Nfasc neurofascin [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Nfascprovided by MGI
Official Full Name: neurofascinprovided by MGI
Primary source: MGI:MGI:104753
See related: Ensembl:ENSMUSG00000026442 AllianceGenome:MGI:104753
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: NF; mKIAA0756; D430023G06Rik
Summary: This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined. [provided by RefSeq, May 2009]
Expression: Biased expression in cerebellum adult (RPKM 16.4), cortex adult (RPKM 13.2) and 6 other tissues See more
Orthologs: human all
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Genomic context

Location:: 1 E4; 1 57.42 cM

Exon count:: 37

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	1	NC_000067.7 (132492428..132669567, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	1	NC_000067.6 (132564690..132741848, complement)

Chromosome 1 - NC_000067.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Neurofascin and Kv7.3 are delivered to somatic and axon terminal surface membranes en route to the axon initial segment.
Title: Neurofascin and Kv7.3 are delivered to somatic and axon terminal surface membranes en route to the axon initial segment.
Conditional deletion of the glial isoform Nfasc155 in mice causes severe motor coordination defects and death at 16-17 days after birth.
Title: Homozygous mutation in the Neurofascin gene affecting the glial isoform of Neurofascin causes severe neurodevelopment disorder with hypotonia, amimia and areflexia.
Study shows that simultaneous ablation of neuronal Neurofascin and Ankyrin G in young and adult mice reveals age-dependent increase in nodal stability in myelinated axons and differential effects on the lifespan.
Title: Simultaneous Ablation of Neuronal Neurofascin and Ankyrin G in Young and Adult Mice Reveals Age-Dependent Increase in Nodal Stability in Myelinated Axons and Differential Effects on the Lifespan.
we identify QKI as the long-sought regulator of Neurofascin alternative splicing
Title: Quaking Regulates Neurofascin 155 Expression for Myelin and Axoglial Junction Maintenance.
P0/NFasc Interaction critical for the integrity of paranodal/nodal structures, but not for the stability of myelin
Title: HDAC1/2-Dependent P0 Expression Maintains Paranodal and Nodal Integrity Independently of Myelin Stability through Interactions with Neurofascins.
Neurofascin 140 is essential for assembly of the node of Ranvier in embryogenesis.
Title: Neurofascin 140 is an embryonic neuronal neurofascin isoform that promotes the assembly of the node of Ranvier.
In embryonic mouse axons, AnkG is expressed at the beginning of axonogenesis at E9.5 and initially distributed homogeneously along the entire growing axon. From E11.5 the protein progressively becomes restricted to the proximal axon.
Title: In vivo assembly of the axon initial segment in motor neurons.
loss of Nfasc155 was sufficient to cause a robust delay in postnatal synapse elimination at the NMJ across all muscle groups examined.
Title: Loss of glial neurofascin155 delays developmental synapse elimination at the neuromuscular junction.
the apparent dependency on sulfatide for maintaining Nfasc155 and MAG associations is intriguing since the fatty acid composition of sulfatide is altered and paranodal ultrastructure is compromised in multiple sclerosis
Title: Nfasc155H and MAG are specifically susceptible to detergent extraction in the absence of the myelin sphingolipid sulfatide.
Neurofascin is O-mannosylated and the glycosylation sites have been mapped.
Title: Neurofascin 186 is O-mannosylated within and outside of the mucin domain.

Submit: New GeneRIF Correction See all GeneRIFs (19)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Gene trapped (1)
Targeted (6) 1 citation
Endonuclease-mediated (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH132614 (e-PCR)
- UniSTS:215897

RH144666 (e-PCR)
- UniSTS:233911

NoName (e-PCR)
- UniSTS:234213

NoName (e-PCR)
- UniSTS:234218

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables cell-cell adhesion mediator activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein binding involved in heterotypic cell-cell adhesion	IGI Inferred from Genetic Interaction more info	PubMed
enables protein domain specific binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in axon guidance	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within axon guidance	IDA Inferred from Direct Assay more info	PubMed
involved_in brain development	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within cell adhesion	IEA Inferred from Electronic Annotation more info
involved_in cell-cell adhesion	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within clustering of voltage-gated sodium channels	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within paranodal junction assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in paranodal junction assembly	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within protein localization to juxtaparanode region of axon	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within protein localization to paranode region of axon	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein localization to plasma membrane	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within synapse organization	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within transmission of nerve impulse	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in Schwann cell microvillus	ISO Inferred from Sequence Orthology more info
is_active_in axon	IBA Inferred from Biological aspect of Ancestor more info
located_in axon	IDA Inferred from Direct Assay more info	PubMed
located_in axon	ISO Inferred from Sequence Orthology more info
located_in axon initial segment	IDA Inferred from Direct Assay more info	PubMed
located_in axon initial segment	ISO Inferred from Sequence Orthology more info
located_in dendrite	ISO Inferred from Sequence Orthology more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in myelin sheath	HDA more info	PubMed
located_in node of Ranvier	IDA Inferred from Direct Assay more info	PubMed
colocalizes_with node of Ranvier	ISO Inferred from Sequence Orthology more info
located_in node of Ranvier	ISO Inferred from Sequence Orthology more info
located_in paranodal junction	IDA Inferred from Direct Assay more info	PubMed
located_in paranode region of axon	IDA Inferred from Direct Assay more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	TAS Traceable Author Statement more info
located_in septate junction	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: neurofascin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001160316.1 → NP_001153788.1 neurofascin isoform 2 precursor

Status: REVIEWED

Description

Transcript Variant: This variant (2) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The promoter and 5' UTR for this variant have not been determined. The resulting isoform (2) includes the third fibronectin type 3 (FNIII) repeat, lacks the mucin-like domain, and has several differences near the N-terminus, compared to isoform 1. Isoform 2 is also known as NF155, as described by Davis et al. (PMID: 8947556).

Source sequence(s)

AC116691, AC159974, AI847023

UniProtKB/TrEMBL

A0A087WR56

Related

ENSMUSP00000140480.2, ENSMUST00000186389.7

Conserved Domains (8) summary

cd05731
Location:275 → 345

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

cd05875
Location:53 → 129

Ig6_hNeurofascin_like; Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF)

smart00408
Location:460 → 519

IGc2; Immunoglobulin C-2 Type

smart00410
Location:264 → 344

IG_like; Immunoglobulin like

cd00063
Location:639 → 729

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam07679
Location:539 → 620

I-set; Immunoglobulin I-set domain

pfam13882
Location:1081 → 1165

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:134 → 226

Ig; Immunoglobulin domain
NM_001160317.1 → NP_001153789.1 neurofascin isoform 3 precursor

Status: REVIEWED

Description

Transcript Variant: This variant (3) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The resulting isoform (3) includes the third fibronectin type 3 (FNIII) repeat, lacks the mucin-like domain, and has several differences in the N-terminal and central regions, compared to isoform 1.

Source sequence(s)

AC159974, AI847023, AK129207, AK138636, BB659942, BC062092

Consensus CDS

CCDS48359.1

UniProtKB/TrEMBL

A0A087WR56, E9PW06

Related

ENSMUSP00000132979.2, ENSMUST00000163770.8

Conserved Domains (8) summary

cd05731
Location:275 → 345

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

cd05875
Location:53 → 129

Ig6_hNeurofascin_like; Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF)

smart00408
Location:460 → 519

IGc2; Immunoglobulin C-2 Type

smart00410
Location:264 → 344

IG_like; Immunoglobulin like

cd00063
Location:624 → 714

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam07679
Location:539 → 620

I-set; Immunoglobulin I-set domain

pfam13882
Location:1066 → 1150

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:134 → 226

Ig; Immunoglobulin domain
NM_001160318.1 → NP_001153790.1 neurofascin isoform 4 precursor

Status: REVIEWED

Description

Transcript Variant: This variant (4) represents use of an alternate promoter and 5' UTR, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The resulting isoform (4) includes the third fibronectin type 3 (FNIII) repeat, lacks the mucin-like domain, and lacks two segments in the N-terminal and central regions, compared to isoform 1.

Source sequence(s)

AC159974, AI847023, AK129207, BC062092

Consensus CDS

CCDS48358.1

UniProtKB/TrEMBL

A0A087WR56, E9Q171

Related

ENSMUSP00000035454.8, ENSMUST00000043189.14

Conserved Domains (8) summary

cd05731
Location:258 → 328

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

cd05875
Location:53 → 129

Ig6_hNeurofascin_like; Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF)

smart00408
Location:443 → 502

IGc2; Immunoglobulin C-2 Type

smart00410
Location:247 → 327

IG_like; Immunoglobulin like

cd00063
Location:607 → 697

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam07679
Location:522 → 603

I-set; Immunoglobulin I-set domain

pfam13882
Location:1049 → 1133

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:134 → 226

Ig; Immunoglobulin domain
NM_182716.4 → NP_874385.1 neurofascin isoform 1 precursor

See identical proteins and their annotated locations for NP_874385.1

Status: REVIEWED

Description

Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). This isoform lacks the third fibronectin type 3 (FNIII) repeat and includes the mucin-like domain. Isoform 1 is also known as NF186, as described by Davis et al. (PMID: 8947556).

Source sequence(s)

AC116691, AC124095, AC159974, AI847023

Consensus CDS

CCDS35707.1

UniProtKB/Swiss-Prot

Q810U3

UniProtKB/TrEMBL

A0A087WR56

Related

ENSMUSP00000092148.5, ENSMUST00000094569.11

Conserved Domains (10) summary

cd05731
Location:264 → 334

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

cd05875
Location:59 → 135

Ig6_hNeurofascin_like; Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF)

smart00408
Location:449 → 508

IGc2; Immunoglobulin C-2 Type

smart00060
Location:729 → 810

FN3; Fibronectin type 3 domain

smart00410
Location:253 → 333

IG_like; Immunoglobulin like

cd00063
Location:628 → 718

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam07679
Location:528 → 609

I-set; Immunoglobulin I-set domain

pfam00041
Location:1015 → 1086

fn3; Fibronectin type III domain

pfam13882
Location:1132 → 1216

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:140 → 232

Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000067.7 Reference GRCm39 C57BL/6J

Range

132492428..132669567 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_036165385.1 → XP_036021278.1 neurofascin isoform X27

UniProtKB/TrEMBL

Q6ZQ54

Conserved Domains (7) summary

cd00063
Location:730 → 820

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam13882
Location:1060 → 1140

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:456 → 460

Ig; Ig strand B [structural motif]

cd05731
Location:354 → 436

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains

cd05845
Location:246 → 336

IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05875
Location:143 → 237

IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:440 → 528

Ig; Immunoglobulin domain
XM_006529635.4 → XP_006529698.2 neurofascin isoform X4

UniProtKB/TrEMBL

Q6ZQ54

Conserved Domains (7) summary

cd05875
Location:161 → 237

Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)

smart00060
Location:831 → 912

FN3; Fibronectin type 3 domain

cd00063
Location:730 → 820

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00096
Location:551 → 617

Ig; Immunoglobulin domain

cd05731
Location:366 → 436

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

pfam13882
Location:1341 → 1421

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:242 → 334

Ig; Immunoglobulin domain
XM_006529653.5 → XP_006529716.2 neurofascin isoform X18

UniProtKB/TrEMBL

Q6ZQ54

Conserved Domains (6) summary

cd05875
Location:155 → 231

Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)

cd00063
Location:709 → 799

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00096
Location:545 → 611

Ig; Immunoglobulin domain

cd05731
Location:360 → 430

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

pfam13882
Location:1151 → 1231

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:236 → 328

Ig; Immunoglobulin domain
XM_030254521.2 → XP_030110381.1 neurofascin isoform X7

UniProtKB/TrEMBL

Q6ZQ54

Conserved Domains (7) summary

cd05875
Location:155 → 231

Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)

smart00060
Location:810 → 891

FN3; Fibronectin type 3 domain

cd00063
Location:709 → 799

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00096
Location:545 → 611

Ig; Immunoglobulin domain

cd05731
Location:360 → 430

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

pfam13882
Location:1320 → 1400

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:236 → 328

Ig; Immunoglobulin domain
XM_011248013.4 → XP_011246315.1 neurofascin isoform X6

UniProtKB/TrEMBL

Q6ZQ54

Conserved Domains (7) summary

cd05875
Location:155 → 231

Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)

smart00060
Location:825 → 906

FN3; Fibronectin type 3 domain

cd00063
Location:724 → 814

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00096
Location:545 → 611

Ig; Immunoglobulin domain

cd05731
Location:360 → 430

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

pfam13882
Location:1335 → 1415

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:236 → 328

Ig; Immunoglobulin domain
XM_030254559.2 → XP_030110419.1 neurofascin isoform X28

UniProtKB/TrEMBL

Q6ZQ54

Conserved Domains (6) summary

cd05875
Location:155 → 231

Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)

cd00063
Location:726 → 816

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00096
Location:562 → 628

Ig; Immunoglobulin domain

cd05731
Location:377 → 447

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

pfam13882
Location:1056 → 1136

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:236 → 328

Ig; Immunoglobulin domain
XM_006529651.4 → XP_006529714.2 neurofascin isoform X16

UniProtKB/TrEMBL

Q6ZQ54

Conserved Domains (6) summary

cd05875
Location:155 → 231

Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)

cd00063
Location:726 → 816

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00096
Location:562 → 628

Ig; Immunoglobulin domain

cd05731
Location:377 → 447

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

pfam13882
Location:1163 → 1243

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:236 → 328

Ig; Immunoglobulin domain
XM_030254517.2 → XP_030110377.1 neurofascin isoform X5

UniProtKB/TrEMBL

Q6ZQ54

Conserved Domains (7) summary

cd05875
Location:155 → 231

Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)

smart00060
Location:827 → 908

FN3; Fibronectin type 3 domain

cd00063
Location:726 → 816

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00096
Location:562 → 628

Ig; Immunoglobulin domain

cd05731
Location:377 → 447

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

pfam13882
Location:1337 → 1417

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:236 → 328

Ig; Immunoglobulin domain
XM_006529646.4 → XP_006529709.2 neurofascin isoform X13

UniProtKB/TrEMBL

Q6ZQ54

Conserved Domains (6) summary

cd05875
Location:155 → 231

Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)

cd00063
Location:741 → 831

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00096
Location:562 → 628

Ig; Immunoglobulin domain

cd05731
Location:377 → 447

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

pfam13882
Location:1183 → 1263

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:236 → 328

Ig; Immunoglobulin domain
XM_011248011.3 → XP_011246313.1 neurofascin isoform X2

UniProtKB/TrEMBL

Q6ZQ54

Conserved Domains (7) summary

cd05875
Location:155 → 231

Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)

smart00060
Location:842 → 923

FN3; Fibronectin type 3 domain

cd00063
Location:741 → 831

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00096
Location:562 → 628

Ig; Immunoglobulin domain

cd05731
Location:377 → 447

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

pfam13882
Location:1352 → 1432

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:236 → 328

Ig; Immunoglobulin domain
XM_017320902.2 → XP_017176391.1 neurofascin isoform X26

UniProtKB/TrEMBL

Q6ZQ54

Conserved Domains (6) summary

cd05875
Location:161 → 237

Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)

cd00063
Location:732 → 822

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00096
Location:568 → 634

Ig; Immunoglobulin domain

cd05731
Location:383 → 453

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

pfam13882
Location:1062 → 1142

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:242 → 334

Ig; Immunoglobulin domain
XM_030254536.2 → XP_030110396.1 neurofascin isoform X15

UniProtKB/TrEMBL

Q6ZQ54

Conserved Domains (6) summary

cd05875
Location:161 → 237

Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)

cd00063
Location:732 → 822

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00096
Location:568 → 634

Ig; Immunoglobulin domain

cd05731
Location:383 → 453

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

pfam13882
Location:1169 → 1249

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:242 → 334

Ig; Immunoglobulin domain
XM_036165345.1 → XP_036021238.1 neurofascin isoform X14

UniProtKB/TrEMBL

Q6ZQ54

Conserved Domains (7) summary

cd00063
Location:732 → 822

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam13882
Location:1174 → 1254

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:473 → 477

Ig; Ig strand B [structural motif]

cd05731
Location:371 → 453

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains

cd05845
Location:246 → 336

IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05875
Location:143 → 237

IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:457 → 545

Ig; Immunoglobulin domain
XM_011248012.3 → XP_011246314.1 neurofascin isoform X3

UniProtKB/TrEMBL

Q6ZQ54

Conserved Domains (7) summary

cd05875
Location:161 → 237

Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)

smart00060
Location:833 → 914

FN3; Fibronectin type 3 domain

cd00063
Location:732 → 822

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00096
Location:568 → 634

Ig; Immunoglobulin domain

cd05731
Location:383 → 453

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

pfam13882
Location:1343 → 1423

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:242 → 334

Ig; Immunoglobulin domain
XM_017320900.2 → XP_017176389.1 neurofascin isoform X25

UniProtKB/TrEMBL

Q6ZQ54

Conserved Domains (6) summary

cd05875
Location:161 → 237

Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)

cd00063
Location:747 → 837

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00096
Location:568 → 634

Ig; Immunoglobulin domain

cd05731
Location:383 → 453

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

pfam13882
Location:1077 → 1157

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:242 → 334

Ig; Immunoglobulin domain
XM_036165357.1 → XP_036021250.1 neurofascin isoform X17

UniProtKB/TrEMBL

Q6ZQ54

Conserved Domains (8) summary

smart00060
Location:848 → 929

FN3; Fibronectin type 3 domain

cd00063
Location:747 → 837

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam13882
Location:1161 → 1241

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:473 → 477

Ig; Ig strand B [structural motif]

cd05731
Location:371 → 453

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains

cd05845
Location:246 → 336

IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05875
Location:143 → 237

IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:457 → 545

Ig; Immunoglobulin domain
XM_011248015.3 → XP_011246317.1 neurofascin isoform X10

UniProtKB/TrEMBL

Q6ZQ54

Conserved Domains (7) summary

cd05875
Location:161 → 237

Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)

smart00060
Location:848 → 929

FN3; Fibronectin type 3 domain

cd00063
Location:747 → 837

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00096
Location:568 → 634

Ig; Immunoglobulin domain

cd05731
Location:383 → 453

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

pfam13882
Location:1251 → 1331

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:242 → 334

Ig; Immunoglobulin domain
XM_011248017.3 → XP_011246319.1 neurofascin isoform X12

UniProtKB/TrEMBL

Q6ZQ54

Conserved Domains (6) summary

cd05875
Location:161 → 237

Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)

cd00063
Location:747 → 837

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00096
Location:568 → 634

Ig; Immunoglobulin domain

cd05731
Location:383 → 453

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

pfam13882
Location:1184 → 1264

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:242 → 334

Ig; Immunoglobulin domain
XM_006529644.4 → XP_006529707.2 neurofascin isoform X11

UniProtKB/TrEMBL

Q6ZQ54

Conserved Domains (6) summary

cd05875
Location:161 → 237

Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)

cd00063
Location:747 → 837

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00096
Location:568 → 634

Ig; Immunoglobulin domain

cd05731
Location:383 → 453

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

pfam13882
Location:1189 → 1269

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:242 → 334

Ig; Immunoglobulin domain
XM_006529639.5 → XP_006529702.2 neurofascin isoform X8

UniProtKB/TrEMBL

Q6ZQ54

Conserved Domains (7) summary

cd05875
Location:161 → 237

Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)

smart00060
Location:848 → 929

FN3; Fibronectin type 3 domain

cd00063
Location:747 → 837

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00096
Location:568 → 634

Ig; Immunoglobulin domain

cd05731
Location:383 → 453

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

pfam13882
Location:1279 → 1359

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:242 → 334

Ig; Immunoglobulin domain
XM_011248014.3 → XP_011246316.1 neurofascin isoform X9

UniProtKB/TrEMBL

Q6ZQ54

Conserved Domains (6) summary

cd05875
Location:161 → 237

Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)

cd00063
Location:747 → 837

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00096
Location:568 → 634

Ig; Immunoglobulin domain

cd05731
Location:383 → 453

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

pfam13882
Location:1268 → 1348

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:242 → 334

Ig; Immunoglobulin domain
XM_006529634.4 → XP_006529697.2 neurofascin isoform X1

UniProtKB/TrEMBL

Q6ZQ54

Conserved Domains (7) summary

cd05875
Location:161 → 237

Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)

smart00060
Location:848 → 929

FN3; Fibronectin type 3 domain

cd00063
Location:747 → 837

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00096
Location:568 → 634

Ig; Immunoglobulin domain

cd05731
Location:383 → 453

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

pfam13882
Location:1358 → 1438

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:242 → 334

Ig; Immunoglobulin domain
XM_030254557.2 → XP_030110417.1 neurofascin isoform X23

UniProtKB/TrEMBL

A0A087WR56

Conserved Domains (9) summary

smart00060
Location:723 → 804

FN3; Fibronectin type 3 domain

cd00063
Location:622 → 712

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:1115 → 1187

fn3; Fibronectin type III domain

pfam13882
Location:1233 → 1313

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:348 → 352

Ig; Ig strand B [structural motif]

cd05731
Location:246 → 328

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains

cd05845
Location:138 → 228

IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05875
Location:35 → 129

IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:332 → 420

Ig; Immunoglobulin domain
XM_011248021.1 → XP_011246323.1 neurofascin isoform X20

See identical proteins and their annotated locations for XP_011246323.1

UniProtKB/TrEMBL

A0A087WR56

Conserved Domains (9) summary

smart00060
Location:740 → 821

FN3; Fibronectin type 3 domain

cd00063
Location:639 → 729

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:1132 → 1204

fn3; Fibronectin type III domain

pfam13882
Location:1250 → 1330

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:365 → 369

Ig; Ig strand B [structural motif]

cd05731
Location:263 → 345

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains

cd05845
Location:138 → 228

IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05875
Location:35 → 129

IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:349 → 437

Ig; Immunoglobulin domain
XM_011248019.2 → XP_011246321.1 neurofascin isoform X19

See identical proteins and their annotated locations for XP_011246321.1

UniProtKB/TrEMBL

A0A087WR56

Conserved Domains (9) summary

smart00060
Location:746 → 827

FN3; Fibronectin type 3 domain

cd00063
Location:645 → 735

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:1138 → 1210

fn3; Fibronectin type III domain

pfam13882
Location:1256 → 1336

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:371 → 375

Ig; Ig strand B [structural motif]

cd05731
Location:269 → 351

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains

cd05845
Location:144 → 234

IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05875
Location:41 → 135

IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:355 → 443

Ig; Immunoglobulin domain
XM_030254547.1 → XP_030110407.1 neurofascin isoform X20

UniProtKB/TrEMBL

A0A087WR56

Conserved Domains (9) summary

smart00060
Location:740 → 821

FN3; Fibronectin type 3 domain

cd00063
Location:639 → 729

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:1132 → 1204

fn3; Fibronectin type III domain

pfam13882
Location:1250 → 1330

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:365 → 369

Ig; Ig strand B [structural motif]

cd05731
Location:263 → 345

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains

cd05845
Location:138 → 228

IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05875
Location:35 → 129

IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:349 → 437

Ig; Immunoglobulin domain
XM_030254549.2 → XP_030110409.1 neurofascin isoform X21

UniProtKB/TrEMBL

A0A087WPX3, A0A087WR56

Related

ENSMUSP00000139955.2, ENSMUST00000187861.7

Conserved Domains (7) summary

cd05875
Location:59 → 135

Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)

smart00060
Location:729 → 810

FN3; Fibronectin type 3 domain

cd00063
Location:628 → 718

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00096
Location:449 → 515

Ig; Immunoglobulin domain

cd05731
Location:264 → 334

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

pfam13882
Location:1239 → 1319

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:140 → 232

Ig; Immunoglobulin domain
XM_011248024.4 → XP_011246326.1 neurofascin isoform X19

See identical proteins and their annotated locations for XP_011246326.1

UniProtKB/TrEMBL

A0A087WR56

Conserved Domains (9) summary

smart00060
Location:746 → 827

FN3; Fibronectin type 3 domain

cd00063
Location:645 → 735

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:1138 → 1210

fn3; Fibronectin type III domain

pfam13882
Location:1256 → 1336

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:371 → 375

Ig; Ig strand B [structural motif]

cd05731
Location:269 → 351

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains

cd05845
Location:144 → 234

IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05875
Location:41 → 135

IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:355 → 443

Ig; Immunoglobulin domain
XM_036165375.1 → XP_036021268.1 neurofascin isoform X23

UniProtKB/TrEMBL

A0A087WR56

Conserved Domains (9) summary

smart00060
Location:723 → 804

FN3; Fibronectin type 3 domain

cd00063
Location:622 → 712

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:1115 → 1187

fn3; Fibronectin type III domain

pfam13882
Location:1233 → 1313

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:348 → 352

Ig; Ig strand B [structural motif]

cd05731
Location:246 → 328

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains

cd05845
Location:138 → 228

IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05875
Location:35 → 129

IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:332 → 420

Ig; Immunoglobulin domain
XM_011248020.4 → XP_011246322.1 neurofascin isoform X20

See identical proteins and their annotated locations for XP_011246322.1

UniProtKB/TrEMBL

A0A087WR56

Conserved Domains (9) summary

smart00060
Location:740 → 821

FN3; Fibronectin type 3 domain

cd00063
Location:639 → 729

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:1132 → 1204

fn3; Fibronectin type III domain

pfam13882
Location:1250 → 1330

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:365 → 369

Ig; Ig strand B [structural motif]

cd05731
Location:263 → 345

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains

cd05845
Location:138 → 228

IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05875
Location:35 → 129

IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:349 → 437

Ig; Immunoglobulin domain
XM_036165362.1 → XP_036021255.1 neurofascin isoform X19

UniProtKB/TrEMBL

A0A087WR56

Conserved Domains (9) summary

smart00060
Location:746 → 827

FN3; Fibronectin type 3 domain

cd00063
Location:645 → 735

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:1138 → 1210

fn3; Fibronectin type III domain

pfam13882
Location:1256 → 1336

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:371 → 375

Ig; Ig strand B [structural motif]

cd05731
Location:269 → 351

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains

cd05845
Location:144 → 234

IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05875
Location:41 → 135

IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:355 → 443

Ig; Immunoglobulin domain
XM_011248023.2 → XP_011246325.1 neurofascin isoform X19

See identical proteins and their annotated locations for XP_011246325.1

UniProtKB/TrEMBL

A0A087WR56

Conserved Domains (9) summary

smart00060
Location:746 → 827

FN3; Fibronectin type 3 domain

cd00063
Location:645 → 735

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:1138 → 1210

fn3; Fibronectin type III domain

pfam13882
Location:1256 → 1336

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:371 → 375

Ig; Ig strand B [structural motif]

cd05731
Location:269 → 351

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains

cd05845
Location:144 → 234

IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05875
Location:41 → 135

IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:355 → 443

Ig; Immunoglobulin domain
XM_030254562.1 → XP_030110422.1 neurofascin isoform X29

UniProtKB/TrEMBL

A0A087WR56

Conserved Domains (6) summary

cd05875
Location:53 → 129

Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)

cd00063
Location:624 → 714

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00096
Location:460 → 526

Ig; Immunoglobulin domain

cd05731
Location:275 → 345

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

pfam13882
Location:1061 → 1141

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:134 → 226

Ig; Immunoglobulin domain
XM_030254551.1 → XP_030110411.1 neurofascin isoform X22

UniProtKB/TrEMBL

A0A087WR56

Conserved Domains (7) summary

cd05875
Location:53 → 129

Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)

smart00060
Location:725 → 806

FN3; Fibronectin type 3 domain

cd00063
Location:624 → 714

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00096
Location:460 → 526

Ig; Immunoglobulin domain

cd05731
Location:275 → 345

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

pfam13882
Location:1235 → 1315

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:134 → 226

Ig; Immunoglobulin domain
XM_036165369.1 → XP_036021262.1 neurofascin isoform X20

UniProtKB/TrEMBL

A0A087WR56

Conserved Domains (9) summary

smart00060
Location:740 → 821

FN3; Fibronectin type 3 domain

cd00063
Location:639 → 729

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:1132 → 1204

fn3; Fibronectin type III domain

pfam13882
Location:1250 → 1330

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:365 → 369

Ig; Ig strand B [structural motif]

cd05731
Location:263 → 345

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains

cd05845
Location:138 → 228

IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05875
Location:35 → 129

IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:349 → 437

Ig; Immunoglobulin domain
XM_036165381.1 → XP_036021274.1 neurofascin isoform X24

UniProtKB/TrEMBL

A0A087WR56

Conserved Domains (9) summary

smart00060
Location:708 → 789

FN3; Fibronectin type 3 domain

cd00063
Location:607 → 697

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:1100 → 1172

fn3; Fibronectin type III domain

pfam13882
Location:1218 → 1298

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:348 → 352

Ig; Ig strand B [structural motif]

cd05731
Location:246 → 328

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains

cd05845
Location:138 → 228

IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05875
Location:35 → 129

IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:332 → 420

Ig; Immunoglobulin domain
XM_011248025.3 → XP_011246327.1 neurofascin isoform X30

Conserved Domains (5) summary

smart00060
Location:388 → 469

FN3; Fibronectin type 3 domain

cd00063
Location:287 → 377

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00096
Location:108 → 174

Ig; Immunoglobulin domain

pfam13882
Location:898 → 978

Bravo_FIGEY; Bravo-like intracellular region

cl11960
Location:39 → 85

Ig; Immunoglobulin domain
XM_017320909.3 → XP_017176398.1 neurofascin isoform X31

UniProtKB/TrEMBL

A0A9Y2YA21

Conserved Domains (4) summary

cd05875
Location:161 → 237

Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)

cd00096
Location:568 → 634

Ig; Immunoglobulin domain

cd05731
Location:383 → 453

Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)

cl11960
Location:242 → 334

Ig; Immunoglobulin domain