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Tnfrsf26 tumor necrosis factor receptor superfamily, member 26 [ Mus musculus (house mouse) ]

Gene ID: 244237, updated on 8-Feb-2024

Summary

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Official Symbol
Tnfrsf26provided by MGI
Official Full Name
tumor necrosis factor receptor superfamily, member 26provided by MGI
Primary source
MGI:MGI:2651928
See related
Ensembl:ENSMUSG00000045362 AllianceGenome:MGI:2651928
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tnfrh3; Tnfrsf24
Summary
Predicted to enable identical protein binding activity and protease binding activity. Predicted to be involved in TRAIL-activated apoptotic signaling pathway and positive regulation of apoptotic process. Predicted to be located in Golgi apparatus; cytosol; and membrane raft. Predicted to be active in cell surface and plasma membrane. Is expressed in several structures, including heart; hemolymphoid system gland; liver; lung; and placenta. Human ortholog(s) of this gene implicated in carcinoma (multiple); cervical cancer; hematologic cancer (multiple); and urinary bladder cancer. Orthologous to human TNFRSF10A (TNF receptor superfamily member 10a) and TNFRSF10C (TNF receptor superfamily member 10c). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in thymus adult (RPKM 2.0), spleen adult (RPKM 1.3) and 14 other tissues See more
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Genomic context

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See Tnfrsf26 in Genome Data Viewer
Location:
7 F5; 7 88.26 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (143161422..143181690, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (143607685..143627845, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene cysteinyl-tRNA synthetase 1 Neighboring gene STARR-positive B cell enhancer ABC_E1098 Neighboring gene predicted gene 15580 Neighboring gene predicted gene 15579 Neighboring gene RIKEN cDNA E230032D23 gene Neighboring gene STARR-positive B cell enhancer ABC_E6618 Neighboring gene STARR-seq mESC enhancer starr_20534 Neighboring gene tumor necrosis factor receptor superfamily, member 22 Neighboring gene tumor necrosis factor receptor superfamily, member 23 Neighboring gene STARR-positive B cell enhancer ABC_E10486

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A genomic reservoir for Tnfrsf genes is developmentally regulated and imprinted in the mouse. de la Casa Esperón E, et al. Epigenetics, 2012 Jun 1. PMID 22595876, Free PMC Article
  2. Identification of a new murine tumor necrosis factor receptor locus that contains two novel murine receptors for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). Schneider P, et al. J Biol Chem, 2003 Feb 14. PMID 12466268
  3. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
tumor necrosis factor receptor superfamily member 26
Names
TNF receptor homolog 3
tumor necrosis factor receptor superfamily, member 24

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175649.5 → NP_783580.1  tumor necrosis factor receptor superfamily member 26 precursor

    See identical proteins and their annotated locations for NP_783580.1

    Status: PROVISIONAL

    Source sequence(s)
    AY165628
    Consensus CDS
    CCDS40199.1
    UniProtKB/Swiss-Prot
    P83626
    UniProtKB/TrEMBL
    A7MCW7, Q3U3N2
    Related
    ENSMUSP00000054938.8, ENSMUST00000055723.9
    Conserved Domains (1) summary
    cd15837
    Location:27 → 143
    TNFRSF26; Tumor necrosis factor receptor superfamily member 26 (TNFRSF26), also known as tumor necrosis factor receptor homolog 3 (TNFRH3)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    143161422..143181690 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036153125.1 → XP_036009018.1  tumor necrosis factor receptor superfamily member 26 isoform X1

    UniProtKB/TrEMBL
    A7MCW7
    Conserved Domains (1) summary
    cd15837
    Location:27 → 143
    TNFRSF26; Tumor necrosis factor receptor superfamily member 26 (TNFRSF26), also known as tumor necrosis factor receptor homolog 3 (TNFRH3)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P83626.1 GenPept UniProtKB/Swiss-Prot:P83626

Gene LinkOut

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