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Cimap2 ciliary microtubule associated protein 2 [ Mus musculus (house mouse) ]

Gene ID: 242602, updated on 21-Apr-2024

Summary

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Official Symbol
Cimap2provided by MGI
Official Full Name
ciliary microtubule associated protein 2provided by MGI
Primary source
MGI:MGI:2681853
See related
Ensembl:ENSMUSG00000054362 AllianceGenome:MGI:2681853
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Lexm
Summary
Enables mitochondrial ribosome binding activity. Acts upstream of or within positive regulation of cell population proliferation and positive regulation of oxidative phosphorylation. Located in mitochondrion. Orthologous to human LEXM (lymphocyte expansion molecule). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 13.2) See more
Orthologs
human all
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Genomic context

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Location:
4 C7; 4 49.67 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (106448105..106474594, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (106590908..106617397, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2700068H02 gene Neighboring gene STARR-positive B cell enhancer ABC_E10243 Neighboring gene 24-dehydrocholesterol reductase Neighboring gene STARR-seq mESC enhancer starr_10995 Neighboring gene STARR-seq mESC enhancer starr_10996 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:106287642-106287893 Neighboring gene STARR-positive B cell enhancer ABC_E10244 Neighboring gene tetratricopeptide repeat domain 22 Neighboring gene STARR-positive B cell enhancer ABC_E2700 Neighboring gene prolyl-tRNA synthetase (mitochondrial)(putative)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Chemically induced (ENU) (1) 
  • Endonuclease-mediated (1) 

General gene information

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Homology

Clone Names

  • MGC58608

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables mitochondrial ribosome binding IDA
Inferred from Direct Assay
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within positive regulation of cell population proliferation IGI
Inferred from Genetic Interaction
more info
  
acts_upstream_of_or_within positive regulation of oxidative phosphorylation IGI
Inferred from Genetic Interaction
more info
  
Component Evidence Code Pubs
located_in mitochondrion IDA
Inferred from Direct Assay
more info
  

General protein information

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Preferred Names
ciliary microtubule-associated protein 2
Names
lymphocyte expansion molecule

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_183182.4 → NP_899005.2  ciliary microtubule-associated protein 2

    See identical proteins and their annotated locations for NP_899005.2

    Status: VALIDATED

    Source sequence(s)
    AL929585
    Consensus CDS
    CCDS51252.1
    UniProtKB/Swiss-Prot
    A2AVQ4, A2AVQ5, Q7TPM4
    UniProtKB/TrEMBL
    A0A0F6T326
    Related
    ENSMUSP00000102400.2, ENSMUST00000106788.2

RNA

  1. NR_149753.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL929585

  2. NR_189597.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL929585

  3. NR_189598.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL929585

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    106448105..106474594 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011240528.3 → XP_011238830.1  ciliary microtubule-associated protein 2 isoform X1

  2. XM_006503086.5 → XP_006503149.1  ciliary microtubule-associated protein 2 isoform X2

  3. XM_030253564.1 → XP_030109424.1  ciliary microtubule-associated protein 2 isoform X4

  4. XM_030253565.2 → XP_030109425.1  ciliary microtubule-associated protein 2 isoform X4

  5. XM_011240529.3 → XP_011238831.1  ciliary microtubule-associated protein 2 isoform X3

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A2AVQ5.1 GenPept UniProtKB/Swiss-Prot:A2AVQ5

Gene LinkOut

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