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Cnpy1 canopy FGF signaling regulator 1 [ Mus musculus (house mouse) ]

Gene ID: 269637, updated on 21-Apr-2024

Summary

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Official Symbol
Cnpy1provided by MGI
Official Full Name
canopy FGF signaling regulator 1provided by MGI
Primary source
MGI:MGI:2442451
See related
Ensembl:ENSMUSG00000044681 AllianceGenome:MGI:2442451
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1500012D20Rik; 9630008K15Rik
Summary
Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including brain. Orthologous to human CNPY1 (canopy FGF signaling regulator 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in cerebellum adult (RPKM 59.1), CNS E11.5 (RPKM 25.1) and 3 other tissues See more
Orthologs
human all
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Genomic context

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Location:
5 B1; 5 13.99 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (28405817..28450786, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (28200819..28245788, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 42242 Neighboring gene predicted gene, 35395 Neighboring gene STARR-seq mESC enhancer starr_12715 Neighboring gene STARR-seq mESC enhancer starr_12716 Neighboring gene predicted gene, 35524 Neighboring gene predicted gene, 35602 Neighboring gene RNA binding motif protein 33

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Developmentally regulated Shh expression is robust to TAD perturbations. Williamson I, et al. Development, 2019 Sep 30. PMID 31511252, Free PMC Article
  2. Mapping the Shh long-range regulatory domain. Anderson E, et al. Development, 2014 Oct. PMID 25252942, Free PMC Article
  3. Increased β-catenin activity in the anterior neural plate induces ectopic mid-hindbrain characteristics. Paek H, et al. Dev Dyn, 2012 Feb. PMID 22102609, Free PMC Article
  4. Single-cell RNA-Seq reveals a highly coordinated transcriptional program in mouse germ cells during primordial follicle formation. He Y, et al. Aging Cell, 2021 Jul. PMID 34174788, Free PMC Article
  5. FGF regulated gene-expression and neuronal differentiation in the developing midbrain-hindbrain region. Jukkola T, et al. Dev Biol, 2006 Sep 1. PMID 16782087

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  

General protein information

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Preferred Names
protein canopy homolog 1
Names
canopy 1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001310511.1 → NP_001297440.1  protein canopy homolog 1

    See identical proteins and their annotated locations for NP_001297440.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC129184, AK139155, AK162570, BX630527
    Consensus CDS
    CCDS80237.1
    UniProtKB/Swiss-Prot
    Q4VAB4, Q8CBK9
    Related
    ENSMUSP00000113944.2, ENSMUST00000118882.2
    Conserved Domains (1) summary
    pfam11938
    Location:2 → 78
    DUF3456; TLR4 regulator and MIR-interacting MSAP

  2. NM_001310512.1 → NP_001297441.1  protein canopy homolog 1

    See identical proteins and their annotated locations for NP_001297441.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC129184, AK035938, BX630527
    Consensus CDS
    CCDS80237.1
    UniProtKB/Swiss-Prot
    Q4VAB4, Q8CBK9
    Conserved Domains (1) summary
    pfam11938
    Location:2 → 78
    DUF3456; TLR4 regulator and MIR-interacting MSAP

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    28405817..28450786 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_175651.4: Suppressed sequence

    Description
    NM_175651.4: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4VAB4.1 GenPept UniProtKB/Swiss-Prot:Q4VAB4

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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