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Kcnk15 potassium channel, subfamily K, member 15 [ Mus musculus (house mouse) ]

Gene ID: 241769, updated on 5-Mar-2024

Summary

Official Symbol
Kcnk15provided by MGI
Official Full Name
potassium channel, subfamily K, member 15provided by MGI
Primary source
MGI:MGI:2675209
See related
Ensembl:ENSMUSG00000035238 AllianceGenome:MGI:2675209
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
KT3.3; TASK5; KCNK11; KCNK14
Summary
Predicted to enable potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be integral component of plasma membrane. Orthologous to human KCNK15 (potassium two pore domain channel subfamily K member 15). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in frontal lobe adult (RPKM 1.9), ovary adult (RPKM 0.9) and 1 other tissue See more
Orthologs
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Genomic context

Location:
2 H3; 2 84.51 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (163695670..163700794)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (163853750..163858874)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene protein kinase inhibitor, gamma Neighboring gene adenosine deaminase intronic regulatory elements Neighboring gene adenosine deaminase upstream regulatory elements Neighboring gene adenosine deaminase Neighboring gene cellular communication network factor 5 Neighboring gene regulating synaptic membrane exocytosis 4 Neighboring gene predicted gene, 35886

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (2) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables outward rectifier potassium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
NOT enables potassium channel activity ISO
Inferred from Sequence Orthology
more info
 
enables potassium ion leak channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in potassium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in stabilization of membrane potential IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
potassium channel subfamily K member 15

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001030292.1NP_001025463.1  potassium channel subfamily K member 15

    See identical proteins and their annotated locations for NP_001025463.1

    Status: PROVISIONAL

    Source sequence(s)
    AL731698
    Consensus CDS
    CCDS17017.1
    UniProtKB/TrEMBL
    A2AHD2, B2RVL1
    Related
    ENSMUSP00000048326.4, ENSMUST00000044798.4
    Conserved Domains (1) summary
    pfam07885
    Location:96151
    Ion_trans_2; Ion channel

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    163695670..163700794
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)