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Tceanc transcription elongation factor A (SII) N-terminal and central domain containing [ Mus musculus (house mouse) ]

Gene ID: 245695, updated on 11-Apr-2024

Summary

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Official Symbol
Tceancprovided by MGI
Official Full Name
transcription elongation factor A (SII) N-terminal and central domain containingprovided by MGI
Primary source
MGI:MGI:2685236
See related
Ensembl:ENSMUSG00000051224 AllianceGenome:MGI:2685236
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm390; A630018P17Rik
Summary
Predicted to be involved in transcription, DNA-templated. Predicted to be active in nucleus. Orthologous to human TCEANC (transcription elongation factor A N-terminal and central domain containing). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 1.6), CNS E11.5 (RPKM 1.3) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
X F5; X 77.59 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (165282806..165301594, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (166499810..166518603, complement)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 154, member A pseudogene Neighboring gene predicted gene 15223 Neighboring gene STARR-seq mESC enhancer starr_48253 Neighboring gene EGF-like-domain, multiple 6 Neighboring gene STARR-seq mESC enhancer starr_48256 Neighboring gene STARR-seq mESC enhancer starr_48259 Neighboring gene CapStarr-seq enhancer MGSCv37_chrX:163099414-163099597 Neighboring gene predicted gene 1720

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network. Shalom-Barak T, et al. Dev Biol, 2012 Dec 1. PMID 22967998, Free PMC Article
  2. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC93029

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
transcription elongation factor A N-terminal and central domain-containing protein
Names
TFIIS central domain-containing protein 1
TFS2-M domain-containing protein 1
novel transcription factor S-II (TFIIS), central domain containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007577.2 → NP_001007578.2  transcription elongation factor A N-terminal and central domain-containing protein

    See identical proteins and their annotated locations for NP_001007578.2

    Status: VALIDATED

    Source sequence(s)
    AK140929, AL672174, BU611745, CO044580
    Consensus CDS
    CCDS53249.1
    UniProtKB/Swiss-Prot
    Q3US16, Q6NXL9, Q8BY92
    Related
    ENSMUSP00000107806.2, ENSMUST00000112188.8
    Conserved Domains (2) summary
    pfam07500
    Location:181 → 290
    TFIIS_M; Transcription factor S-II (TFIIS), central domain
    cl02609
    Location:298 → 351
    Zn-ribbon; C-terminal zinc ribbon domain of RNA polymerase intrinsic transcript cleavage subunit

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    165282806..165301594 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011247827.4 → XP_011246129.1  transcription elongation factor A N-terminal and central domain-containing protein isoform X1

    See identical proteins and their annotated locations for XP_011246129.1

    UniProtKB/Swiss-Prot
    Q3US16, Q6NXL9, Q8BY92
    Related
    ENSMUSP00000136691.2, ENSMUST00000180322.2
    Conserved Domains (2) summary
    pfam07500
    Location:181 → 290
    TFIIS_M; Transcription factor S-II (TFIIS), central domain
    cl02609
    Location:298 → 351
    Zn-ribbon; C-terminal zinc ribbon domain of RNA polymerase intrinsic transcript cleavage subunit

  2. XM_006528863.5 → XP_006528926.1  transcription elongation factor A N-terminal and central domain-containing protein isoform X1

    See identical proteins and their annotated locations for XP_006528926.1

    UniProtKB/Swiss-Prot
    Q3US16, Q6NXL9, Q8BY92
    Conserved Domains (2) summary
    pfam07500
    Location:181 → 290
    TFIIS_M; Transcription factor S-II (TFIIS), central domain
    cl02609
    Location:298 → 351
    Zn-ribbon; C-terminal zinc ribbon domain of RNA polymerase intrinsic transcript cleavage subunit
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3US16.1 GenPept UniProtKB/Swiss-Prot:Q3US16

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