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Or10b1 olfactory receptor family 10 subfamily B member 1 [ Mus musculus (house mouse) ]

Gene ID: 258224, updated on 8-Feb-2024

Summary

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Official Symbol
Or10b1provided by MGI
Official Full Name
olfactory receptor family 10 subfamily B member 1provided by MGI
Primary source
MGI:MGI:3031192
See related
Ensembl:ENSMUSG00000107822 AllianceGenome:MGI:3031192
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MOR267-9; Olfr1358
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Expression
Biased expression in testis adult (RPKM 1.2), ovary adult (RPKM 1.2) and 2 other tissues See more
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Genomic context

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Location:
10 C1; 10 39.72 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (78334017..78357117)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (78498183..78521283)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene pyridoxal (pyridoxine, vitamin B6) kinase Neighboring gene microRNA 6908 Neighboring gene predicted gene, 30232 Neighboring gene predicted gene, 47944 Neighboring gene protein tyrosine phosphatase 4a1 pseudogene Neighboring gene vomeronasal 2, receptor, pseudogene 92

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
  2. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
  3. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article
  4. A unified nomenclature for vertebrate olfactory receptors. Olender T, et al. BMC Evol Biol, 2020 Apr 15. PMID 32295537, Free PMC Article
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables odorant binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
Inferred from Sequence Alignment
more info
 PubMed 
acts_upstream_of_or_within sensory perception of smell ISA
Inferred from Sequence Alignment
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane ISA
Inferred from Sequence Alignment
more info
 PubMed 

General protein information

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Preferred Names
olfactory receptor 1358
Names
GA_x6K02T2QGN0-3289955-3289014
olfactory receptor MOR267-9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001370810.1 → NP_001357739.1  olfactory receptor 1358

    Status: VALIDATED

    Source sequence(s)
    AC025913
    Consensus CDS
    CCDS88045.1
    UniProtKB/TrEMBL
    A0A2I3BRV4, Q7TQU6
    Related
    ENSMUSP00000154751.2, ENSMUST00000204477.5
    Conserved Domains (1) summary
    cd15225
    Location:30 → 306
    7tmA_OR10A-like; olfactory receptor subfamily 10A and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    78334017..78357117
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030245092.1 → XP_030100952.1  olfactory receptor 1358 isoform X1

    UniProtKB/TrEMBL
    Q7TQU6
    Conserved Domains (1) summary
    cd15225
    Location:42 → 318
    7tmA_OR10A-like; olfactory receptor subfamily 10A and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
Nucleotide Protein
Heading Accession and Version

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