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Or52ab2 olfactory receptor family 52 subfamily AB member 2 [ Mus musculus (house mouse) ]

Gene ID: 258135, updated on 8-Feb-2024

Summary

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Official Symbol
Or52ab2provided by MGI
Official Full Name
olfactory receptor family 52 subfamily AB member 2provided by MGI
Primary source
MGI:MGI:3030431
See related
Ensembl:ENSMUSG00000073952 AllianceGenome:MGI:3030431
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MOR23-2; Olfr597; GA_x5J8B7TU1BB-380-666
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
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Genomic context

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Location:
7 E3; 7 54.85 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (102969620..102970567)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (103320413..103321360)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 17-like D Neighboring gene STARR-seq mESC enhancer starr_19720 Neighboring gene olfactory receptor family 52 subfamily E member 19 Neighboring gene olfactory receptor family 52 subfamily AB member 7 Neighboring gene olfactory receptor family 52 subfamily AB member 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
  2. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
  3. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article
  4. A unified nomenclature for vertebrate olfactory receptors. Olender T, et al. BMC Evol Biol, 2020 Apr 15. PMID 32295537, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
Inferred from Sequence Alignment
more info
 PubMed 
acts_upstream_of_or_within sensory perception of smell ISA
Inferred from Sequence Alignment
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane ISA
Inferred from Sequence Alignment
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
olfactory receptor 597
Names
GA_x6K02T2PBJ9-6029614-6030561
olfactory receptor GA_x5J8B7TU1BB-380-666
olfactory receptor MOR23-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001011845.2 → NP_001011845.2  olfactory receptor 597

    Status: VALIDATED

    Source sequence(s)
    AC108410
    Consensus CDS
    CCDS52336.1
    UniProtKB/TrEMBL
    L7N224, Q7TRR3
    Related
    ENSMUSP00000095804.3, ENSMUST00000098203.4
    Conserved Domains (2) summary
    pfam00001
    Location:55 → 293
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:54 → 308
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    102969620..102970567
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_001630.1: Suppressed sequence

    Description
    NG_001630.1: This RefSeq was permanently suppressed because it is now thought that this gene encodes a protein.

  2. NG_002022.1: Suppressed sequence

    Description
    NG_002022.1: This RefSeq was permanently suppressed because it is now thought that this gene encodes a protein.
Nucleotide Protein
Heading Accession and Version

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