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Pcyox1l prenylcysteine oxidase 1 like [ Mus musculus (house mouse) ]

Gene ID: 240334, updated on 11-Apr-2024

Summary

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Official Symbol
Pcyox1lprovided by MGI
Official Full Name
prenylcysteine oxidase 1 likeprovided by MGI
Primary source
MGI:MGI:3606062
See related
Ensembl:ENSMUSG00000024579 AllianceGenome:MGI:3606062
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C630049M13
Summary
Predicted to enable prenylcysteine oxidase activity. Predicted to be involved in prenylated protein catabolic process. Predicted to be located in extracellular region. Orthologous to human PCYOX1L (prenylcysteine oxidase 1 like). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in whole brain E14.5 (RPKM 10.6), CNS E11.5 (RPKM 8.5) and 27 other tissues See more
Orthologs
human all
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Genomic context

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See Pcyox1l in Genome Data Viewer
Location:
18 E1; 18 34.68 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (61829907..61840712, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (61696164..61708114, complement)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene cardiac mesoderm enhancer-associated non-coding RNA Neighboring gene microRNA 143 Neighboring gene interleukin 17B Neighboring gene predicted gene, 38165 Neighboring gene STARR-positive B cell enhancer mm9_chr18:61857809-61858110 Neighboring gene STARR-seq mESC enhancer starr_44762 Neighboring gene GrpE-like 2, mitochondrial Neighboring gene predicted gene, 17883 Neighboring gene STARR-positive B cell enhancer ABC_E8720 Neighboring gene RIKEN cDNA 1500015A07 gene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Prenylcysteine oxidase 1 like protein is required for neutrophil bactericidal activities. Petenkova A, et al. Nat Commun, 2023 May 13. PMID 37179332, Free PMC Article
  2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Prenylcysteine oxidase 1 like protein is required for neutrophil bactericidal activities.
    Title: Prenylcysteine oxidase 1 like protein is required for neutrophil bactericidal activities.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor IEA
Inferred from Electronic Annotation
more info
  
enables prenylcysteine oxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in prenylated protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in prenylcysteine catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
prenylcysteine oxidase-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001418426.1 → NP_001405355.1  prenylcysteine oxidase-like isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC125157

  2. NM_001418431.1 → NP_001405360.1  prenylcysteine oxidase-like isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AC125157

  3. NM_001418432.1 → NP_001405361.1  prenylcysteine oxidase-like isoform 4 precursor

    Status: VALIDATED

    Source sequence(s)
    AC125157

  4. NM_001418435.1 → NP_001405364.1  prenylcysteine oxidase-like isoform 5 precursor

    Status: VALIDATED

    Source sequence(s)
    AC125157

  5. NM_001418439.1 → NP_001405368.1  prenylcysteine oxidase-like isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC125157

  6. NM_001418441.1 → NP_001405370.1  prenylcysteine oxidase-like isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC125157

  7. NM_001418444.1 → NP_001405373.1  prenylcysteine oxidase-like isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC125157

  8. NM_001418446.1 → NP_001405375.1  prenylcysteine oxidase-like isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC125157

  9. NM_172832.5 → NP_766420.1  prenylcysteine oxidase-like isoform 1 precursor

    See identical proteins and their annotated locations for NP_766420.1

    Status: VALIDATED

    Source sequence(s)
    AC125157
    Consensus CDS
    CCDS29287.1
    UniProtKB/Swiss-Prot
    Q8C7K6
    Related
    ENSMUSP00000025472.2, ENSMUST00000025472.7
    Conserved Domains (2) summary
    pfam07156
    Location:122 → 484
    Prenylcys_lyase; Prenylcysteine lyase
    pfam13450
    Location:31 → 96
    NAD_binding_8; NAD(P)-binding Rossmann-like domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    61829907..61840712 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8C7K6.1 GenPept UniProtKB/Swiss-Prot:Q8C7K6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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