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Atp5mg ATP synthase membrane subunit g [ Mus musculus (house mouse) ]

Gene ID: 27425, updated on 5-Mar-2024

Summary

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Official Symbol
Atp5mgprovided by MGI
Official Full Name
ATP synthase membrane subunit gprovided by MGI
Primary source
MGI:MGI:1351597
See related
Ensembl:ENSMUSG00000038717 AllianceGenome:MGI:1351597
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Atp5l; 4933437C06Rik
Summary
Predicted to enable P-type proton-exporting transporter activity. Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in ATP synthesis coupled proton transport. Predicted to act upstream of or within ATP biosynthetic process and ion transport. Located in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; central nervous system; cranium; eye; and genitourinary system. Orthologous to several human genes including ATP5MG (ATP synthase membrane subunit g). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in heart adult (RPKM 309.5), kidney adult (RPKM 211.8) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
9 A5.2; 9 24.84 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (44824546..44832470, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (44913248..44920742, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_23986 Neighboring gene predicted gene, 30883 Neighboring gene predicted gene, 26249 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:44728805-44728988 Neighboring gene predicted gene, 30934 Neighboring gene ubiquitination factor E4A Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class A pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:44773592-44773779 Neighboring gene CD3 antigen, gamma polypeptide

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Sequence of a cDNA encoding mouse F1F0-ATP synthase g subunit. Jeon D, et al. Biosci Biotechnol Biochem, 1999 Apr. PMID 10361692
  2. A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice. Toye AA, et al. Diabetologia, 2005 Apr. PMID 15729571
  3. Histone deacetylase 3 controls lung alveolar macrophage development and homeostasis. Yao Y, et al. Nat Commun, 2020 Jul 30. PMID 32732898, Free PMC Article
  4. Characterization of the zinc-induced Shank3 interactome of mouse synaptosome. Lee Y, et al. Biochem Biophys Res Commun, 2017 Dec 16. PMID 29111324
  5. Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome. Grose JH, et al. PLoS One, 2015. PMID 26465331, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (1) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC107313, MGC107547

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables P-type proton-exporting transporter activity ISO
Inferred from Sequence Orthology
more info
 PubMed 
enables proton transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
contributes_to proton-transporting ATP synthase activity, rotational mechanism IBA
Inferred from Biological aspect of Ancestor
more info
  
contributes_to proton-transporting ATP synthase activity, rotational mechanism ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within ATP biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in proton motive force-driven ATP synthesis IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within proton motive force-driven ATP synthesis ISO
Inferred from Sequence Orthology
more info
 PubMed 
acts_upstream_of_or_within proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial inner membrane HDA PubMed 
part_of mitochondrial proton-transporting ATP synthase complex ISO
Inferred from Sequence Orthology
more info
 PubMed 
part_of mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  
part_of proton-transporting ATP synthase complex, coupling factor F(o) IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ATP synthase subunit g, mitochondrial
Names
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit G
ATPase subunit g
F1F0-ATP synthase g subunit
NP_038823.2
XP_036010936.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013795.5 → NP_038823.2  ATP synthase subunit g, mitochondrial

    See identical proteins and their annotated locations for NP_038823.2

    Status: VALIDATED

    Source sequence(s)
    BC086880, BY269662
    Consensus CDS
    CCDS40604.1
    UniProtKB/Swiss-Prot
    O70590, Q5M9M8, Q9CPQ8
    UniProtKB/TrEMBL
    Q9D037
    Related
    ENSMUSP00000047960.8, ENSMUST00000043675.9
    Conserved Domains (1) summary
    pfam04718
    Location:10 → 101
    ATP-synt_G; Mitochondrial ATP synthase g subunit

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    44824546..44832470 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036155043.1 → XP_036010936.1  ATP synthase subunit g, mitochondrial isoform X1

    UniProtKB/Swiss-Prot
    O70590, Q5M9M8, Q9CPQ8
    UniProtKB/TrEMBL
    Q9D037
    Conserved Domains (1) summary
    pfam04718
    Location:10 → 101
    ATP-synt_G; Mitochondrial ATP synthase g subunit
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CPQ8.1 GenPept UniProtKB/Swiss-Prot:Q9CPQ8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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