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Ppp1r26 protein phosphatase 1, regulatory subunit 26 [ Mus musculus (house mouse) ]

Gene ID: 241289, updated on 5-Mar-2024

Summary

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Official Symbol
Ppp1r26provided by MGI
Official Full Name
protein phosphatase 1, regulatory subunit 26provided by MGI
Primary source
MGI:MGI:2685193
See related
Ensembl:ENSMUSG00000035829 AllianceGenome:MGI:2685193
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm347; Kiaa0649; mKIAA0649
Summary
Predicted to enable protein phosphatase inhibitor activity. Predicted to be involved in negative regulation of phosphatase activity. Predicted to be located in nucleus. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and respiratory system. Orthologous to human PPP1R26 (protein phosphatase 1 regulatory subunit 26). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E18 (RPKM 5.2), whole brain E14.5 (RPKM 4.8) and 20 other tissues See more
Orthologs
human all
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Genomic context

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Location:
2 A3; 2 19.38 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (28336613..28345520)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (28446493..28455508)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_04018 Neighboring gene olfactomedin 1 Neighboring gene predicted gene 13373 Neighboring gene STARR-seq mESC enhancer starr_04019 Neighboring gene STARR-seq mESC enhancer starr_04020 Neighboring gene piercer of microtubule wall 1 Neighboring gene ribosomal protein SA, pseudogene 9 Neighboring gene mitochondrial ribosomal protein S2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2004 Jun 30. PMID 15368895
  2. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

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Markers

Homology

Clone Names

  • MGC99945

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein phosphatase inhibitor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in negative regulation of phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein phosphatase 1 regulatory subunit 26

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005420.3 → NP_001005420.1  protein phosphatase 1 regulatory subunit 26

    See identical proteins and their annotated locations for NP_001005420.1

    Status: VALIDATED

    Source sequence(s)
    AL772249
    Consensus CDS
    CCDS15836.1
    UniProtKB/Swiss-Prot
    Q6A025, Q6NS64
    Conserved Domains (1) summary
    pfam15740
    Location:1 → 806
    PPP1R26_N; Protein phosphatase 1 regulatory subunit 26 N-terminus

  2. NM_001368159.2 → NP_001355088.1  protein phosphatase 1 regulatory subunit 26

    Status: VALIDATED

    Source sequence(s)
    AL772249
    Consensus CDS
    CCDS15836.1
    UniProtKB/Swiss-Prot
    Q6A025, Q6NS64
    Conserved Domains (1) summary
    pfam15740
    Location:1 → 806
    PPP1R26_N; Protein phosphatase 1 regulatory subunit 26 N-terminus

  3. NM_001411194.1 → NP_001398123.1  protein phosphatase 1 regulatory subunit 26

    Status: VALIDATED

    Source sequence(s)
    AL772249
    UniProtKB/Swiss-Prot
    Q6A025, Q6NS64

  4. NM_001411195.1 → NP_001398124.1  protein phosphatase 1 regulatory subunit 26

    Status: VALIDATED

    Source sequence(s)
    AL772249
    UniProtKB/Swiss-Prot
    Q6A025, Q6NS64

  5. NM_001411196.1 → NP_001398125.1  protein phosphatase 1 regulatory subunit 26

    Status: VALIDATED

    Source sequence(s)
    AL772249
    UniProtKB/Swiss-Prot
    Q6A025, Q6NS64

  6. NM_001411197.1 → NP_001398126.1  protein phosphatase 1 regulatory subunit 26

    Status: VALIDATED

    Source sequence(s)
    AL772249
    UniProtKB/Swiss-Prot
    Q6A025, Q6NS64

  7. NM_001411198.1 → NP_001398127.1  protein phosphatase 1 regulatory subunit 26

    Status: VALIDATED

    Source sequence(s)
    AL772249
    UniProtKB/Swiss-Prot
    Q6A025, Q6NS64

  8. NM_001411199.1 → NP_001398128.1  protein phosphatase 1 regulatory subunit 26

    Status: VALIDATED

    Source sequence(s)
    AL772249
    UniProtKB/Swiss-Prot
    Q6A025, Q6NS64
    Related
    ENSMUSP00000042173.8, ENSMUST00000040324.14

  9. NM_001411200.1 → NP_001398129.1  protein phosphatase 1 regulatory subunit 26

    Status: VALIDATED

    Source sequence(s)
    AL772249
    UniProtKB/Swiss-Prot
    Q6A025, Q6NS64

  10. NM_001411201.1 → NP_001398130.1  protein phosphatase 1 regulatory subunit 26

    Status: VALIDATED

    Source sequence(s)
    AL772249
    UniProtKB/Swiss-Prot
    Q6A025, Q6NS64

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    28336613..28345520
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6A025.2 GenPept UniProtKB/Swiss-Prot:Q6A025

Gene LinkOut

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