Or5k17 olfactory receptor family 5 subfamily K member 17 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Or5k17provided by MGI
Official Full Name: olfactory receptor family 5 subfamily K member 17provided by MGI
Primary source: MGI:MGI:3030015
See related: Ensembl:ENSMUSG00000090951 AllianceGenome:MGI:3030015
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Olfr181; MOR184-4
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Expression: Low expression observed in reference dataset See more
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Genomic context

Location:: 16 C1.2; 16 34.83 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	16	NC_000082.7 (58745920..58749007, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	16	NC_000082.6 (58925557..58928644, complement)

Chromosome 16 - NC_000082.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

NoName (e-PCR)
- UniSTS:489489

NoName (e-PCR)
- UniSTS:495659

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables odorant binding	IBA Inferred from Biological aspect of Ancestor more info
enables olfactory receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables olfactory receptor activity	ISA Inferred from Sequence Alignment more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	ISA Inferred from Sequence Alignment more info	PubMed
acts_upstream_of_or_within response to stimulus	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within sensory perception of smell	ISA Inferred from Sequence Alignment more info	PubMed
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	ISA Inferred from Sequence Alignment more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: olfactory receptor 5K17

Names: GA_x54KRFPKG5P-55145984-55145034; olfactory receptor 181; olfactory receptor 184-4; olfactory receptor MOR184-4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_146999.2 → NP_667210.2 olfactory receptor 5K17

See identical proteins and their annotated locations for NP_667210.2

Status: VALIDATED

Source sequence(s)

AC154545

Consensus CDS

CCDS28240.1

UniProtKB/Swiss-Prot

E9QKY8, Q05A60, Q7TS47, Q8VGQ7

UniProtKB/TrEMBL

A2RRZ5

Related

ENSMUSP00000074825.4, ENSMUST00000075361.5

Conserved Domains (2) summary

cd14964
Location:26 → 52

7tm_GPCRs; TM helix 1 [structural motif]

cl28897
Location:25 → 300

7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily