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Wdr86 WD repeat domain 86 [ Mus musculus (house mouse) ]

Gene ID: 269633, updated on 9-Dec-2024

Summary

Official Symbol
Wdr86provided by MGI
Official Full Name
WD repeat domain 86provided by MGI
Primary source
MGI:MGI:1915466
See related
Ensembl:ENSMUSG00000055235 AllianceGenome:MGI:1915466
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2810046M22Rik
Summary
Is expressed in cerebral cortex ventricular layer; choroid plexus; meninges; and testis. Orthologous to human WDR86 (WD repeat domain 86). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Ubiquitous expression in limb E14.5 (RPKM 5.1), placenta adult (RPKM 3.7) and 27 other tissues See more
Orthologs
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Genomic context

See Wdr86 in Genome Data Viewer
Location:
5 A3; 5 11.93 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (24901898..24935696, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (24696900..24730698, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene chondroitin polymerizing factor 2 Neighboring gene SWI/SNF related BAF chromatin remodeling complex subunit D3 Neighboring gene glycerol-3-phosphate dehydrogenase 1-like pseudogene Neighboring gene STARR-seq mESC enhancer starr_12645 Neighboring gene STARR-positive B cell enhancer mm9_chr5:24180078-24180378 Neighboring gene STARR-positive B cell enhancer ABC_E1298 Neighboring gene STARR-positive B cell enhancer ABC_E11722 Neighboring gene negative regulator of ubiquitin-like proteins 1 Neighboring gene VISTA enhancer mm394 Neighboring gene predicted gene, 42231 Neighboring gene STARR-seq mESC enhancer starr_12647 Neighboring gene predicted gene, 33591 Neighboring gene crystallin, gamma N

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

General gene information

Gene Ontology Provided by MGI

Component Evidence Code Pubs
is_active_in cellular_component  

General protein information

Preferred Names
WD repeat-containing protein 86

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081441.1NP_001074910.1  WD repeat-containing protein 86

    See identical proteins and their annotated locations for NP_001074910.1

    Status: VALIDATED

    Source sequence(s)
    BC059069, BY712199, CA328147, CN527054, CN528185
    Consensus CDS
    CCDS39031.1
    UniProtKB/TrEMBL
    D3Z757
    Related
    ENSMUSP00000064785.6, ENSMUST00000068693.12
    Conserved Domains (4) summary
    smart00320
    Location:304341
    WD40; WD40 repeats
    COG2319
    Location:24345
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:8301
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:6195
    7WD40; WD40 repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    24901898..24935696 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006535720.5XP_006535783.1  WD repeat-containing protein 86 isoform X3

    Conserved Domains (2) summary
    cd00200
    Location:8284
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:6195
    7WD40; WD40 repeat [structural motif]
  2. XM_006535718.4XP_006535781.1  WD repeat-containing protein 86 isoform X1

    Conserved Domains (3) summary
    smart00320
    Location:334371
    WD40; WD40 repeats
    cd00200
    Location:8289
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:6195
    7WD40; WD40 repeat [structural motif]
  3. XM_006535719.4XP_006535782.1  WD repeat-containing protein 86 isoform X2

    Conserved Domains (2) summary
    cd00200
    Location:11327
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:1751
    7WD40; WD40 repeat [structural motif]

RNA

  1. XR_001784702.2 RNA Sequence

  2. XR_003955653.1 RNA Sequence

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