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CG30083 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 246444, updated on 4-Apr-2024

Summary

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Official Symbol
CG30083provided by FlyBase
Primary source
FLYBASE:FBgn0050083
Locus tag
Dmel_CG30083
See related
AllianceGenome:FB:FBgn0050083
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG30083; SP217
Summary
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
52C2-52C2; 2-75 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (15711597..15712644, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (11599102..11600149, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Z band alternatively spliced PDZ-motif protein 52 Neighboring gene tungus

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Whole-genome expression plasticity across tropical and temperate Drosophila melanogaster populations from Eastern Australia. Levine MT, et al. Mol Biol Evol, 2011 Jan. PMID 20671040, Free PMC Article
  2. Natural variation in the regulation of neurodevelopmental genes modifies flight performance in Drosophila. Spierer AN, et al. PLoS Genet, 2021 Mar. PMID 33735180, Free PMC Article
  3. Genomic mapping of Suppressor of Hairy-wing binding sites in Drosophila. Adryan B, et al. Genome Biol, 2007. PMID 17705839, Free PMC Article
  4. Building a platform for predicting functions of serine protease-related proteins in Drosophila melanogaster and other insects. Cao X, et al. Insect Biochem Mol Biol, 2018 Dec. PMID 30367934, Free PMC Article
  5. A Superfamily-wide Activity Atlas of Serine Hydrolases in Drosophila melanogaster. Kumar K, et al. Biochemistry, 2021 Apr 27. PMID 33827210, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables serine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type endopeptidase activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG30083-PB
NP_725492.3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    15711597..15712644 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_166116.3 → NP_725492.3  uncharacterized protein Dmel_CG30083 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_725492.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1ZA44, A8WHC4, B3DNE0
    Conserved Domains (2) summary
    smart00020
    Location:33 → 255
    Tryp_SPc; Trypsin-like serine protease
    cd00190
    Location:34 → 255
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1ZA44 A1ZA44

Gene LinkOut

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Other Literature Sources
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