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Obox6 oocyte specific homeobox 6 [ Mus musculus (house mouse) ]

Gene ID: 252830, updated on 11-Apr-2024

Summary

Official Symbol
Obox6provided by MGI
Official Full Name
oocyte specific homeobox 6provided by MGI
Primary source
MGI:MGI:2149036
See related
Ensembl:ENSMUSG00000041583 AllianceGenome:MGI:2149036
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D17Ertd599e
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is expressed in bladder; early conceptus; gonad; and thymus. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

Location:
7 A2; 7 8.59 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (15567175..15573604, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (15833250..15839679, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene oocyte specific homeobox 4, pseudogene 34 Neighboring gene oocyte specific homeobox 5 Neighboring gene STARR-seq mESC enhancer starr_18112 Neighboring gene STARR-seq mESC enhancer starr_18113 Neighboring gene cone-rod homeobox Neighboring gene STARR-seq mESC enhancer starr_18114 Neighboring gene STARR-seq mESC enhancer starr_18115 Neighboring gene cone-rod homeobox, opposite strand

Genomic regions, transcripts, and products

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
oocyte-specific homeobox protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145710.2NP_663756.2  oocyte-specific homeobox protein 6

    See identical proteins and their annotated locations for NP_663756.2

    Status: VALIDATED

    Source sequence(s)
    BG069935, BY731792, CN712286, CN721150
    Consensus CDS
    CCDS20839.2
    UniProtKB/Swiss-Prot
    A0PK85, G3X9U1, Q8VHG3
    Related
    ENSMUSP00000104153.4, ENSMUST00000108513.5
    Conserved Domains (2) summary
    COG5576
    Location:86204
    COG5576; Homeodomain-containing transcription factor [Transcription]
    cd00086
    Location:146204
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    15567175..15573604 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)