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Pabpc4l poly(A) binding protein, cytoplasmic 4-like [ Mus musculus (house mouse) ]

Gene ID: 241989, updated on 5-Mar-2024

Summary

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Official Symbol
Pabpc4lprovided by MGI
Official Full Name
poly(A) binding protein, cytoplasmic 4-likeprovided by MGI
Primary source
MGI:MGI:3643087
See related
Ensembl:ENSMUSG00000090919 AllianceGenome:MGI:3643087
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
EG241989; C330050A14Rik
Summary
Predicted to enable mRNA 3'-UTR binding activity; poly(A) binding activity; and poly(U) RNA binding activity. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasmic stress granule; cytosol; and nucleus. Orthologous to human PABPC4L (poly(A) binding protein cytoplasmic 4 like). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in limb E14.5 (RPKM 1.9), CNS E11.5 (RPKM 1.4) and 10 other tissues See more
Orthologs
human all
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Genomic context

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See Pabpc4l in Genome Data Viewer
Location:
3 B; 3 20.74 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (46395291..46402622, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (46440854..46447989, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 26081 Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 pseudogene Neighboring gene STARR-seq mESC enhancer starr_07550 Neighboring gene STARR-seq mESC enhancer starr_07551 Neighboring gene STARR-seq mESC enhancer starr_07553 Neighboring gene STARR-seq mESC enhancer starr_07554 Neighboring gene STARR-seq mESC enhancer starr_07555 Neighboring gene microRNA 6379 Neighboring gene STARR-seq mESC enhancer starr_07556 Neighboring gene STARR-seq mESC enhancer starr_07557 Neighboring gene zinc finger protein, subfamily 1A, 5 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. Tamplin OJ, et al. BMC Genomics, 2008 Oct 30. PMID 18973680, Free PMC Article
  2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables mRNA 3'-UTR binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables molecular_function ND
No biological Data available
more info
  
enables poly(A) binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables poly(U) RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cytoplasmic stress granule IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
polyadenylate-binding protein 4-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001101479.2 → NP_001094949.1  polyadenylate-binding protein 4-like

    See identical proteins and their annotated locations for NP_001094949.1

    Status: VALIDATED

    Source sequence(s)
    AC101968
    Consensus CDS
    CCDS50904.1
    UniProtKB/TrEMBL
    G5E8X2
    Related
    ENSMUSP00000126224.2, ENSMUST00000166505.7
    Conserved Domains (1) summary
    TIGR01628
    Location:10 → 369
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family

  2. NM_001416286.1 → NP_001403215.1  polyadenylate-binding protein 4-like

    Status: VALIDATED

    Source sequence(s)
    AC101968
    UniProtKB/TrEMBL
    G5E8X2

  3. NM_001416287.1 → NP_001403216.1  polyadenylate-binding protein 4-like

    Status: VALIDATED

    Source sequence(s)
    AC101968
    UniProtKB/TrEMBL
    G5E8X2

  4. NM_001416288.1 → NP_001403217.1  polyadenylate-binding protein 4-like

    Status: VALIDATED

    Source sequence(s)
    AC101968
    UniProtKB/TrEMBL
    G5E8X2
    Related
    ENSMUSP00000141300.2, ENSMUST00000192793.6

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    46395291..46402622 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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