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Trp53i11 transformation related protein 53 inducible protein 11 [ Mus musculus (house mouse) ]

Gene ID: 277414, updated on 5-Mar-2024

Summary

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Official Symbol
Trp53i11provided by MGI
Official Full Name
transformation related protein 53 inducible protein 11provided by MGI
Primary source
MGI:MGI:2670995
See related
Ensembl:ENSMUSG00000068735 AllianceGenome:MGI:2670995
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tp53i11
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in nervous system and neural retina. Orthologous to human TP53I11 (tumor protein p53 inducible protein 11). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in thymus adult (RPKM 53.1), colon adult (RPKM 33.8) and 24 other tissues See more
Orthologs
human all
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Genomic context

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Location:
2 E1; 2 51.37 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (93017694..93032102)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (93187349..93201757)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700055L01 gene Neighboring gene predicted gene, 32627 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:93032831-93033064 Neighboring gene predicted gene, 32683 Neighboring gene tetraspanin 18 Neighboring gene predicted gene, 32824 Neighboring gene predicted gene, 39882

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells. Sabbagh MF, et al. Elife, 2018 Sep 6. PMID 30188322, Free PMC Article
  2. A dual-strategy expression screen for candidate connectivity labels in the developing thalamus. Bibollet-Bahena O, et al. PLoS One, 2017. PMID 28558017, Free PMC Article
  3. Genomic analysis of mouse retinal development. Blackshaw S, et al. PLoS Biol, 2004 Sep. PMID 15226823, Free PMC Article
  4. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
  5. A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Thompson CL, et al. Neuron, 2014 Jul 16. PMID 24952961, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
tumor protein p53-inducible protein 11
Names
Trp53 inducible protein 11 (Trp53i11)
p53-induced gene 11 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025246.3 → NP_001020417.1  tumor protein p53-inducible protein 11 isoform b

    See identical proteins and their annotated locations for NP_001020417.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an alternate exon in the 5' UTR and uses an alternate splice junction compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 3 and 4 both encode the same isoform (b).
    Source sequence(s)
    AL683882, AL691472
    Consensus CDS
    CCDS16452.1
    UniProtKB/Swiss-Prot
    Q3UQL4, Q4QQM4
    Related
    ENSMUSP00000088042.5, ENSMUST00000090554.11
    Conserved Domains (1) summary
    pfam14936
    Location:10 → 188
    p53-inducible11; tumor protein p53-inducible protein 11

  2. NM_001356535.2 → NP_001343464.1  tumor protein p53-inducible protein 11 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 both encode the same isoform (a).
    Source sequence(s)
    AL683882, AL691472
    Conserved Domains (1) summary
    pfam14936
    Location:25 → 203
    p53-inducible11; tumor protein p53-inducible protein 11

  3. NM_001356536.2 → NP_001343465.1  tumor protein p53-inducible protein 11 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (a).
    Source sequence(s)
    AL683882, AL691472
    Conserved Domains (1) summary
    pfam14936
    Location:25 → 203
    p53-inducible11; tumor protein p53-inducible protein 11

  4. NM_001356537.2 → NP_001343466.1  tumor protein p53-inducible protein 11 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate splice junction compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 3 and 4 both encode the same isoform (b).
    Source sequence(s)
    AL683882, AL691472
    Consensus CDS
    CCDS16452.1
    UniProtKB/Swiss-Prot
    Q3UQL4, Q4QQM4
    Related
    ENSMUST00000127173.2
    Conserved Domains (1) summary
    pfam14936
    Location:10 → 188
    p53-inducible11; tumor protein p53-inducible protein 11

RNA

  1. NR_151503.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 3' end compared to variant 1. This variant is represented as non-coding because it lacks the entire coding region found in variant 1.
    Source sequence(s)
    AL683882
    Related
    ENSMUST00000132182.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    93017694..93032102
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036162275.1 → XP_036018168.1  tumor protein p53-inducible protein 11 isoform X1

    Conserved Domains (1) summary
    pfam14936
    Location:25 → 203
    p53-inducible11; tumor protein p53-inducible protein 11

  2. XM_030251698.2 → XP_030107558.1  tumor protein p53-inducible protein 11 isoform X2

    UniProtKB/Swiss-Prot
    Q3UQL4, Q4QQM4
    Conserved Domains (1) summary
    pfam14936
    Location:10 → 188
    p53-inducible11; tumor protein p53-inducible protein 11

  3. XM_036162277.1 → XP_036018170.1  tumor protein p53-inducible protein 11 isoform X1

    Conserved Domains (1) summary
    pfam14936
    Location:25 → 203
    p53-inducible11; tumor protein p53-inducible protein 11

  4. XM_030251700.2 → XP_030107560.1  tumor protein p53-inducible protein 11 isoform X2

    UniProtKB/Swiss-Prot
    Q3UQL4, Q4QQM4
    Conserved Domains (1) summary
    pfam14936
    Location:10 → 188
    p53-inducible11; tumor protein p53-inducible protein 11

  5. XM_030251697.2 → XP_030107557.1  tumor protein p53-inducible protein 11 isoform X1

    Conserved Domains (1) summary
    pfam14936
    Location:25 → 203
    p53-inducible11; tumor protein p53-inducible protein 11

  6. XM_036162280.1 → XP_036018173.1  tumor protein p53-inducible protein 11 isoform X2

    UniProtKB/Swiss-Prot
    Q3UQL4, Q4QQM4
    Conserved Domains (1) summary
    pfam14936
    Location:10 → 188
    p53-inducible11; tumor protein p53-inducible protein 11

  7. XM_030251699.2 → XP_030107559.1  tumor protein p53-inducible protein 11 isoform X2

    UniProtKB/Swiss-Prot
    Q3UQL4, Q4QQM4
    Conserved Domains (1) summary
    pfam14936
    Location:10 → 188
    p53-inducible11; tumor protein p53-inducible protein 11

  8. XM_006499685.4 → XP_006499748.1  tumor protein p53-inducible protein 11 isoform X2

    See identical proteins and their annotated locations for XP_006499748.1

    UniProtKB/Swiss-Prot
    Q3UQL4, Q4QQM4
    Conserved Domains (1) summary
    pfam14936
    Location:10 → 188
    p53-inducible11; tumor protein p53-inducible protein 11

  9. XM_017318948.2 → XP_017174437.1  tumor protein p53-inducible protein 11 isoform X1

    Conserved Domains (1) summary
    pfam14936
    Location:25 → 203
    p53-inducible11; tumor protein p53-inducible protein 11

  10. XM_036162281.1 → XP_036018174.1  tumor protein p53-inducible protein 11 isoform X2

    UniProtKB/Swiss-Prot
    Q3UQL4, Q4QQM4
    Conserved Domains (1) summary
    pfam14936
    Location:10 → 188
    p53-inducible11; tumor protein p53-inducible protein 11

  11. XM_036162276.1 → XP_036018169.1  tumor protein p53-inducible protein 11 isoform X1

    Conserved Domains (1) summary
    pfam14936
    Location:25 → 203
    p53-inducible11; tumor protein p53-inducible protein 11

  12. XM_036162279.1 → XP_036018172.1  tumor protein p53-inducible protein 11 isoform X2

    UniProtKB/Swiss-Prot
    Q3UQL4, Q4QQM4
    Conserved Domains (1) summary
    pfam14936
    Location:10 → 188
    p53-inducible11; tumor protein p53-inducible protein 11

  13. XM_036162278.1 → XP_036018171.1  tumor protein p53-inducible protein 11 isoform X2

    UniProtKB/Swiss-Prot
    Q3UQL4, Q4QQM4
    Conserved Domains (1) summary
    pfam14936
    Location:10 → 188
    p53-inducible11; tumor protein p53-inducible protein 11

  14. XM_006499681.3 → XP_006499744.1  tumor protein p53-inducible protein 11 isoform X2

    See identical proteins and their annotated locations for XP_006499744.1

    UniProtKB/Swiss-Prot
    Q3UQL4, Q4QQM4
    Related
    ENSMUSP00000106897.2, ENSMUST00000111266.8
    Conserved Domains (1) summary
    pfam14936
    Location:10 → 188
    p53-inducible11; tumor protein p53-inducible protein 11
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4QQM4.1 GenPept UniProtKB/Swiss-Prot:Q4QQM4

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