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EHF ETS homologous factor [ Homo sapiens (human) ]

Gene ID: 26298, updated on 5-Mar-2024

Summary

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Official Symbol
EHFprovided by HGNC
Official Full Name
ETS homologous factorprovided by HGNC
Primary source
HGNC:HGNC:3246
See related
Ensembl:ENSG00000135373 MIM:605439; AllianceGenome:HGNC:3246
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ESE3; ESEJ; ESE3B
Summary
This gene encodes a protein that belongs to an ETS transcription factor subfamily characterized by epithelial-specific expression (ESEs). The encoded protein acts as a transcriptional repressor and may be involved in epithelial differentiation and carcinogenesis. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Expression
Biased expression in esophagus (RPKM 89.9), colon (RPKM 60.6) and 12 other tissues See more
Orthologs
mouse all
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Genomic context

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See EHF in Genome Data Viewer
Location:
11p13
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (34621093..34663288)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (34757923..34800105)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (34642640..34684835)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:34517695-34518194 Neighboring gene E74 like ETS transcription factor 5 Neighboring gene Sharpr-MPRA regulatory region 13672 Neighboring gene long intergenic non-protein coding RNA 2707 Neighboring gene Sharpr-MPRA regulatory region 2953 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:34620676-34621875 Neighboring gene Sharpr-MPRA regulatory region 12213 Neighboring gene CRISPRi-validated cis-regulatory element chr11.1780 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4605 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4606 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr11:34701712-34702911 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:34706267-34707466 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:34713481-34714124 Neighboring gene uncharacterized LOC102723568 Neighboring gene NADH:ubiquinone oxidoreductase subunit B8 pseudogene 3 Neighboring gene Sharpr-MPRA regulatory region 2558 Neighboring gene NANOG hESC enhancer GRCh37_chr11:34817013-34817561 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3252 Neighboring gene uncharacterized LOC105376625

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Ese-3 Inhibits the Proliferation, Migration, and Invasion of HaCaT Cells by Downregulating PSIP1 and NUCKS1. Zhang C, et al. Ann Clin Lab Sci, 2021 Jul. PMID 34452885
  2. EHF enhances malignancy by modulating AKT and MAPK/ERK signaling in non‑small cell lung cancer cells. Gao L, et al. Oncol Rep, 2021 Jun. PMID 33907840, Free PMC Article
  3. Loss of EHF facilitates the development of treatment-induced neuroendocrine prostate cancer. Long Z, et al. Cell Death Dis, 2021 Jan 5. PMID 33414441, Free PMC Article
  4. Expression and prognostic significance of epithelial tissue-specific transcription factor ESE3 in hepatocellular carcinoma. Lyu Z, et al. Int J Clin Oncol, 2020 Jul. PMID 32347431
  5. Tumoral EHF predicts the efficacy of anti-PD1 therapy in pancreatic ductal adenocarcinoma. Liu J, et al. J Exp Med, 2019 Mar 4. PMID 30733283, Free PMC Article

See all (69) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Pancreatic cancer cell-derived microRNA-155-5p-containing extracellular vesicles promote immune evasion by triggering EHF-dependent activation of Akt/NF-kappaB signaling pathway.
    Title: Pancreatic cancer cell-derived microRNA-155-5p-containing extracellular vesicles promote immune evasion by triggering EHF-dependent activation of Akt/NF-κB signaling pathway.
  2. EHF enhances malignancy by modulating AKT and MAPK/ERK signaling in nonsmall cell lung cancer cells.
    Title: EHF enhances malignancy by modulating AKT and MAPK/ERK signaling in non‑small cell lung cancer cells.
  3. Loss of EHF facilitates the development of treatment-induced neuroendocrine prostate cancer.
    Title: Loss of EHF facilitates the development of treatment-induced neuroendocrine prostate cancer.
  4. Ese-3 Inhibits the Proliferation, Migration, and Invasion of HaCaT Cells by Downregulating PSIP1 and NUCKS1.
    Title: Ese-3 Inhibits the Proliferation, Migration, and Invasion of HaCaT Cells by Downregulating PSIP1 and NUCKS1.
  5. Activation of EHF via STAT3 phosphorylation by LMP2A in Epstein-Barr virus-positive gastric cancer.
    Title: Activation of EHF via STAT3 phosphorylation by LMP2A in Epstein-Barr virus-positive gastric cancer.
  6. Expression and prognostic significance of epithelial tissue-specific transcription factor ESE3 in hepatocellular carcinoma.
    Title: Expression and prognostic significance of epithelial tissue-specific transcription factor ESE3 in hepatocellular carcinoma.
  7. Coordinate regulation of ELF5 and EHF at the chr11p13 CF modifier region.
    Title: Coordinate regulation of ELF5 and EHF at the chr11p13 CF modifier region.
  8. Tumoral EHF expression associates with the immune profile in human pancreatic ductal adenocarcinoma patients.EHF suppressed the transcription of TGFB1 and CSF2 by directly binding to their promoters.
    Title: Tumoral EHF predicts the efficacy of anti-PD1 therapy in pancreatic ductal adenocarcinoma.
  9. Targeting a novel miR-365-3p/EHF/KRT16/beta5-integrin/c-Met signaling pathway could improve treatment efficacy in OSCC.
    Title: A novel miR-365-3p/EHF/keratin 16 axis promotes oral squamous cell carcinoma metastasis, cancer stemness and drug resistance via enhancing β5-integrin/c-met signaling pathway.
  10. Human prostate tumors with IL-6 elevation and loss of ESE3/EHF were associated with STAT3 activation and displayed upregulation of genes related to cell adhesion, cancer stem-like and metastatic spread.
    Title: The ETS factor ESE3/EHF represses IL-6 preventing STAT3 activation and expansion of the prostate cancer stem-like compartment.
Submit: New GeneRIF Correction See all GeneRIFs (32)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.
EBI GWAS Catalog
Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study.
EBI GWAS Catalog
Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease.
EBI GWAS Catalog
Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2.
EBI GWAS Catalog
Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.
EBI GWAS Catalog
GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.
EBI GWAS Catalog
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA binding TAS
Traceable Author Statement
more info
 PubMed 
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific ISA
Inferred from Sequence Alignment
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in epithelial cell differentiation IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
  
part_of chromatin ISA
Inferred from Sequence Alignment
more info
  
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IC
Inferred by Curator
more info
 PubMed 

General protein information

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Preferred Names
ETS homologous factor
Names
ESE3 transcription factor
ETS domain-containing transcription factor
epithelium-specific Ets transcription factor 3
hEHF

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_029177.2 RefSeqGene

    Range
    5002..47197
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001206615.2 → NP_001193544.1  ETS homologous factor isoform 3

    See identical proteins and their annotated locations for NP_001193544.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (3) is shorter at the N-terminus and lacks an internal segment compared to isoform 1. Variants 3 and 11 both encode the same isoform (3).
    Source sequence(s)
    AC087783
    Consensus CDS
    CCDS55753.1
    UniProtKB/Swiss-Prot
    Q9NZC4
    Related
    ENSP00000399733.2, ENST00000450654.6
    Conserved Domains (2) summary
    cd08539
    Location:39 → 116
    SAM_PNT-ESE-3-like; Sterile alpha motif (SAM)/Pointed domain of ESE-3 like ETS transcriptional regulators
    smart00413
    Location:183 → 270
    ETS; erythroblast transformation specific domain

  2. NM_001206616.2 → NP_001193545.1  ETS homologous factor isoform 1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AC087783
    Consensus CDS
    CCDS55752.1
    UniProtKB/Swiss-Prot
    Q9NZC4
    Related
    ENSP00000435835.1, ENST00000531794.5
    Conserved Domains (2) summary
    cd08539
    Location:61 → 138
    SAM_PNT-ESE-3-like; Sterile alpha motif (SAM)/Pointed domain of ESE-3 like ETS transcriptional regulators
    smart00413
    Location:228 → 315
    ETS; erythroblast transformation specific domain

  3. NM_001378041.1 → NP_001364970.1  ETS homologous factor isoform 2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4), as well as variants 2 and 5-10, encodes isoform 2.
    Source sequence(s)
    AC087783
    Consensus CDS
    CCDS7894.1
    UniProtKB/Swiss-Prot
    D3DR08, D3DR10, E9PSB2, Q9H509, Q9NZC4, Q9UKF9, Q9Y5V4, Q9Y5V5
    Conserved Domains (2) summary
    cd08539
    Location:39 → 116
    SAM_PNT-ESE-3-like; Sterile alpha motif (SAM)/Pointed domain of ESE-3 like ETS transcriptional regulators
    smart00413
    Location:206 → 293
    ETS; erythroblast transformation specific domain

  4. NM_001378042.1 → NP_001364971.1  ETS homologous factor isoform 2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5), as well as variants 2, 4, and 6-10, encodes isoform 2.
    Source sequence(s)
    AC087783
    Consensus CDS
    CCDS7894.1
    UniProtKB/Swiss-Prot
    D3DR08, D3DR10, E9PSB2, Q9H509, Q9NZC4, Q9UKF9, Q9Y5V4, Q9Y5V5
    Conserved Domains (2) summary
    cd08539
    Location:39 → 116
    SAM_PNT-ESE-3-like; Sterile alpha motif (SAM)/Pointed domain of ESE-3 like ETS transcriptional regulators
    smart00413
    Location:206 → 293
    ETS; erythroblast transformation specific domain

  5. NM_001378043.1 → NP_001364972.1  ETS homologous factor isoform 2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6), as well as variants 2, 4, 5, and 7-10, encodes isoform 2.
    Source sequence(s)
    AC087783
    Consensus CDS
    CCDS7894.1
    UniProtKB/Swiss-Prot
    D3DR08, D3DR10, E9PSB2, Q9H509, Q9NZC4, Q9UKF9, Q9Y5V4, Q9Y5V5
    Conserved Domains (2) summary
    cd08539
    Location:39 → 116
    SAM_PNT-ESE-3-like; Sterile alpha motif (SAM)/Pointed domain of ESE-3 like ETS transcriptional regulators
    smart00413
    Location:206 → 293
    ETS; erythroblast transformation specific domain

  6. NM_001378044.1 → NP_001364973.1  ETS homologous factor isoform 2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7), as well as variants 2, 4-6, and 8-10, encodes isoform 2.
    Source sequence(s)
    AC087783
    Consensus CDS
    CCDS7894.1
    UniProtKB/Swiss-Prot
    D3DR08, D3DR10, E9PSB2, Q9H509, Q9NZC4, Q9UKF9, Q9Y5V4, Q9Y5V5
    Related
    ENSP00000433508.1, ENST00000530286.5
    Conserved Domains (2) summary
    cd08539
    Location:39 → 116
    SAM_PNT-ESE-3-like; Sterile alpha motif (SAM)/Pointed domain of ESE-3 like ETS transcriptional regulators
    smart00413
    Location:206 → 293
    ETS; erythroblast transformation specific domain

  7. NM_001378045.1 → NP_001364974.1  ETS homologous factor isoform 2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9), as well as variants 2, 4-8, and 10, encodes isoform 2.
    Source sequence(s)
    AC087783
    Consensus CDS
    CCDS7894.1
    UniProtKB/Swiss-Prot
    D3DR08, D3DR10, E9PSB2, Q9H509, Q9NZC4, Q9UKF9, Q9Y5V4, Q9Y5V5
    Conserved Domains (2) summary
    cd08539
    Location:39 → 116
    SAM_PNT-ESE-3-like; Sterile alpha motif (SAM)/Pointed domain of ESE-3 like ETS transcriptional regulators
    smart00413
    Location:206 → 293
    ETS; erythroblast transformation specific domain

  8. NM_001378046.1 → NP_001364975.1  ETS homologous factor isoform 2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10), as well as variants 2 and 4-9, encodes isoform 2.
    Source sequence(s)
    AC087783
    Consensus CDS
    CCDS7894.1
    UniProtKB/Swiss-Prot
    D3DR08, D3DR10, E9PSB2, Q9H509, Q9NZC4, Q9UKF9, Q9Y5V4, Q9Y5V5
    Conserved Domains (2) summary
    cd08539
    Location:39 → 116
    SAM_PNT-ESE-3-like; Sterile alpha motif (SAM)/Pointed domain of ESE-3 like ETS transcriptional regulators
    smart00413
    Location:206 → 293
    ETS; erythroblast transformation specific domain

  9. NM_001378047.1 → NP_001364976.1  ETS homologous factor isoform 2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8), as well as variants 2, 4-7, 9, and 10, encodes isoform 2.
    Source sequence(s)
    AC087783
    Consensus CDS
    CCDS7894.1
    UniProtKB/Swiss-Prot
    D3DR08, D3DR10, E9PSB2, Q9H509, Q9NZC4, Q9UKF9, Q9Y5V4, Q9Y5V5
    Conserved Domains (2) summary
    cd08539
    Location:39 → 116
    SAM_PNT-ESE-3-like; Sterile alpha motif (SAM)/Pointed domain of ESE-3 like ETS transcriptional regulators
    smart00413
    Location:206 → 293
    ETS; erythroblast transformation specific domain

  10. NM_001378048.1 → NP_001364977.1  ETS homologous factor isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11), as well as variant 3, encodes isoform 3.
    Source sequence(s)
    AC087783
    Consensus CDS
    CCDS55753.1
    Conserved Domains (2) summary
    cd08539
    Location:39 → 116
    SAM_PNT-ESE-3-like; Sterile alpha motif (SAM)/Pointed domain of ESE-3 like ETS transcriptional regulators
    smart00413
    Location:183 → 270
    ETS; erythroblast transformation specific domain

  11. NM_001378049.1 → NP_001364978.1  ETS homologous factor isoform 4

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12), as well as variants 13 and 14, encodes isoform 4.
    Source sequence(s)
    AC087783
    Conserved Domains (2) summary
    cd08539
    Location:39 → 116
    SAM_PNT-ESE-3-like; Sterile alpha motif (SAM)/Pointed domain of ESE-3 like ETS transcriptional regulators
    smart00413
    Location:205 → 292
    ETS; erythroblast transformation specific domain

  12. NM_001378050.1 → NP_001364979.1  ETS homologous factor isoform 4

    Status: REVIEWED

    Description
    Transcript Variant: This variant (13), as well as variants 12 and 14, encodes isoform 4.
    Source sequence(s)
    AC087783
    Conserved Domains (2) summary
    cd08539
    Location:39 → 116
    SAM_PNT-ESE-3-like; Sterile alpha motif (SAM)/Pointed domain of ESE-3 like ETS transcriptional regulators
    smart00413
    Location:205 → 292
    ETS; erythroblast transformation specific domain

  13. NM_001378051.1 → NP_001364980.1  ETS homologous factor isoform 4

    Status: REVIEWED

    Description
    Transcript Variant: This variant (14), as well as variants 12 and 13, encodes isoform 4.
    Source sequence(s)
    AC087783
    Conserved Domains (2) summary
    cd08539
    Location:39 → 116
    SAM_PNT-ESE-3-like; Sterile alpha motif (SAM)/Pointed domain of ESE-3 like ETS transcriptional regulators
    smart00413
    Location:205 → 292
    ETS; erythroblast transformation specific domain

  14. NM_001378052.1 → NP_001364981.1  ETS homologous factor isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC087783
    Conserved Domains (2) summary
    cd08539
    Location:61 → 138
    SAM_PNT-ESE-3-like; Sterile alpha motif (SAM)/Pointed domain of ESE-3 like ETS transcriptional regulators
    smart00413
    Location:227 → 314
    ETS; erythroblast transformation specific domain

  15. NM_001378053.1 → NP_001364982.1  ETS homologous factor isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC087783
    Conserved Domains (2) summary
    cd08539
    Location:42 → 119
    SAM_PNT-ESE-3-like; Sterile alpha motif (SAM)/Pointed domain of ESE-3 like ETS transcriptional regulators
    smart00413
    Location:209 → 296
    ETS; erythroblast transformation specific domain

  16. NM_001378054.1 → NP_001364983.1  ETS homologous factor isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC087783
    Conserved Domains (2) summary
    cd08539
    Location:39 → 116
    SAM_PNT-ESE-3-like; Sterile alpha motif (SAM)/Pointed domain of ESE-3 like ETS transcriptional regulators
    smart00413
    Location:182 → 269
    ETS; erythroblast transformation specific domain

  17. NM_001378055.1 → NP_001364984.1  ETS homologous factor isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC087783
    Conserved Domains (2) summary
    cd08539
    Location:42 → 119
    SAM_PNT-ESE-3-like; Sterile alpha motif (SAM)/Pointed domain of ESE-3 like ETS transcriptional regulators
    smart00413
    Location:186 → 273
    ETS; erythroblast transformation specific domain

  18. NM_001378056.1 → NP_001364985.1  ETS homologous factor isoform 9

    Status: REVIEWED

    Source sequence(s)
    AC087783
    Conserved Domains (2) summary
    smart00413
    Location:119 → 206
    ETS; erythroblast transformation specific domain
    cl15755
    Location:1 → 29
    SAM_superfamily; SAM (Sterile alpha motif )

  19. NM_012153.6 → NP_036285.2  ETS homologous factor isoform 2

    See identical proteins and their annotated locations for NP_036285.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1. Variants 2 and 4-10 all encode the same isoform (2).
    Source sequence(s)
    AC087783
    Consensus CDS
    CCDS7894.1
    UniProtKB/Swiss-Prot
    D3DR08, D3DR10, E9PSB2, Q9H509, Q9NZC4, Q9UKF9, Q9Y5V4, Q9Y5V5
    Related
    ENSP00000257831.3, ENST00000257831.8
    Conserved Domains (2) summary
    cd08539
    Location:39 → 116
    SAM_PNT-ESE-3-like; Sterile alpha motif (SAM)/Pointed domain of ESE-3 like ETS transcriptional regulators
    smart00413
    Location:206 → 293
    ETS; erythroblast transformation specific domain

RNA

  1. NR_165390.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC087783

  2. NR_165391.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC087783

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    34621093..34663288
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047426759.1 → XP_047282715.1  ETS homologous factor isoform X1

    UniProtKB/Swiss-Prot
    D3DR08, D3DR10, E9PSB2, Q9H509, Q9NZC4, Q9UKF9, Q9Y5V4, Q9Y5V5

  2. XM_047426758.1 → XP_047282714.1  ETS homologous factor isoform X1

    UniProtKB/Swiss-Prot
    D3DR08, D3DR10, E9PSB2, Q9H509, Q9NZC4, Q9UKF9, Q9Y5V4, Q9Y5V5
    Related
    ENSP00000435837.1, ENST00000533754.5

  3. XM_047426755.1 → XP_047282711.1  ETS homologous factor isoform X1

    UniProtKB/Swiss-Prot
    D3DR08, D3DR10, E9PSB2, Q9H509, Q9NZC4, Q9UKF9, Q9Y5V4, Q9Y5V5

  4. XM_047426756.1 → XP_047282712.1  ETS homologous factor isoform X1

    UniProtKB/Swiss-Prot
    D3DR08, D3DR10, E9PSB2, Q9H509, Q9NZC4, Q9UKF9, Q9Y5V4, Q9Y5V5

  5. XM_047426761.1 → XP_047282717.1  ETS homologous factor isoform X2

  6. XM_047426762.1 → XP_047282718.1  ETS homologous factor isoform X4

  7. XM_047426754.1 → XP_047282710.1  ETS homologous factor isoform X1

    UniProtKB/Swiss-Prot
    D3DR08, D3DR10, E9PSB2, Q9H509, Q9NZC4, Q9UKF9, Q9Y5V4, Q9Y5V5

  8. XM_047426760.1 → XP_047282716.1  ETS homologous factor isoform X2

  9. XM_047426753.1 → XP_047282709.1  ETS homologous factor isoform X1

    UniProtKB/Swiss-Prot
    D3DR08, D3DR10, E9PSB2, Q9H509, Q9NZC4, Q9UKF9, Q9Y5V4, Q9Y5V5

  10. XM_047426757.1 → XP_047282713.1  ETS homologous factor isoform X1

    UniProtKB/Swiss-Prot
    D3DR08, D3DR10, E9PSB2, Q9H509, Q9NZC4, Q9UKF9, Q9Y5V4, Q9Y5V5

  11. XM_005252861.2 → XP_005252918.1  ETS homologous factor isoform X3

    Conserved Domains (2) summary
    cd08539
    Location:61 → 138
    SAM_PNT-ESE-3-like; Sterile alpha motif (SAM)/Pointed domain of ESE-3 like ETS transcriptional regulators
    smart00413
    Location:205 → 292
    ETS; erythroblast transformation specific domain

  12. XM_024448434.2 → XP_024304202.1  ETS homologous factor isoform X1

    UniProtKB/Swiss-Prot
    D3DR08, D3DR10, E9PSB2, Q9H509, Q9NZC4, Q9UKF9, Q9Y5V4, Q9Y5V5
    Conserved Domains (2) summary
    cd08539
    Location:39 → 116
    SAM_PNT-ESE-3-like; Sterile alpha motif (SAM)/Pointed domain of ESE-3 like ETS transcriptional regulators
    smart00413
    Location:206 → 293
    ETS; erythroblast transformation specific domain

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    34757923..34800105
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054368403.1 → XP_054224378.1  ETS homologous factor isoform X1

    UniProtKB/Swiss-Prot
    D3DR08, D3DR10, E9PSB2, Q9H509, Q9NZC4, Q9UKF9, Q9Y5V4, Q9Y5V5

  2. XM_054368402.1 → XP_054224377.1  ETS homologous factor isoform X1

    UniProtKB/Swiss-Prot
    D3DR08, D3DR10, E9PSB2, Q9H509, Q9NZC4, Q9UKF9, Q9Y5V4, Q9Y5V5

  3. XM_054368399.1 → XP_054224374.1  ETS homologous factor isoform X1

    UniProtKB/Swiss-Prot
    D3DR08, D3DR10, E9PSB2, Q9H509, Q9NZC4, Q9UKF9, Q9Y5V4, Q9Y5V5

  4. XM_054368400.1 → XP_054224375.1  ETS homologous factor isoform X1

    UniProtKB/Swiss-Prot
    D3DR08, D3DR10, E9PSB2, Q9H509, Q9NZC4, Q9UKF9, Q9Y5V4, Q9Y5V5

  5. XM_054368406.1 → XP_054224381.1  ETS homologous factor isoform X2

  6. XM_054368408.1 → XP_054224383.1  ETS homologous factor isoform X4

  7. XM_054368398.1 → XP_054224373.1  ETS homologous factor isoform X1

    UniProtKB/Swiss-Prot
    D3DR08, D3DR10, E9PSB2, Q9H509, Q9NZC4, Q9UKF9, Q9Y5V4, Q9Y5V5

  8. XM_054368405.1 → XP_054224380.1  ETS homologous factor isoform X2

  9. XM_054368397.1 → XP_054224372.1  ETS homologous factor isoform X1

    UniProtKB/Swiss-Prot
    D3DR08, D3DR10, E9PSB2, Q9H509, Q9NZC4, Q9UKF9, Q9Y5V4, Q9Y5V5

  10. XM_054368401.1 → XP_054224376.1  ETS homologous factor isoform X1

    UniProtKB/Swiss-Prot
    D3DR08, D3DR10, E9PSB2, Q9H509, Q9NZC4, Q9UKF9, Q9Y5V4, Q9Y5V5

  11. XM_054368407.1 → XP_054224382.1  ETS homologous factor isoform X3

  12. XM_054368404.1 → XP_054224379.1  ETS homologous factor isoform X1

    UniProtKB/Swiss-Prot
    D3DR08, D3DR10, E9PSB2, Q9H509, Q9NZC4, Q9UKF9, Q9Y5V4, Q9Y5V5
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9NZC4.1 GenPept UniProtKB/Swiss-Prot:Q9NZC4

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