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Tmem245 transmembrane protein 245 [ Mus musculus (house mouse) ]

Gene ID: 242474, updated on 5-Mar-2024

Summary

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Official Symbol
Tmem245provided by MGI
Official Full Name
transmembrane protein 245provided by MGI
Primary source
MGI:MGI:2445107
See related
Ensembl:ENSMUSG00000055296 AllianceGenome:MGI:2445107
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
A630051L19Rik; D730040F13Rik
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in blood vessel; dorsal root ganglion; trigeminal ganglion; vagus ganglion; and vestibulo-cochlear ganglion. Orthologous to human TMEM245 (transmembrane protein 245). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in heart adult (RPKM 6.9), lung adult (RPKM 6.3) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
4 B3; 4 31.66 cM
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (56866923..56947456, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (56876003..56947455, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene elongator complex protein 1 Neighboring gene actin binding transcription modulator Neighboring gene catenin alpha like 1 Neighboring gene STARR-seq mESC enhancer starr_10312 Neighboring gene STARR-positive B cell enhancer ABC_E9083 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:56928950-56929103 Neighboring gene predicted gene, 25053 Neighboring gene STARR-seq mESC enhancer starr_10314 Neighboring gene microRNA 32 Neighboring gene predicted gene, 22300 Neighboring gene STARR-seq mESC enhancer starr_10316 Neighboring gene ferric-chelate reductase 1 like Neighboring gene erythrocyte membrane protein band 4.1 like 4b Neighboring gene predicted gene, 34738

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification of transcripts with enriched expression in the developing and adult pancreas. Hoffman BG, et al. Genome Biol, 2008. PMID 18554416, Free PMC Article
  2. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  3. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
  4. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transmembrane protein 245
Names
likely ortholog of H. sapiens chromosome 9 open reading frame 5 (C9orf5)
transmembrane 245

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001369260.1 → NP_001356189.1  transmembrane protein 245 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL929577, BX470220
    Consensus CDS
    CCDS89746.1
    UniProtKB/Swiss-Prot
    B1AZA5
    Related
    ENSMUSP00000067421.7, ENSMUST00000068792.13
    Conserved Domains (1) summary
    cl00465
    Location:591 → 837
    AI-2E_transport; AI-2E family transporter

  2. NM_001369261.1 → NP_001356190.1  transmembrane protein 245 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL929577, BX470220
    Conserved Domains (1) summary
    cl00465
    Location:583 → 829
    AI-2E_transport; AI-2E family transporter

  3. NM_175518.5 → NP_780727.3  transmembrane protein 245 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AI509120, AL929577, BB810057, BX470220, CF538713, CJ067096
    Consensus CDS
    CCDS38767.1
    UniProtKB/TrEMBL
    D3YWD3
    Related
    ENSMUSP00000103234.4, ENSMUST00000107609.4
    Conserved Domains (1) summary
    cl00465
    Location:651 → 841
    UPF0118; Domain of unknown function DUF20

RNA

  1. NR_161227.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL929577, BX470220

  2. NR_161228.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL929577, BX470220

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    56866923..56947456 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011250037.4 → XP_011248339.1  transmembrane protein 245 isoform X1

    Conserved Domains (1) summary
    cl00465
    Location:659 → 849
    AI-2E_transport; AI-2E family transporter

  2. XM_036164125.1 → XP_036020018.1  transmembrane protein 245 isoform X4

    UniProtKB/TrEMBL
    B1AZA8
    Related
    ENSMUSP00000117449.2, ENSMUST00000132816.8
    Conserved Domains (1) summary
    cl00465
    Location:214 → 404
    AI-2E_transport; AI-2E family transporter

  3. XM_011250038.4 → XP_011248340.1  transmembrane protein 245 isoform X2

  4. XM_011250039.4 → XP_011248341.1  transmembrane protein 245 isoform X3

RNA

  1. XR_004941894.1 RNA Sequence

  2. XR_004941893.1 RNA Sequence

  3. XR_001784143.3 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B1AZA5.1 GenPept UniProtKB/Swiss-Prot:B1AZA5

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