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Srp9 signal recognition particle 9 [ Mus musculus (house mouse) ]

Gene ID: 27058, updated on 11-Apr-2024

Summary

Official Symbol
Srp9provided by MGI
Official Full Name
signal recognition particle 9provided by MGI
Primary source
MGI:MGI:1350930
See related
Ensembl:ENSMUSG00000026511 AllianceGenome:MGI:1350930
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9kDa
Summary
Predicted to enable 7S RNA binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane. Predicted to be located in cytoplasm. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and immune system. Orthologous to human SRP9 (signal recognition particle 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 43.4), testis adult (RPKM 34.4) and 28 other tissues See more
Orthologs
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Genomic context

Location:
1 H5; 1 84.93 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (181952302..181959980)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (182124737..182132415)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_03262 Neighboring gene nuclear encoded tRNA serine 1 (anticodon GCT) Neighboring gene predicted gene, 39719 Neighboring gene predicted gene, 33725 Neighboring gene STARR-positive B cell enhancer ABC_E7783 Neighboring gene STARR-positive B cell enhancer ABC_E11700 Neighboring gene STARR-positive B cell enhancer ABC_E3346 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene STARR-seq mESC enhancer starr_03268 Neighboring gene STARR-seq mESC enhancer starr_03269 Neighboring gene vomeronasal 1 receptor 1 Neighboring gene STARR-seq mESC enhancer starr_03270 Neighboring gene STARR-seq mESC enhancer starr_03273 Neighboring gene STARR-seq mESC enhancer starr_03274 Neighboring gene STARR-seq mESC enhancer starr_03276 Neighboring gene predicted gene, 33887

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables 7S RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in SRP-dependent cotranslational protein targeting to membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in negative regulation of translational elongation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 
part_of signal recognition particle IEA
Inferred from Electronic Annotation
more info
 
part_of signal recognition particle, endoplasmic reticulum targeting IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
signal recognition particle 9 kDa protein
NP_036188.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_012058.3NP_036188.1  signal recognition particle 9 kDa protein

    See identical proteins and their annotated locations for NP_036188.1

    Status: VALIDATED

    Source sequence(s)
    AK051208, AK146882, CJ047061
    Consensus CDS
    CCDS35812.1
    UniProtKB/Swiss-Prot
    P49962, Q9D085
    UniProtKB/TrEMBL
    Q3UIK3, Q5EAT0
    Related
    ENSMUSP00000027792.6, ENSMUST00000027792.6
    Conserved Domains (1) summary
    pfam05486
    Location:473
    SRP9-21; Signal recognition particle 9 kDa protein (SRP9)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    181952302..181959980
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)