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Or7a39 olfactory receptor family 7 subfamily A member 39 [ Mus musculus (house mouse) ]

Gene ID: 257734, updated on 8-Feb-2024

Summary

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Official Symbol
Or7a39provided by MGI
Official Full Name
olfactory receptor family 7 subfamily A member 39provided by MGI
Primary source
MGI:MGI:3031189
See related
Ensembl:ENSMUSG00000062873 AllianceGenome:MGI:3031189
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MOR139-6; Olfr1355; GA_x5J8B7W4DUT-12263-11330
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
10 C1; 10 39.72 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (78711383..78715940)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (78875549..78880106)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene tektin like 1 Neighboring gene solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 Neighboring gene STARR-seq mESC enhancer starr_27235 Neighboring gene olfactory receptor family 7 subfamily C member 70 Neighboring gene STARR-seq mESC enhancer starr_27236 Neighboring gene olfactory receptor family 7 subfamily A member 38 Neighboring gene STARR-seq mESC enhancer starr_27237 Neighboring gene olfactory receptor family 7 subfamily A member 42

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates. Rouquier S, et al. Proc Natl Acad Sci U S A, 2000 Mar 14. PMID 10706615, Free PMC Article
  2. Odorant and vomeronasal receptor genes in two mouse genome assemblies. Zhang X, et al. Genomics, 2004 May. PMID 15081110
  3. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
  4. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article
  5. A unified nomenclature for vertebrate olfactory receptors. Olender T, et al. BMC Evol Biol, 2020 Apr 15. PMID 32295537, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
Inferred from Sequence Alignment
more info
 PubMed 
acts_upstream_of_or_within sensory perception of smell ISA
Inferred from Sequence Alignment
more info
 PubMed 
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane ISA
Inferred from Sequence Alignment
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
olfactory receptor 1355
Names
GA_x6K02T2QGN0-2932609-2931677
M65 odorant receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_207571.2 → NP_997454.1  olfactory receptor 1355

    See identical proteins and their annotated locations for NP_997454.1

    Status: VALIDATED

    Source sequence(s)
    AC158798, CB173142
    Consensus CDS
    CCDS48615.1
    UniProtKB/TrEMBL
    Q7TQU9, Q9JHW3
    Related
    ENSMUSP00000077517.7, ENSMUST00000078414.8
    Conserved Domains (2) summary
    pfam00001
    Location:42 → 291
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:32 → 309
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    78711383..78715940
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_001622.1: Suppressed sequence

    Description
    NG_001622.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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