), large intestine adult (RPKM 12.2) and 27 other tissues See more
Orthologs
human all
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Genomic context

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Location:
11 D; 11 63.47 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (100517045..100583292, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (100626219..100692466, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:100443371-100443554 Neighboring gene 2',3'-cyclic nucleotide 3' phosphodiesterase Neighboring gene DnaJ heat shock protein family (Hsp40) member C7 Neighboring gene STARR-positive B cell enhancer ABC_E4000 Neighboring gene STARR-positive B cell enhancer ABC_E7061 Neighboring gene STARR-positive B cell enhancer ABC_E2369 Neighboring gene STARR-positive B cell enhancer ABC_E7062 Neighboring gene NFKB inhibitor interacting Ras-like protein 2 Neighboring gene chromosome 11 C17orf113 homolog Neighboring gene predicted gene, 38483 Neighboring gene STARR-positive B cell enhancer ABC_E7063 Neighboring gene STARR-positive B cell enhancer ABC_E9843 Neighboring gene DExH-box helicase 58 Neighboring gene K(lysine) acetyltransferase 2A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 385C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001373887.1 → NP_001360816.1  zinc finger protein 385C isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL591469
    Conserved Domains (4) summary
    smart00451
    Location:45 → 74
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:311 → 379
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam04988
    Location:378 → 445
    AKAP95; A-kinase anchoring protein 95 (AKAP95)
    pfam12874
    Location:379 → 402
    zf-met; Zinc-finger of C2H2 type

  2. NM_001373888.1 → NP_001360817.1  zinc finger protein 385C isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL591469
    Conserved Domains (4) summary
    smart00451
    Location:45 → 74
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:310 → 378
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam04988
    Location:377 → 444
    AKAP95; A-kinase anchoring protein 95 (AKAP95)
    pfam12874
    Location:378 → 401
    zf-met; Zinc-finger of C2H2 type

  3. NM_001373889.1 → NP_001360818.1  zinc finger protein 385C isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL591469
    Conserved Domains (3) summary
    smart00451
    Location:45 → 74
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:311 → 379
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12874
    Location:379 → 402
    zf-met; Zinc-finger of C2H2 type

  4. NM_001373890.1 → NP_001360819.1  zinc finger protein 385C isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL591469
    Conserved Domains (3) summary
    sd00020
    Location:231 → 299
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam04988
    Location:298 → 365
    AKAP95; A-kinase anchoring protein 95 (AKAP95)
    pfam12874
    Location:299 → 322
    zf-met; Zinc-finger of C2H2 type

  5. NM_177790.4 → NP_808458.2  zinc finger protein 385C isoform 5

    See identical proteins and their annotated locations for NP_808458.2

    Status: VALIDATED

    Source sequence(s)
    AL591469
    Consensus CDS
    CCDS25430.1
    UniProtKB/Swiss-Prot
    A2A5E6, Q14AS5, Q8C8X1
    Related
    ENSMUSP00000099408.4, ENSMUST00000103119.10
    Conserved Domains (3) summary
    sd00020
    Location:230 → 298
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam04988
    Location:297 → 364
    AKAP95; A-kinase anchoring protein 95 (AKAP95)
    pfam12874
    Location:298 → 321
    zf-met; Zinc-finger of C2H2 type

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    100517045..100583292 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030246059.1 → XP_030101919.1  zinc finger protein 385C isoform X3

    Conserved Domains (4) summary
    smart00451
    Location:103 → 132
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:369 → 437
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam04988
    Location:436 → 503
    AKAP95; A-kinase anchoring protein 95 (AKAP95)
    pfam12874
    Location:437 → 460
    zf-met; Zinc-finger of C2H2 type

  2. XM_030246056.1 → XP_030101916.1  zinc finger protein 385C isoform X2

    Conserved Domains (4) summary
    smart00451
    Location:132 → 161
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:397 → 465
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam04988
    Location:464 → 531
    AKAP95; A-kinase anchoring protein 95 (AKAP95)
    pfam12874
    Location:465 → 488
    zf-met; Zinc-finger of C2H2 type

  3. XM_006533488.4 → XP_006533551.3  zinc finger protein 385C isoform X1

    Conserved Domains (4) summary
    smart00451
    Location:132 → 161
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:398 → 466
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam04988
    Location:465 → 532
    AKAP95; A-kinase anchoring protein 95 (AKAP95)
    pfam12874
    Location:466 → 489
    zf-met; Zinc-finger of C2H2 type

  4. XM_006533492.5 → XP_006533555.1  zinc finger protein 385C isoform X4

    See identical proteins and their annotated locations for XP_006533555.1

    Conserved Domains (4) summary
    smart00451
    Location:45 → 74
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:311 → 379
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam04988
    Location:378 → 445
    AKAP95; A-kinase anchoring protein 95 (AKAP95)
    pfam12874
    Location:379 → 402
    zf-met; Zinc-finger of C2H2 type

  5. XM_011249062.3 → XP_011247364.1  zinc finger protein 385C isoform X5

    Conserved Domains (3) summary
    sd00020
    Location:230 → 298
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam04988
    Location:297 → 364
    AKAP95; A-kinase anchoring protein 95 (AKAP95)
    pfam12874
    Location:298 → 321
    zf-met; Zinc-finger of C2H2 type

  6. XM_006533496.4 → XP_006533559.1  zinc finger protein 385C isoform X6

    Conserved Domains (3) summary
    sd00020
    Location:178 → 246
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam04988
    Location:245 → 312
    AKAP95; A-kinase anchoring protein 95 (AKAP95)
    pfam12874
    Location:246 → 269
    zf-met; Zinc-finger of C2H2 type
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A2A5E6.1 GenPept UniProtKB/Swiss-Prot:A2A5E6

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