Vstm2l V-set and transmembrane domain containing 2-like [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Vstm2lprovided by MGI
Official Full Name: V-set and transmembrane domain containing 2-likeprovided by MGI
Primary source: MGI:MGI:2685537
See related: Ensembl:ENSMUSG00000037843 AllianceGenome:MGI:2685537
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm691
Summary: Predicted to enable cell-cell adhesion mediator activity. Involved in negative regulation of neuron apoptotic process. Located in extracellular region. Orthologous to human VSTM2L (V-set and transmembrane domain containing 2 like). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in whole brain E14.5 (RPKM 27.6), CNS E14 (RPKM 27.4) and 9 other tissues See more
Orthologs: human all
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Genomic context

Location:: 2 H1; 2 78.48 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	2	NC_000068.8 (157756573..157786639)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	2	NC_000068.7 (157914653..157944719)

Chromosome 2 - NC_000068.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Gene trapped (1)
Endonuclease-mediated (1)

General gene information

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Markers

RH133129 (e-PCR)
- UniSTS:216412

D2Mit55 (e-PCR), detects polymorphism
- UniSTS:129450

Gene Ontology Provided by MGI

Process	Evidence Code	Pubs
involved_in negative regulation of neuron apoptotic process	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of neuron apoptotic process	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in extracellular region	IDA Inferred from Direct Assay more info	PubMed
located_in extracellular region	ISO Inferred from Sequence Orthology more info
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: V-set and transmembrane domain-containing protein 2-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_198627.2 → NP_941029.2 V-set and transmembrane domain-containing protein 2-like protein precursor

See identical proteins and their annotated locations for NP_941029.2

Status: VALIDATED

Source sequence(s)

BC058538, BF323097, BQ746346

Consensus CDS

CCDS50784.1

UniProtKB/TrEMBL

A2ACD2

Related

ENSMUSP00000105149.2, ENSMUST00000109523.2

Conserved Domains (2) summary

pfam13927
Location:43 → 144

Ig_3; Immunoglobulin domain

cd00096
Location:50 → 52

Ig; Ig strand A' [structural motif]