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Ccdc14 coiled-coil domain containing 14 [ Mus musculus (house mouse) ]

Gene ID: 239839, updated on 3-Apr-2024

Summary

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Official Symbol
Ccdc14provided by MGI
Official Full Name
coiled-coil domain containing 14provided by MGI
Primary source
MGI:MGI:2443448
See related
Ensembl:ENSMUSG00000022833 AllianceGenome:MGI:2443448
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
G630039H03Rik
Summary
Predicted to be involved in protein localization to centrosome. Predicted to be located in centrosome. Predicted to be active in centriolar satellite. Orthologous to human CCDC14 (coiled-coil domain containing 14). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E11.5 (RPKM 3.3), testis adult (RPKM 2.7) and 26 other tissues See more
Orthologs
human all
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Genomic context

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Location:
16 B3; 16 24.46 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (34510940..34545574)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (34690557..34725204)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene kalirin, RhoGEF kinase Neighboring gene STARR-seq mESC enhancer starr_40723 Neighboring gene STARR-seq mESC enhancer starr_40724 Neighboring gene predicted gene, 41448 Neighboring gene STARR-seq mESC enhancer starr_40725 Neighboring gene STARR-positive B cell enhancer ABC_E5539 Neighboring gene ropporin, rhophilin associated protein 1 Neighboring gene predicted gene, 35150 Neighboring gene STARR-seq mESC enhancer starr_40726 Neighboring gene myosin, light polypeptide kinase Neighboring gene RIKEN cDNA 1700119H24 gene Neighboring gene STARR-seq mESC enhancer starr_40727 Neighboring gene predicted gene, 53951

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo. Evsikov AV, et al. Genes Dev, 2006 Oct 1. PMID 17015433, Free PMC Article
  2. An Interaction Landscape of Ubiquitin Signaling. Zhang X, et al. Mol Cell, 2017 Mar 2. PMID 28190767
  3. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  4. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in protein localization to centrosome IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein localization to centrosome ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in centriolar satellite IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in centriolar satellite ISO
Inferred from Sequence Orthology
more info
  
located_in centrosome ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
coiled-coil domain-containing protein 14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172824.4 → NP_766412.3  coiled-coil domain-containing protein 14

    Status: VALIDATED

    Source sequence(s)
    AC154456
    Consensus CDS
    CCDS49837.1
    UniProtKB/TrEMBL
    A0A338P6V9
    Related
    ENSMUSP00000156124.2, ENSMUST00000231609.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    34510940..34545574
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036159922.1 → XP_036015815.1  coiled-coil domain-containing protein 14 isoform X1

    Conserved Domains (1) summary
    pfam15254
    Location:96 → 627
    CCDC14; Coiled-coil domain-containing protein 14

  2. XM_011245891.4 → XP_011244193.1  coiled-coil domain-containing protein 14 isoform X2

    See identical proteins and their annotated locations for XP_011244193.1

    Conserved Domains (1) summary
    pfam15254
    Location:96 → 510
    CCDC14; Coiled-coil domain-containing protein 14

  3. XM_030249111.1 → XP_030104971.1  coiled-coil domain-containing protein 14 isoform X3

    Conserved Domains (1) summary
    pfam15254
    Location:2 → 498
    CCDC14; Coiled-coil domain-containing protein 14

RNA

  1. XR_384564.4 RNA Sequence

  2. XR_003951790.2 RNA Sequence

  3. XR_004939191.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8K2J4.3 GenPept UniProtKB/Swiss-Prot:Q8K2J4

Gene LinkOut

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