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Klhl38 kelch-like 38 [ Mus musculus (house mouse) ]

Gene ID: 268807, updated on 5-Mar-2024

Summary

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Official Symbol
Klhl38provided by MGI
Official Full Name
kelch-like 38provided by MGI
Primary source
MGI:MGI:3045310
See related
Ensembl:ENSMUSG00000022357 AllianceGenome:MGI:3045310
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
8230402K04Rik
Summary
Orthologous to human KLHL38 (kelch like family member 38). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in heart adult (RPKM 7.9), mammary gland adult (RPKM 1.8) and 5 other tissues See more
Orthologs
human all
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Genomic context

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Location:
15 D1; 15 24.62 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (58176076..58187623, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (58314573..58324169, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 36112 Neighboring gene F-box protein 32 Neighboring gene predicted gene, 36193 Neighboring gene STARR-seq mESC enhancer starr_38751 Neighboring gene STARR-seq mESC enhancer starr_38752 Neighboring gene STARR-seq mESC enhancer starr_38753 Neighboring gene predicted gene, 53238 Neighboring gene annexin A13 Neighboring gene STARR-positive B cell enhancer ABC_E7369 Neighboring gene STARR-seq mESC enhancer starr_38755 Neighboring gene family with sequence similarity 91, member A1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. KLHL38 facilitates staurosporine-induced apoptosis in HL-1 cells via myocardin degradation. Luo Y, et al. IUBMB Life, 2022 May. PMID 35112472
  2. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. KLHL38 facilitates staurosporine-induced apoptosis in HL-1 cells via myocardin degradation.
    Title: KLHL38 facilitates staurosporine-induced apoptosis in HL-1 cells via myocardin degradation.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
kelch-like protein 38

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177755.3 → NP_808423.1  kelch-like protein 38

    See identical proteins and their annotated locations for NP_808423.1

    Status: PROVISIONAL

    Source sequence(s)
    AK033353
    Consensus CDS
    CCDS27492.1
    UniProtKB/Swiss-Prot
    Q8BSF5
    Related
    ENSMUSP00000022985.2, ENSMUST00000022985.2
    Conserved Domains (7) summary
    smart00612
    Location:480 → 521
    Kelch; Kelch domain
    PHA03098
    Location:48 → 560
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:373 → 417
    Kelch; KELCH repeat [structural motif]
    pfam00651
    Location:24 → 128
    BTB; BTB/POZ domain
    pfam01344
    Location:510 → 560
    Kelch_1; Kelch motif
    pfam07707
    Location:136 → 237
    BACK; BTB And C-terminal Kelch
    pfam13964
    Location:281 → 321
    Kelch_6; Kelch motif

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    58176076..58187623 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036159434.1 → XP_036015327.1  kelch-like protein 38 isoform X1

    Conserved Domains (4) summary
    PHA03098
    Location:48 → 438
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:322 → 370
    Kelch; KELCH repeat [structural motif]
    cd18476
    Location:131 → 229
    BACK_KLHL38; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 38 (KLHL38)
    cl38908
    Location:11 → 139
    BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BSF5.1 GenPept UniProtKB/Swiss-Prot:Q8BSF5

Gene LinkOut

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