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Cd200r4 CD200 receptor 4 [ Mus musculus (house mouse) ]

Gene ID: 239849, updated on 21-Apr-2024

Summary

Official Symbol
Cd200r4provided by MGI
Official Full Name
CD200 receptor 4provided by MGI
Primary source
MGI:MGI:3036289
See related
Ensembl:ENSMUSG00000062082 AllianceGenome:MGI:3036289
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MCD200RLa; F630107N04Rik
Summary
Enables signaling receptor activity. Predicted to be involved in regulation of neuroinflammatory response. Located in external side of plasma membrane. Is expressed in ductus deferens; epididymis; ileum; and tongue. Orthologous to human CD200R1 (CD200 receptor 1) and CD200R1L (CD200 receptor 1 like). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

Location:
16 B4; 16 29.12 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (44632036..44659497)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (44811650..44839150)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene lactate dehydrogenase A pseudogene Neighboring gene synaptotagmin binding, cytoplasmic RNA interacting protein pseudogene Neighboring gene lactate dehydrogenase A pseudogene Neighboring gene Cd200 receptor 2 Neighboring gene predicted gene, 53957 Neighboring gene Cd200 receptor 2 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (3) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables signaling receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of neuroinflammatory response IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cell surface ISO
Inferred from Sequence Orthology
more info
 
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
cell surface glycoprotein CD200 receptor 4
Names
CD200 cell surface glycoprotein receptor
CD200 cell surface glycoprotein receptor-like 4
CD200 cell surface glycoprotein receptor-like a
CD200 receptor-like 4
CD200RLa
cell surface glycoprotein OX2 receptor 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_207244.3NP_997127.1  cell surface glycoprotein CD200 receptor 4 precursor

    See identical proteins and their annotated locations for NP_997127.1

    Status: VALIDATED

    Source sequence(s)
    AC122217
    Consensus CDS
    CCDS37346.1
    UniProtKB/Swiss-Prot
    Q6XJV4
    Related
    ENSMUSP00000135299.2, ENSMUST00000176819.8
    Conserved Domains (1) summary
    cl11960
    Location:42147
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    44632036..44659497
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011245895.4XP_011244197.1  cell surface glycoprotein CD200 receptor 4 isoform X2

    See identical proteins and their annotated locations for XP_011244197.1

    UniProtKB/TrEMBL
    H3BJX3
    Related
    ENSMUSP00000135162.3, ENSMUST00000176321.8
    Conserved Domains (1) summary
    cl11960
    Location:116184
    Ig; Immunoglobulin domain