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OOSP1 oocyte secreted protein 1 [ Homo sapiens (human) ]

Gene ID: 255649, updated on 5-Mar-2024

Summary

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Official Symbol
OOSP1provided by HGNC
Official Full Name
oocyte secreted protein 1provided by HGNC
Primary source
HGNC:HGNC:49233
See related
Ensembl:ENSG00000284873 AllianceGenome:HGNC:49233
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
mouse all
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Genomic context

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Location:
11q12.1
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (59938432..59957480)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (59889734..59908777)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (59705905..59724953)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene oocyte secreted protein family member 3 Neighboring gene steroid 5 alpha-reductase 3 pseudogene 1 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:59688942-59689102 Neighboring gene Sharpr-MPRA regulatory region 15631 Neighboring gene oocyte secreted protein family member 4A Neighboring gene oocyte secreted protein family member 4B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Oosp1 encodes a novel mouse oocyte-secreted protein. Yan C, et al. Genesis, 2001 Nov. PMID 11747200
  2. Human chromosome 11 DNA sequence and analysis including novel gene identification. Taylor TD, et al. Nature, 2006 Mar 23. PMID 16554811

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
putative oocyte-secreted protein 1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001395276.1 → NP_001382205.1  putative oocyte-secreted protein 1 homolog precursor

    Status: VALIDATED

    Source sequence(s)
    AP000790
    Consensus CDS
    CCDS91478.1
    UniProtKB/TrEMBL
    A0A2R8Y634, A0A2R8YCH4
    Related
    ENSP00000493578.1, ENST00000646685.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    59938432..59957480
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047426711.1 → XP_047282667.1  putative oocyte-secreted protein 1 homolog isoform X1

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_019805498.1 Reference GRCh38.p14 PATCHES

    Range
    26065..47135
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054332429.1 → XP_054188404.1  putative oocyte-secreted protein 1 homolog isoform X2

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    59889734..59908777
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054368311.1 → XP_054224286.1  putative oocyte-secreted protein 1 homolog isoform X1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_130719.1: Suppressed sequence

    Description
    NR_130719.1: This RefSeq was removed because it is now thought that this gene does encode a protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A8MZH6.1 GenPept UniProtKB/Swiss-Prot:A8MZH6

Gene LinkOut

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