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AU021092 expressed sequence AU021092 [ Mus musculus (house mouse) ]

Gene ID: 239691, updated on 5-Mar-2024

Summary

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Official Symbol
AU021092provided by MGI
Official Full Name
expressed sequence AU021092provided by MGI
Primary source
MGI:MGI:2146559
See related
Ensembl:ENSMUSG00000051669 AllianceGenome:MGI:2146559
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable protein homodimerization activity. Predicted to be located in extracellular region. Predicted to be active in cytosol and membrane. Is expressed in foregut; male reproductive gland or organ; metanephros; and respiratory system. Orthologous to human C16orf89 (chromosome 16 open reading frame 89). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in lung adult (RPKM 52.8), ovary adult (RPKM 31.7) and 12 other tissues See more
Orthologs
human all
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Genomic context

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Location:
16 A1; 16 2.51 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (5029677..5040170, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (5211814..5222308, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene SEC14-like lipid binding 5 Neighboring gene N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Neighboring gene microRNA 6364 Neighboring gene STARR-positive B cell enhancer mm9_chr16:5233472-5233773 Neighboring gene ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase Neighboring gene eukaryotic elongation factor 2 lysine methyltransferase Neighboring gene predicted gene 15983 Neighboring gene predicted gene, 57635

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Initial characterization of C16orf89, a novel thyroid-specific gene. Afink GB, et al. Thyroid, 2010 Jul. PMID 20578903
  2. A mouse knockout library for secreted and transmembrane proteins. Tang T, et al. Nat Biotechnol, 2010 Jul. PMID 20562862
  3. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
  4. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
  5. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (4)  1 citation
  • Endonuclease-mediated (2) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
UPF0764 protein C16orf89 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033220.4 → NP_001028392.2  UPF0764 protein C16orf89 homolog isoform 1 precursor

    See identical proteins and their annotated locations for NP_001028392.2

    Status: VALIDATED

    Source sequence(s)
    AC124576
    Consensus CDS
    CCDS27934.1
    UniProtKB/Swiss-Prot
    B7ZWC6, Q3UST5
    Related
    ENSMUSP00000058860.5, ENSMUST00000050160.6
    Conserved Domains (1) summary
    pfam15882
    Location:56 → 334
    DUF4735; Domain of unknown function (DUF4735)

  2. NM_001417142.1 → NP_001404071.1  UPF0764 protein C16orf89 homolog isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC124576

  3. NM_001417143.1 → NP_001404072.1  UPF0764 protein C16orf89 homolog isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AC124576

  4. NM_001417144.1 → NP_001404073.1  UPF0764 protein C16orf89 homolog isoform 4 precursor

    Status: VALIDATED

    Source sequence(s)
    AC124576

  5. NM_001417145.1 → NP_001404074.1  UPF0764 protein C16orf89 homolog isoform 5 precursor

    Status: VALIDATED

    Source sequence(s)
    AC124576

  6. NM_001417146.1 → NP_001404075.1  UPF0764 protein C16orf89 homolog isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC124576

RNA

  1. NR_184425.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC124576

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    5029677..5040170 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036159915.1 → XP_036015808.1  UPF0764 protein C16orf89 homolog isoform X3

    Conserved Domains (1) summary
    pfam15882
    Location:56 → 116
    DUF4735; Domain of unknown function (DUF4735)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3UST5.2 GenPept UniProtKB/Swiss-Prot:Q3UST5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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