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REXO1L1P REXO1 like 1, pseudogene [ Homo sapiens (human) ]

Gene ID: 254958, updated on 23-Nov-2023

Summary

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Official Symbol
REXO1L1Pprovided by HGNC
Official Full Name
REXO1 like 1, pseudogeneprovided by HGNC
Primary source
HGNC:HGNC:24660
See related
AllianceGenome:HGNC:24660
Gene type
pseudo
RefSeq status
INFERRED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GOR; REXO1L1
Summary
Predicted to enable exonuclease activity. Predicted to be involved in nucleic acid phosphodiester bond hydrolysis. Predicted to be located in cytoplasm. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
8q21.2
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (85661256..85662410, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (86204232..86205386, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (86573485..86574639, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene REXO1 like 8, pseudogene Neighboring gene OCT4 hESC enhancer GRCh37_chr8:86560715-86561216 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:86567267-86568134 Neighboring gene REXO1 like 3, pseudogene Neighboring gene OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:86573707-86574476 Neighboring gene REXO1 like 12, pseudogene Neighboring gene putative exonuclease GOR Neighboring gene REXO1 like 11, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Serum immunoglobulin G antibodies to the GOR autoepitope are present in patients with occult hepatitis C virus (HCV) infection despite lack of HCV-specific antibodies. Quiroga JA, et al. Clin Vaccine Immunol, 2007 Oct. PMID 17699833, Free PMC Article
  2. The GOR gene product cannot cross-react with hepatitis C virus in humans. Koike R, et al. Clin Exp Immunol, 2001 Jun. PMID 11472404, Free PMC Article
  3. The GOR47-1 sequence in human DNA encoding for a potential autoantigen in connection with hepatitis C--a sequence not only reserved for humans. Dennin RH, et al. Z Gastroenterol, 1998 Oct. PMID 9846365
  4. Non-A, non-B hepatitis specific antibodies directed at host-derived epitope: implication for an autoimmune process. Mishiro S, et al. Lancet, 1990 Dec 8. PMID 1701012
  5. Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei. Fasci D, et al. Mol Cell Proteomics, 2018 Oct. PMID 30021884, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Sera from 20% of patients with occult hepatitis C infection react with the GOR autoepitope in enzyme immumoassays, although this frequency is lower than the GOR reactivity of patients with chronic hepatitis C.
    Title: Serum immunoglobulin G antibodies to the GOR autoepitope are present in patients with occult hepatitis C virus (HCV) infection despite lack of HCV-specific antibodies.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Other Names

  • REX1, RNA exonuclease 1 homolog-like 1, pseudogene
  • antigen GOR homolog
  • exonuclease GOR

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables exonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_053157.1 

    Range
    101..1255
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    85661256..85662410 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    86204232..86205386 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_172239.4: Suppressed sequence

    Description
    NM_172239.4: This RefSeq was permanently suppressed because it is now thought that this gene does not encode a protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8IX06.2 GenPept UniProtKB/Swiss-Prot:Q8IX06

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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