U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Nxpe4 neurexophilin and PC-esterase domain family, member 4 [ Mus musculus (house mouse) ]

Gene ID: 244853, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
Nxpe4provided by MGI
Official Full Name
neurexophilin and PC-esterase domain family, member 4provided by MGI
Primary source
MGI:MGI:1924792
See related
Ensembl:ENSMUSG00000044229 AllianceGenome:MGI:1924792
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fam55d; C130036J11; D930028F11Rik
Summary
Predicted to be located in extracellular region. Orthologous to human NXPE4 (neurexophilin and PC-esterase domain family member 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in liver E14 (RPKM 3.1), liver E14.5 (RPKM 3.0) and 24 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
9 A5.3; 9 26.39 cM
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (48073302..48311325)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (48162004..48400025)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32016 Neighboring gene STARR-seq mESC enhancer starr_24057 Neighboring gene STARR-seq mESC enhancer starr_24058 Neighboring gene predicted gene, 40518 Neighboring gene STARR-positive B cell enhancer mm9_chr9:48025608-48025909 Neighboring gene predicted gene, 57543 Neighboring gene predicted gene, 51672 Neighboring gene STARR-seq mESC enhancer starr_24065 Neighboring gene neurexophilin and PC-esterase domain family, member 2 Neighboring gene neurexophilin and PC-esterase domain family, member 1, pseudogene Neighboring gene predicted gene, 32131 Neighboring gene NHP2 non-histone chromosome protein 2-like 1 pseudogene

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The genomic determinants of alcohol preference in mice. Tabakoff B, et al. Mamm Genome, 2008 May. PMID 18563486, Free PMC Article
  2. Identification of candidate genes in the type 2 diabetes modifier locus using expression QTL. Yaguchi H, et al. Genomics, 2005 May. PMID 15820311
  3. Candidate genes and their regulatory elements: alcohol preference and tolerance. Saba L, et al. Mamm Genome, 2006 Jun. PMID 16783646
  4. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
NXPE family member 4
Names
family with sequence similarity 55, member D
protein FAM55D

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172921.3 → NP_766509.2  NXPE family member 4

    See identical proteins and their annotated locations for NP_766509.2

    Status: VALIDATED

    Source sequence(s)
    AC154373, AC160992
    Consensus CDS
    CCDS23152.1
    UniProtKB/Swiss-Prot
    Q0VGS9, Q52KP5, Q8BKY4
    UniProtKB/TrEMBL
    Q3UWC0
    Related
    ENSMUSP00000091375.5, ENSMUST00000093853.5
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    48073302..48311325
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036154984.1 → XP_036010877.1  NXPE family member 4 isoform X1

    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  2. XM_030244373.1 → XP_030100233.1  NXPE family member 4 isoform X3

    UniProtKB/Swiss-Prot
    Q0VGS9, Q52KP5, Q8BKY4
    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  3. XM_036154989.1 → XP_036010882.1  NXPE family member 4 isoform X1

    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  4. XM_017313377.2 → XP_017168866.1  NXPE family member 4 isoform X3

    UniProtKB/Swiss-Prot
    Q0VGS9, Q52KP5, Q8BKY4
    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  5. XM_036154996.1 → XP_036010889.1  NXPE family member 4 isoform X1

    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  6. XM_036154986.1 → XP_036010879.1  NXPE family member 4 isoform X1

    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  7. XM_017313375.3 → XP_017168864.1  NXPE family member 4 isoform X3

    UniProtKB/Swiss-Prot
    Q0VGS9, Q52KP5, Q8BKY4
    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  8. XM_036154995.1 → XP_036010888.1  NXPE family member 4 isoform X1

    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  9. XM_030244370.2 → XP_030100230.1  NXPE family member 4 isoform X3

    UniProtKB/Swiss-Prot
    Q0VGS9, Q52KP5, Q8BKY4
    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  10. XM_036155001.1 → XP_036010894.1  NXPE family member 4 isoform X2

    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  11. XM_030244368.1 → XP_030100228.1  NXPE family member 4 isoform X3

    UniProtKB/Swiss-Prot
    Q0VGS9, Q52KP5, Q8BKY4
    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  12. XM_030244367.1 → XP_030100227.1  NXPE family member 4 isoform X3

    UniProtKB/Swiss-Prot
    Q0VGS9, Q52KP5, Q8BKY4
    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  13. XM_036154991.1 → XP_036010884.1  NXPE family member 4 isoform X1

    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  14. XM_017313379.2 → XP_017168868.1  NXPE family member 4 isoform X3

    UniProtKB/Swiss-Prot
    Q0VGS9, Q52KP5, Q8BKY4
    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  15. XM_036154983.1 → XP_036010876.1  NXPE family member 4 isoform X1

    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  16. XM_011242528.3 → XP_011240830.1  NXPE family member 4 isoform X4

    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  17. XM_036154994.1 → XP_036010887.1  NXPE family member 4 isoform X1

    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  18. XM_030244369.1 → XP_030100229.1  NXPE family member 4 isoform X3

    UniProtKB/Swiss-Prot
    Q0VGS9, Q52KP5, Q8BKY4
    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  19. XM_036154997.1 → XP_036010890.1  NXPE family member 4 isoform X1

    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  20. XM_030244366.1 → XP_030100226.1  NXPE family member 4 isoform X3

    UniProtKB/Swiss-Prot
    Q0VGS9, Q52KP5, Q8BKY4
    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  21. XM_036154987.1 → XP_036010880.1  NXPE family member 4 isoform X1

    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  22. XM_036154985.1 → XP_036010878.1  NXPE family member 4 isoform X1

    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  23. XM_006510325.2 → XP_006510388.1  NXPE family member 4 isoform X3

    See identical proteins and their annotated locations for XP_006510388.1

    UniProtKB/Swiss-Prot
    Q0VGS9, Q52KP5, Q8BKY4
    UniProtKB/TrEMBL
    Q3UWC0
    Related
    ENSMUSP00000149741.2, ENSMUST00000215780.2
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  24. XM_030244376.2 → XP_030100236.1  NXPE family member 4 isoform X4

    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  25. XM_030244371.1 → XP_030100231.1  NXPE family member 4 isoform X3

    UniProtKB/Swiss-Prot
    Q0VGS9, Q52KP5, Q8BKY4
    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  26. XM_036154998.1 → XP_036010891.1  NXPE family member 4 isoform X1

    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  27. XM_017313384.1 → XP_017168873.1  NXPE family member 4 isoform X3

    UniProtKB/Swiss-Prot
    Q0VGS9, Q52KP5, Q8BKY4
    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  28. XM_036154988.1 → XP_036010881.1  NXPE family member 4 isoform X1

    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  29. XM_036154993.1 → XP_036010886.1  NXPE family member 4 isoform X1

    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  30. XM_036154999.1 → XP_036010892.1  NXPE family member 4 isoform X1

    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  31. XM_030244374.1 → XP_030100234.1  NXPE family member 4 isoform X3

    UniProtKB/Swiss-Prot
    Q0VGS9, Q52KP5, Q8BKY4
    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  32. XM_036154990.1 → XP_036010883.1  NXPE family member 4 isoform X1

    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  33. XM_017313378.1 → XP_017168867.1  NXPE family member 4 isoform X3

    UniProtKB/Swiss-Prot
    Q0VGS9, Q52KP5, Q8BKY4
    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  34. XM_030244377.2 → XP_030100237.1  NXPE family member 4 isoform X4

    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  35. XM_030244375.1 → XP_030100235.1  NXPE family member 4 isoform X3

    UniProtKB/Swiss-Prot
    Q0VGS9, Q52KP5, Q8BKY4
    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  36. XM_036155000.1 → XP_036010893.1  NXPE family member 4 isoform X1

    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin

  37. XM_036154992.1 → XP_036010885.1  NXPE family member 4 isoform X1

    UniProtKB/TrEMBL
    Q3UWC0
    Conserved Domains (1) summary
    pfam06312
    Location:129 → 255
    Neurexophilin
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q52KP5.1 GenPept UniProtKB/Swiss-Prot:Q52KP5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous