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Lkaaear1 LKAAEAR motif containing 1 (IKAAEAR murine motif) [ Mus musculus (house mouse) ]

Gene ID: 277496, updated on 5-Mar-2024

Summary

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Official Symbol
Lkaaear1provided by MGI
Official Full Name
LKAAEAR motif containing 1 (IKAAEAR murine motif)provided by MGI
Primary source
MGI:MGI:2685538
See related
Ensembl:ENSMUSG00000045794 AllianceGenome:MGI:2685538
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm692; 4930526D03Rik
Summary
Orthologous to human LKAAEAR1 (LKAAEAR motif containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 83.1) See more
Orthologs
human all
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Genomic context

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Location:
2 H4; 2 103.73 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (181338586..181340235, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (181696793..181698442, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene transcription elongation factor A (SII), 2 Neighboring gene regulator of G-protein signaling 19 Neighboring gene STARR-positive B cell enhancer mm9_chr2:181441345-181441645 Neighboring gene opioid receptor-like 1 Neighboring gene neuropeptides B/W receptor 2 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
  2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
  5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
protein LKAAEAR1
Names
LKAAEAR motif-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001378943.1 → NP_001365872.1  protein LKAAEAR1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL845173
    Conserved Domains (1) summary
    pfam15478
    Location:44 → 179
    LKAAEAR; Family of unknown function with LKAAEAR motif

  2. NM_199023.3 → NP_950188.2  protein LKAAEAR1 isoform 2

    See identical proteins and their annotated locations for NP_950188.2

    Status: VALIDATED

    Source sequence(s)
    AK076877, BC087873
    Consensus CDS
    CCDS17221.1
    UniProtKB/Swiss-Prot
    Q5I0W3, Q8BIG2
    Related
    ENSMUSP00000061134.4, ENSMUST00000052416.4
    Conserved Domains (1) summary
    pfam15478
    Location:44 → 179
    LKAAEAR; Family of unknown function with LKAAEAR motif

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    181338586..181340235 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030251720.1 → XP_030107580.1  protein LKAAEAR1 isoform X4

    Conserved Domains (1) summary
    pfam15478
    Location:44 → 179
    LKAAEAR; Family of unknown function with LKAAEAR motif

  2. XM_030251704.1 → XP_030107564.1  protein LKAAEAR1 isoform X1

    Conserved Domains (1) summary
    pfam15478
    Location:62 → 197
    LKAAEAR; Family of unknown function with LKAAEAR motif

  3. XM_006500655.3 → XP_006500718.1  protein LKAAEAR1 isoform X6

    Conserved Domains (1) summary
    pfam15478
    Location:62 → 197
    LKAAEAR; Family of unknown function with LKAAEAR motif

  4. XM_006500654.1 → XP_006500717.1  protein LKAAEAR1 isoform X5

    Conserved Domains (1) summary
    pfam15478
    Location:62 → 197
    LKAAEAR; Family of unknown function with LKAAEAR motif

  5. XM_030251721.1 → XP_030107581.1  protein LKAAEAR1 isoform X4

    Conserved Domains (1) summary
    pfam15478
    Location:44 → 179
    LKAAEAR; Family of unknown function with LKAAEAR motif

  6. XM_030251707.1 → XP_030107567.1  protein LKAAEAR1 isoform X3

    Conserved Domains (1) summary
    pfam15478
    Location:55 → 190
    LKAAEAR; Family of unknown function with LKAAEAR motif

  7. XM_006500657.2 → XP_006500720.1  protein LKAAEAR1 isoform X7

    See identical proteins and their annotated locations for XP_006500720.1

    Conserved Domains (1) summary
    pfam15478
    Location:55 → 190
    LKAAEAR; Family of unknown function with LKAAEAR motif

  8. XM_030251705.1 → XP_030107565.1  protein LKAAEAR1 isoform X2

    Conserved Domains (1) summary
    pfam15478
    Location:48 → 183
    LKAAEAR; Family of unknown function with LKAAEAR motif
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BIG2.2 GenPept UniProtKB/Swiss-Prot:Q8BIG2

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