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Zfp799 zinc finger protein 799 [ Mus musculus (house mouse) ]

Gene ID: 240064, updated on 8-Feb-2024

Summary

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Official Symbol
Zfp799provided by MGI
Official Full Name
zinc finger protein 799provided by MGI
Primary source
MGI:MGI:2443934
See related
Ensembl:ENSMUSG00000095253 AllianceGenome:MGI:2443934
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
6030490I01Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in diencephalon floor plate; early conceptus; inner cell mass; limb mesenchyme; and midbrain floor plate. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in whole brain E14.5 (RPKM 4.0), CNS E11.5 (RPKM 3.5) and 27 other tissues See more
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Genomic context

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Location:
17 B1; 17 17.98 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (33031125..33049235, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (32815449..32830261, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr17:32925111-32925412 Neighboring gene predicted gene 17115 Neighboring gene zinc finger protein 811 Neighboring gene predicted gene, 23294 Neighboring gene zinc finger protein 458 pseudogene Neighboring gene predicted gene 7059

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
  2. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
  3. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  4. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 799

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001293229.1 → NP_001280158.1  zinc finger protein 799 isoform 2

    See identical proteins and their annotated locations for NP_001280158.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate 3'-terminal exon, which extends past a splice site that is used in variant 3. The encoded isoform (2) has a shorter and distinct C-terminus.
    Source sequence(s)
    BC062813, CT485613
    Consensus CDS
    CCDS79529.1
    UniProtKB/TrEMBL
    A0A0J9YUA4, A0A0J9YUH8, Q6P5N6
    Related
    ENSMUSP00000143907.2, ENSMUST00000201499.2
    Conserved Domains (1) summary
    pfam01352
    Location:4 → 40
    KRAB; KRAB box

  2. NM_001360479.1 → NP_001347408.1  zinc finger protein 799 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) encodes the longest isoform (3).
    Source sequence(s)
    CT485613
    Conserved Domains (3) summary
    COG5048
    Location:251 → 638
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:227 → 247
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:3 → 44
    KRAB; KRAB box

  3. NM_177359.5 → NP_796333.3  zinc finger protein 799 isoform 1

    See identical proteins and their annotated locations for NP_796333.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) uses an alternate in-frame splice site in the 3' coding region, compared to variant 3. It encodes isoform 1 which is shorter, compared to isoform 3z.
    Source sequence(s)
    AK031686, BC096552, BM933667, CT485613
    Consensus CDS
    CCDS79530.1
    UniProtKB/TrEMBL
    Q8BHK4
    Related
    ENSMUSP00000144480.2, ENSMUST00000202988.4
    Conserved Domains (4) summary
    COG5048
    Location:145 → 548
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:225 → 245
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:4 → 40
    KRAB; KRAB box
    pfam13465
    Location:237 → 262
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    33031125..33049235 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011246442.4 → XP_011244744.1  zinc finger protein 799 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:248 → 635
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:224 → 244
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:3 → 44
    KRAB; KRAB box

  2. XM_011246441.4 → XP_011244743.1  zinc finger protein 799 isoform X1

    Conserved Domains (3) summary
    COG5048
    Location:250 → 637
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:226 → 246
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:3 → 44
    KRAB; KRAB box
Nucleotide Protein Strain
Heading Accession and Version

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