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Brd10 bromodomain containing 10 [ Mus musculus (house mouse) ]

Gene ID: 240613, updated on 5-Mar-2024

Summary

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Official Symbol
Brd10provided by MGI
Official Full Name
bromodomain containing 10provided by MGI
Primary source
MGI:MGI:2444398
See related
Ensembl:ENSMUSG00000046138 AllianceGenome:MGI:2444398
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm9832; mKIAA2026; 9930021J03Rik
Summary
Is expressed in olfactory epithelium and vomeronasal organ. Orthologous to human KIAA2026 (KIAA2026). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E18 (RPKM 5.1), whole brain E14.5 (RPKM 5.0) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
19 C1; 19 24.3 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (29691802..29784273, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (29714402..29806548, complement)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 36126 Neighboring gene STARR-seq mESC enhancer starr_45893 Neighboring gene STARR-seq mESC enhancer starr_45894 Neighboring gene melan-A Neighboring gene STARR-positive B cell enhancer ABC_E7643 Neighboring gene RAN binding protein 6 Neighboring gene STARR-seq mESC enhancer starr_45896 Neighboring gene STARR-seq mESC enhancer starr_45897 Neighboring gene predicted gene, 41832 Neighboring gene predicted gene, 36209

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
  2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  3. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  4. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • KIAA2026

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
uncharacterized protein KIAA2026 homolog
Names
bromo domain

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172836.4 → NP_766424.2  uncharacterized protein KIAA2026 homolog

    Status: VALIDATED

    Source sequence(s)
    AC120159
    UniProtKB/TrEMBL
    H3BL88
    Related
    ENSMUSP00000135696.2, ENSMUST00000175726.8
    Conserved Domains (3) summary
    cd04369
    Location:137 → 193
    Bromodomain; Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    pfam05672
    Location:253 → 292
    MAP7; MAP7 (E-MAP-115) family
    cl20817
    Location:245 → 289
    GBP_C; Guanylate-binding protein, C-terminal domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    29691802..29784273 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006527072.5 → XP_006527135.1  uncharacterized protein KIAA2026 homolog isoform X4

    UniProtKB/TrEMBL
    H3BL88
    Conserved Domains (5) summary
    cd04369
    Location:137 → 193
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    PRK03918
    Location:601 → 799
    PRK03918; DNA double-strand break repair ATPase Rad50
    TIGR03502
    Location:1251 → 1377
    lipase_Pla1_cef; extracellular lipase, Pla-1/cef family
    pfam05109
    Location:1472 → 1828
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam17061
    Location:937 → 1074
    PARM

  2. XM_017318195.3 → XP_017173684.1  uncharacterized protein KIAA2026 homolog isoform X6

    UniProtKB/TrEMBL
    H3BL88
    Conserved Domains (4) summary
    cd04369
    Location:137 → 193
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    TIGR03502
    Location:1190 → 1316
    lipase_Pla1_cef; extracellular lipase, Pla-1/cef family
    pfam05109
    Location:1411 → 1767
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam17061
    Location:876 → 1013
    PARM

  3. XM_017318193.3 → XP_017173682.1  uncharacterized protein KIAA2026 homolog isoform X2

    UniProtKB/TrEMBL
    H3BL88
    Conserved Domains (4) summary
    cd04369
    Location:137 → 193
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    TIGR03502
    Location:1323 → 1449
    lipase_Pla1_cef; extracellular lipase, Pla-1/cef family
    pfam05109
    Location:1544 → 1900
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam17061
    Location:1009 → 1146
    PARM

  4. XM_017318194.3 → XP_017173683.1  uncharacterized protein KIAA2026 homolog isoform X5

    UniProtKB/TrEMBL
    H3BL88
    Conserved Domains (3) summary
    cd04369
    Location:137 → 193
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    TIGR03502
    Location:1220 → 1346
    lipase_Pla1_cef; extracellular lipase, Pla-1/cef family
    pfam05109
    Location:1441 → 1797
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

  5. XM_006527069.5 → XP_006527132.1  uncharacterized protein KIAA2026 homolog isoform X1

    UniProtKB/TrEMBL
    H3BKP8, H3BL88
    Related
    ENSMUSP00000135473.2, ENSMUST00000177155.8
    Conserved Domains (5) summary
    cd04369
    Location:137 → 193
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    PRK03918
    Location:703 → 901
    PRK03918; DNA double-strand break repair ATPase Rad50
    TIGR03502
    Location:1353 → 1479
    lipase_Pla1_cef; extracellular lipase, Pla-1/cef family
    pfam05109
    Location:1574 → 1930
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam17061
    Location:1039 → 1176
    PARM

  6. XM_006527070.5 → XP_006527133.1  uncharacterized protein KIAA2026 homolog isoform X3

    UniProtKB/TrEMBL
    H3BL88
    Conserved Domains (5) summary
    cd04369
    Location:137 → 193
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    PRK03918
    Location:668 → 866
    PRK03918; DNA double-strand break repair ATPase Rad50
    TIGR03502
    Location:1318 → 1444
    lipase_Pla1_cef; extracellular lipase, Pla-1/cef family
    pfam05109
    Location:1539 → 1895
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam17061
    Location:1004 → 1141
    PARM

  7. XM_017318196.3 → XP_017173685.1  uncharacterized protein KIAA2026 homolog isoform X8

    UniProtKB/TrEMBL
    H3BL88
    Conserved Domains (4) summary
    PRK03918
    Location:421 → 619
    PRK03918; DNA double-strand break repair ATPase Rad50
    TIGR03502
    Location:1071 → 1197
    lipase_Pla1_cef; extracellular lipase, Pla-1/cef family
    pfam05109
    Location:1292 → 1648
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam17061
    Location:757 → 894
    PARM

  8. XM_036161593.1 → XP_036017486.1  uncharacterized protein KIAA2026 homolog isoform X7

    UniProtKB/TrEMBL
    H3BL88
    Conserved Domains (2) summary
    PRK03918
    Location:473 → 671
    PRK03918; DNA double-strand break repair ATPase Rad50
    pfam05109
    Location:1344 → 1700
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

  9. XM_030250937.2 → XP_030106797.1  uncharacterized protein KIAA2026 homolog isoform X9

    UniProtKB/TrEMBL
    H3BJL2
    Conserved Domains (1) summary
    PRK13042
    Location:876 → 981
    PRK13042; superantigen-like protein SSL4; Reviewed

  10. XM_030250938.1 → XP_030106798.1  uncharacterized protein KIAA2026 homolog isoform X10

    UniProtKB/TrEMBL
    H3BJL2
    Related
    ENSMUSP00000135031.3, ENSMUST00000175764.9
    Conserved Domains (1) summary
    PRK13042
    Location:871 → 976
    PRK13042; superantigen-like protein SSL4; Reviewed

RNA

  1. XR_003952789.2 RNA Sequence

  2. XR_001782588.3 RNA Sequence

  3. XR_003952791.2 RNA Sequence

  4. XR_004940143.1 RNA Sequence

  5. XR_001782590.3 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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