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Smok2a sperm motility kinase 2A [ Mus musculus (house mouse) ]

Gene ID: 27263, updated on 11-Apr-2024

Summary

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Official Symbol
Smok2aprovided by MGI
Official Full Name
sperm motility kinase 2Aprovided by MGI
Primary source
MGI:MGI:1351487
See related
Ensembl:ENSMUSG00000073458 AllianceGenome:MGI:1351487
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Smok2
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and protein phosphorylation. Predicted to act upstream of or within phosphorylation. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 2.8) See more
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Genomic context

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Location:
17 A1; 17 8.82 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (13439959..13446701)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (13221188..13227658)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 36798 Neighboring gene predicted gene, 36684 Neighboring gene STARR-seq mESC enhancer starr_41871 Neighboring gene predicted gene 10512 Neighboring gene sperm motility kinase 2B Neighboring gene predicted gene, 26500

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The alliance for cellular signaling plasmid collection: a flexible resource for protein localization studies and signaling pathway analysis. Zavzavadjian JR, et al. Mol Cell Proteomics, 2007 Mar. PMID 17192258, Free PMC Article
  2. A protein kinase encoded by the t complex responder gene causes non-mendelian inheritance. Herrmann BG, et al. Nature, 1999 Nov 11. PMID 10647005
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in protein phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
sperm motility kinase 2A
Names
putative protein kinase
sperm motility kinase 2
NP_038769.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013741.2 → NP_038769.1  sperm motility kinase 2A

    See identical proteins and their annotated locations for NP_038769.1

    Status: VALIDATED

    Source sequence(s)
    AC166360
    Consensus CDS
    CCDS49951.1
    UniProtKB/Swiss-Prot
    Q9QYZ6
    UniProtKB/TrEMBL
    G5E8M0
    Related
    ENSMUSP00000094432.3, ENSMUST00000080647.5
    Conserved Domains (3) summary
    smart00220
    Location:28 → 276
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14337
    Location:295 → 334
    UBA_MARK_Par1; UBA domain found in microtubule-associated protein (MAP)/microtubule affinity-regulating kinase (MARK)/ partitioning-defective 1 (Par-1) and similar proteins
    cd14003
    Location:27 → 275
    STKc_AMPK-like; Catalytic domain of AMP-activated protein kinase-like Serine/Threonine Kinases

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    13439959..13446701
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9QYZ6.1 GenPept UniProtKB/Swiss-Prot:Q9QYZ6

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